Research Papers
Meyer-Lindenberg A., M.L. Rao: Interrelationship between blood serotonin levels and affinity of platelet imipramine binding sites in healthy subjects. Pharmacopsychiatry 26(1993), 15-19.
Meyer-Lindenberg A., E. Schindler, R. Heitmann: Apurulente Streptokokkenmeningitis bei bakterieller Endokarditis. Aktuelle Neurologie 21(1994), 28-31
Meyer-Lindenberg A.: The evolution of complexity in human brain development: an EEG study. Electroencephalography Clinical Neurophysiology 99(1996), 405-411.
Meyer-Lindenberg A., B. Krausnick: Tardive Dyskinesia in a neuroleptic-free patient with bipolar I disorder: permanent exacerbation after lithium intoxication. Movement Dis 12(1997), 1108-1109.
Meyer-Lindenberg A., H. Gruppe, U. Bauer, S. Lis, S. Krieger, B. Gallhofer: Improvement of cognitive function in schizophrenic patients receiving clozapine or zotepine: results from a double-blind study. Pharmacopsychiatry 30(1997), 35-42.
Meyer-Lindenberg A., M. Hotz: Ferréol Besnier disesase with associated recurrent meningitis. J Neurology Neurosurgery Psychiatry 62(1997): 297.
Meyer-Lindenberg A, Mewes J, Biniek R: Megadolicho basilar artery as indication of intensive care relevant vertebrobasilar ischemia. Nervenarzt 1997, 68:674-7.
Meyer-Lindenberg A., T. Rammsayer, J. Ulferts, B. Gallhofer: Sulpiride versus placebo in healthy volunteers: a double-blind study of psychometric performance and subjective tolerance profiles. European Neuropsychopharmacology 7(1997), 219-223.
Gallhofer, B., S. Krieger, S. Lis, L. Hargarter, C. Roeder, C. Lammers, A. Meyer-Lindenberg: Cognitive dysfunction in schizophrenia: Maze solving behaviour in treated and untreated patients. CNS Spectrums 2(1997), 26-40.
Meyer-Lindenberg A., K. Fehmeyer, G. Schüler, S. Lis, S. Krieger, U. Bauer, B. Gallhofer: The topography of non-linear cortical dynamics at rest, in mental calculation and moving shape perception. Brain Topography 10(1998), 291-299.
Meyer-Lindenberg A, Gallhofer B: Somatized depression as a subgroup of fibromyalgia syndrome. Z Rheumatol 1998,57:92-3
Urbach H, Meyer-Lindenberg A, Bendszus M, Roggendorf W, Solymosi L: Dissections of the basilar artery. Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr 1998:170-4.
Gallhofer, B., S. Lis, A. Meyer-Lindenberg, S. Krieger: Cognitive dysfunction in schizophrenia: A new set of tools for the assessment of cognition and drug effects. Acta Psychiatrica Scand 395(1999): 118-28
Ulferts J, Meyer-Lindenberg A, Gallhofer B. Zeitdiskrimination: Ein Vergleich zwischen Gesunden, unmedizierten, mit Zotepin sowie konventionellen Neuroleptika behandelten schizophrenen Patienten. Neuropsychiatrie (1999) 13: 133-138
Heun, R, Meyer-Lindenberg A: Methodische und statistische Aspekte der funktionellen Kernspintomographie. Klin Neuroradiologie 2001, 11: 67-82.
Meyer-Lindenberg A, J.B. Poline, P. Kohn, J. Holt, M. Egan, D.R. Weinberger, K.F. Berman: Evidence for abnormal cortical functional connectivity during working memory in schizophrenia. American J Psychiatry, 158(2001), 1809-17.
Meyer-Lindenberg A, Miletich R, Kohn P, Esposito G, Carson R, Quarantelli M, Weinberger DR and Berman KF: Reduced prefrontal Cortex Activity Predicts Exaggerated Striatal Dopaminergic Function in Schizophrenia. Nature Neuroscience (2002) 5:267-271
Meyer-Lindenberg A, Ziemann U, Hajak G, Cohen L, Berman KF: Transitions between dynamical states of differing stability in the human brain. Proc Natl Acad Sci U S A 2002 99(17):10948-53
Glabus MF, Horwitz B, Holt JL, Kohn PD, Gerton BK, Callicott JH, Meyer-Lindenberg A, Berman KF: Interindividual differences in functional interactions among prefrontal, parietal and parahippocampal regions during working memory. Cereb Cortex 2003 Dec,13(12):1352-61.
Gerton BK, Brown TT, Meyer-Lindenberg A, Kohn P, Holt JL, Olsen RK, Berman KF: Shared and Distinct Neurophysiological Components of the Digits Forward and Backward Tasks as Revealed by Functional Neuroimaging. Neuropsychologia, 2004,42(13):1781-7.
Meyer-Lindenberg A, Kohn P, Mervis CB, Olsen R, Kippenhan S, Morris CA, Berman KF: Neural basis of genetically determined visuospatial construction deficit in Williams syndrome. Neuron, 2004 43(5):623-31.
Pezawas L, Verchinski B, Mattay V, Callicott J, Kolachana B, Straub R, Egan M, Meyer-Lindenberg A, Weinberger DR: The BDNF val66met polymorphism and variation in human cortical morphology. J Neurosci 2004 24(45): 10099-10102.
Hernandez DG, Paisan-Ruiz C, McInerney-Leo A, Jain S, Meyer-Lindenberg A, Evans EW, Berman KF, Johnson J, Auburger G, Schaffer AA, Lopez GJ, Nussbaum RL, Singleton AB.: Clinical and positron emission tomography of Parkinson's disease caused by LRRK2. Ann Neurol. 2005 Feb 24;57(3):453-456
Meyer-Lindenberg A, Olsen RK, Kohn PD, Holt JL, Egan MF, Weinberger DR, Berman KF: Regionally specific disturbance of dorsolateral prefrontal - hippocampal functional connectivity in schizophrenia. Arch Gen Psychiat, 2005 Apr;62(4):379-86.
Meyer-Lindenberg A, Kohn PD, Kolachana B, Kippenhan S, Mcinery-Leo A, Nussbaum RL, Weinberger DR, Berman KF: Midbrain dopamine and prefrontal function in humans: interaction and modulation by COMT genotype. Nature Neuroscience, 2005 May;8(5):594-596.
Krieger S, Lis S, Cetin T, Gallhofer B, Meyer-Lindenberg A: Executive Function and cognitive sub-processes in first-episode, drug-naïve schizophrenia: an analysis of n-back performance. American J Psychiatry, 2005 Jun;162(6):1206-8.
Pezawas L*, Meyer-Lindenberg A*, Drabant EM, Verchinski B, Mattay VS, Hariri AR, Kolachana B, Egan MF, Weinberger DR: 5-HTTLPR polymorphism impacts human cingulate-amygdala interactions: a genetic susceptibility mechanism for depression. Nature Neuroscience, 2005 Jun;8(6):828-34. (*shared first authorship)
Callicott J, Straub RE, Pezawas L, Egan MF, Mattay VS, Hariri AR, Verchinski BA, Meyer-Lindenberg A, Weinberger DR: Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia. Proc Natl Acad Sci U S A 2005 102:8627-8632
Meyer-Lindenberg A, Mervis CB, Sarpal D, Koch P, Steele S, Kohn P, Marenco S, Morris CA, Das S, Kippenhan S, Mattay VS, Weinberger DR, Berman KF: Functional, structural and metabolic abnormalities of the hippocampal formation in Williams syndrome. J Clin Investigation, 2005 115: 1888-1895.
Kippenhan S, , Olsen R, Kohn PD, Mervis CB, Morris CA, Kohn PD, Meyer-Lindenberg A*, Berman KF*: Genetic Contributions to Human Gyrification: Sulcal Morphometry in Williams Syndrome. (*shared senior authorship) J Neurosci, 2005 25: 7840-7846.
Meyer-Lindenberg A, Hariri AR, Munoz KE, Morris CA, Mervis C, Mattay VS, Berman KF: Neural correlates of genetically abnormal social cognition in Williams syndrome. Nature Neuroscience, 2005 Aug;8(8):991-993.
Kirsch P, Esslinger C, Chen Q, Mier D, Lis S, Siddhanti S, Gruppe H, Mattay VS, Gallhofer B, Meyer-Lindenberg A: Oxytocin modulates neural circuitry for social cognition and fear in humans. J Neurosci, 2005 25: 11489-11493.
Mattay VS, Fera F, Tessitore A, Hariri AR, Berman KF, Das S, Meyer-Lindenberg A, Goldberg TE, Callicott JH, Weinberger DR: Neurophysiological correlates of age-related changes in working memory capacity. Neuroscience Letters, 2006 Jan 9;392(1-2):32-7.
Meyer-Lindenberg A, Buckholtz J, Kolachana BS, Pezawas L, Blasi G, Wabnitz A, Hariri AR, Verchinski B, Callicott J, Egan MF, Mattay VS, Weinberger DR: Neural mechanisms for genetic risk for violence and impulsivity in humans. Proc Natl Acad Sci U S A, 2006 103(16): 6269-74.
Meyer-Lindenberg A, Weinberger DR: Impact of complex genetic variation in COMT on human brain function. Mol Psychiatry, 2006, 11(9): 867-877.
Meyer-Lindenberg A, Weinberger DR: COMT haplotype variation affects human prefrontal function. Mol Psychiatry 2006 11(9): 797.
Tost H, Meyer-Lindenberg A, Klein S, Schmitt A, Höhn F, Tenckhoff A, Ruf M, Ende G, Rietschel M, Henn FA, Braus DF: D2 antidopaminergic modulation of frontal lobe function in healthy human subjects. Biol Psychiatry 2006 Dec 1;60(11):1196-205.
Bertolino A, Rubino V, Sambataro F, Blasi G, Latorre V, Fazio L, Caforio G, Petruzzella V, Kolachana B, Hariri AR, Meyer-Lindenberg A, Nardini M, Weinberger DR, Scarabino T: Prefrontal-hippocampal coupling during declarative memory is associated with COMT Val158Met genotype. Biol Psychiatry 2006 Dec 1;60(11):1250-8.
Tan HY, Sust S, Buckholtz J, Mattay VS, Meyer-Lindenberg A, Weinberger DR, Callicott JH: Dysfunctional prefrontal regional specialization and its compensation in patients with schizophrenia. Am J Psychiatry, 2006; 163:1969–1977.
Drabant EM,Hariri AR, Meyer-Lindenberg A, Munoz KE, Mattay VS, Kolachana BS, Egan MF, Weinberger DR: Catechol-O-methyltransferase Val158Met genotype and neural mechanisms of emotional arousal and regulation. Arch Gen Psychiat, 2006 Dec;63(12):1396-406.
Bassett DS, Meyer-Lindenberg A, Achard S, Duke T, Bullmore E: Adaptive reconfiguration of fractal small-world human brain functional networks. Proc Natl Acad Sci U S A, 2006 103(51): 19518-23.
Meyer-Lindenberg A, Straub RE, Lipska B, Verchinski BA,Callicott J, Goldberg TE, Egan MF, Huffaker S, Mattay VS, Hariri AR, Pezawas L, Kolachana BS, Kleinman JE, Weinberger DR: Genetic evidence implicating DARPP-32 in human fronto-striatal structure, function and cognition. J Clin Investigation, 2007 Mar 1;117(3):672-682.
Buckholtz JW, Meyer-Lindenberg A, Honea R, Straub RE, Pezawas L, Egan MF, Vakkalanka R, Kolachana B, Verchinski BA, Sust S, Mattay VS, Weinberger DR, Callicott JH: Allelic Variation in RGS4 Impacts Functional and Structural Connectivity in the Human Brain. J Neurosci, 2007 Feb 14;27(7):1584-93.
Weinberger DR, Zink CF, Mattay VS, Meyer-Lindenberg A: A validated network of effective amygdala connectivity. Neuroimage, 2007 Jul 1;36(3):736-45
Buckholtz J, Callicott J, Kolachana BS, Hariri AR, Goldberg T, Genderson M, Egan MF, Mattay VS, Weinberger DR, Meyer-Lindenberg A: Genetic variation in MAOA modulates ventromedial prefrontal circuitry mediating individual differences in human personality. Mol Psychiatry, 2008 Mar;13(3):736-45. Epub 2007 May 22.
Tan HY, Chen Q, Sust S, Buckholtz JW, Kolachana BS, Straub R, Mattay VS, Meyer-Lindenberg A, Weinberger DR, Callicott JH: Epistasis between catechol-O-methyltransferase and type II metabotropic glutamate receptor 3 genes on working memory brain function. Proc Natl Acad Sci U S A, 2007 Jul 24;104(30):12536-41
Buckholtz JW, Sust S, Tan HY, Mattay VS, Straub RE, Meyer-Lindenberg A, Weinberger DR, Callicott JH: fMRI evidence for functional epistasis between COMT and RGS4. Mol Psychiatry, 2007 Oct;12(10):893-895
Buckholtz JW, Prust M, Sust S, Tan HY, Mattay VS, Straub RE, Meyer-Lindenberg A, Weinberger DR, Callicott JH: Imaging epistasis in vivo: COMT and RGS4. Mol Psychiatry, 2007 Oct;12(10):885
Goldman AL, Pezawas L, Mattay VS, Fischl B, Verchinski BA, Zoltick B, Weinberger DR, Meyer-Lindenberg A: Heritability of Brain Morphology Related to Schizophrenia: A Large-Scale Automated Magnetic Resonance Imaging Segmentation Study. Biol Psychiatry, 2008 Mar 1;63(5):465-74. Epub 2007 Aug 8.
Honea R, Meyer-Lindenberg A, Weinberger DR, Callicott JH: Is Gray Matter Volume an Intermediate Phenotype for Schizophrenia? A VBM Study of Patients with Schizophrenia and Their Healthy Siblings. Biol Psychiatry, 2007 Aug 7; (Epub ahead of print)
Marenco S, Siuta M, Kippenhan S, Grodowsky S, Chang W, Kohn PD, Mervis CB, Morris CA, Weinberger DR, Meyer-Lindenberg A, Pierpaoli C, Berman KF: Genetic contributions to white matter architecture revealed by diffusion tensor imaging in Williams Syndrome. Proc Natl Acad Sci U S A, 2007, Sep 18;104(38):15117-15122.
Tan HY, Chen Q, Kolachana BS, Goldberg T, Meyer-Lindenberg A, Weinberger D, Callicott JH: COMT Val158Met modulation of prefrontal-parietal-striatal brain systems during arithmetic and temporal transformations in working memory. J Neuroscience, 2007 Dec 5;27(49):13393-401.
Meyer-Lindenberg A, Nicodemus KK, Callicott J, Mattay VS, Weinberger DR: False positives in imaging genetics. Neuroimage, 2008 Apr 1;40(2):655-661.
Sarpal D, Buchsbaum BR, Kohn PD, Kippenhan JS, Mervis CB, Morris CA, Meyer-Lindenberg A*, Berman KF*: A Genetic Model for Understanding Higher Order Visual Processing: Functional Interactions of the Ventral Visual Stream in Williams Syndrome. (*shared senior authorship) Cerebral Cortex, 2008 Feb 27; (Epub ahead of print)
Buckholtz JW, Meyer-Lindenberg A: MAOA and the neurogenetic architecture of human aggression. Trends Neurosci. 2008 Mar;31(3):120-9. Epub 2008 Feb 6.
Dreßing H, Meyer-Lindenberg A: Simulation bei posttraumatischer Belastungsstörung. [Malingering of post-traumatic stress disorder] Versicherungsmedizin 2008; 60 (1): 8-13
Achard S, Bassett DS, Meyer-Lindenberg A, Bullmore E: Fractal connectivity of long-memory networks. Physical Review E Stat Nonlin Soft Matter Phys 2008 Mar;77(3 Pt 2):036104.
Pezawas L*, Meyer-Lindenberg A*, Goldman A, Verchinski B, Mattay VS, Hariri AR, Kolachana B, Egan MF, Weinberger DR: Evidence of biologic epistasis between BDNF and SLC6A4 and implications for depression. Mol Psychiatry, 2008 Jul;13(7):654, 709-16. (*shared first authorship)
Pezawas L*, Meyer-Lindenberg A*, Goldman A, Verchinski B, Mattay VS, Hariri AR, Kolachana B, Egan MF, Weinberger DR: MET BDNF protects against morphological S allele effects of 5-HTTLPR. Mol Psychiatry. 2008 Jul;13(7):654. (*shared first authorship)
Matsumoto M, Straub RE, Marenco S, Nicodemus KK, Matsumoto S, Fujikawa A, Miyoshi S, Shoubo M, Takahashi S, Yarimizu J, Yuri M, Hiramoto M, Morita S, Yokota H, Sasayama T, Terai K, Yoshino M, Miyake A, Callicott JH, Egan MF, Meyer-Lindenberg A, Kempf L, Honea R, Takasaki J, Kamohara M, Soga T, Hiyama H, Ishii H, Matsuo A, Nishimura S, Matsuoka N, Kobori M, Matsushime H, Katoh M, Furuichi K, and Weinberger DR: The evolutionarily conserved G-protein coupled receptor SREB2 (GPR85) influences brain size, behavior and vulnerability to schizophrenia. Proc Natl Acad Sci U S A, 2008 Apr 14;
Zink CF, Tong Y, Chen Q, Bassett DS, Stein JL. Meyer-Lindenberg A: Know Your Place: Neural Processing of Stable and Unstable Social Hierarchy in Humans. Neuron, 2008 Apr 24;58(2):273-83.
Sartorius A, Ruf M, Kief C, Demirakca T, Bailer J, Ende G, Henn FA, Meyer-Lindenberg A, Dressing H: Abnormal amygdala activation profile in pedophilia. Eur Arch Psychiatry, 2008 May 26. [Epub ahead of print]
Meyer-Lindenberg A, Weinberger DR: Genetic variation in AVPR1A linked to autism predicts amygdala activation and personality traits in healthy humans. Mol Psychiatry, 2008 May 20. [Epub ahead of print]
Tan HY, Nicodemus KK, Chen Q, Brooke JK, Honea R, Kolachana BS, Straub RE, Meyer-Lindenberg A, Weinberger DR: Converging genetic evidence that AKT1 affects dopamine associated prefrontal cortical function and structure in humans. J Clin Investigation, 2008 Jun;118(6):2200-8.
Klauschen F, Goldman A, Barra V, Meyer-Lindenberg A, Lundervold A: Evaluation of automated brain MR image segmentation and volumetry methods. Human Brain Mapping, 2008 Jun 6. [Epub ahead of print]
Falkai P, Maier W, Nöthen M, McGuire P, Owen M, Schürhoff F, Maron E, Myin-Germeys I, Meyer-Lindenberg A, Zink M, van Haren N, Lawrie S, Stefanis N, Wölwer W, Vaudano E, Shifman S, Bilkei-Gorzo A, Harrison P, de Hert M, Bitter I, Dierks T, Kasper S, Vita A, Crespo-Facorro B, di Giorgio A, Ruhrmann S, Gjedde A, Frangou S: A Roadmap to disentangle the Molecular Etiology of Schizophrenia. European Psychiatry, 2008 Jun 24. [Epub ahead of print]
Hyde TM, Deep-Soboslay A, Iglesias B, Callicott JH, Gold JM, Meyer-Lindenberg A, Honea RA, Bigelow LB, Egan MF, Emsellem EM, Weinberger DR: Enuresis as a Premorbid Developmental Marker of Schizophrenia. Brain, 2008 Jul 3. Epub ahead of print.
Dreher JC, Meyer-Lindenberg A, Kohn PD, Berman KF: Age-related changes in midbrain dopaminergic regulation of the human reward system. Proc Natl Acad Sci U S A, accepted for publication
Murty V, Sambataro F, Das S, Tan H-Y, Callicott JH, Goldberg TE, Meyer-Lindenberg A, Weinberger DR, Mattay VS: Age-related alterations in simple declarative memory and the effect of stimulus valence. J Cog Neurosci, accepted for publication
Bassett DS, Bullmore EB, Verchinski BA, Mattay VS, Weinberger DR, Meyer-Lindenberg A: Hierarchical organization of human cortical networks in health and schizophrenia. J Neuroscience, accepted for publication
Rasetti R, Mattay VS, Wiedholz LM, Kolachana BS, Hariri AR, Callicott JH, Meyer-Lindenberg A, Weinberger DR: Altered amygdala-cingulate functional coupling in schizophrenia is related to clinical state and not genetic risk. Am J Psychiatry, revision under review
Tost H, Ruf M, Schmäl C, Schulze TG, Knorr C, Vollmert C, Bößhenz K, Ende G, Meyer-Lindenberg A, Henn FA, Rietschel M: Prefrontal-temporal gray matter deficits in bipolar disorder patients with persecutory delusions. Bipolar Disorders, under review |