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Projects



Photo: Henseler, Copyright: BMBF

  • Identification and validation of molecular target for pharmacological treatment of alcohol dependence. In collaboration with Markus Heilig (Karolinska Institut, Stockholm), Petri Hyytiä (National Public Health Institute, Helsinki), Roberto Ciccocioppo (University of Camerino, Italien), Fernando Rodriguez de Fonseca (Hospital Carlos Haya de Malaga). Supported by the 5. EU Rahmenprogramm
  • Individual adapted pharmacotherapy. In collaboration with Werner Schmidt (University Tübingen), Andreas Heinz (Charité Berlin) and Karl Mann (ZI, Mannheim). Supported by the BMBF Suchtforschungsverbund Baden-Württemberg, LIPHA (Lyon), Abbott (Ludwigshafen), Merz GmbH (Frankfurt)
  • Identification and functional analysis of candidate genes in alcohol addiction. In collaboration with Dusan Bartsch and Gunter Schumann (ZI, Mannheim). Supported by the BMBF NGFN
  • Development of addictive behavior and alcohol derived organic diseases in rats. In collaboration with Manfred Singer (University Clinic of Mannheim), T.-K. Li (Indiana University, Indianapolis) and David Sinclair (KTL, Helsiniki). Supported by the Landesforschungsschwerpunkt Alkoholfolgekrankheiten
  • The influence of circadian rhythm and per genes on the effect of drugs of abuse. In collaboration with Urs Albrecht (University Fribourg, Schweiz). Supported by internal funds
  • Chemocine-modified transcriptomanalysis in microglia. Supported by the DFG
  • Neurochemical and molecular changes during chronic drug exposure and chronic pain. In collaboration with Jacqueline Sepulveda (University Concepcion, Chile). Supported by the DAAD, Alechile
  • The role of glucocorticoid receptors in acute and chronic effects of alcohol and cocaine. In collaboration with Francois Tronche (CNRS, Paris), Pierre Piazza (INSERM, Bordeaux), Günter Schütz (DKFZ, Heidelberg) and Inge Sillaber (Max Planck Institute of Psychiatry, Munich). Supported by the DAAD, PROCOPE
  • Identification of depression and stress relevant gene transcripts the blood of marathon runners. In collaboration with H. Northoff (Univerity Tübingen). Supported by the Blood bank Tübingen
  • Identification of depression relevant gene transcripts in a rat model of learned helplessness. In collaboration with Marcella Rietschel and Fritz A. Henn (ZI, Mannheim). Supported by the Graduiertenkolleg Heidelberg
  • ENU mutagenesis alcohol programme. In collaboration with Hrabé de Angelis (GSF, München) and Mark Latrop (Centre National de Genotypage, Paris). Supported by: French administration for research.
  • Molecular basis of conditioned drug withdrawal. Supported by the DFG/SFB
  • Molecular mechanisms of neural and synaptic plasticity in models of depression. Supported by the DFG/SFB

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