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2010

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Umhau JC, Momenan R, Schwandt ML, Singley E, Lifshitz M, Doty L, Adams LJ, Vengeliene V, Spanagel R, Zhang Y, Shen J, George DT, Hommer D, Heilig M (2010) Effect of acamprosate on magnetic resonance spectroscopy measures of central glutamate in detoxified alcohol-dependent individuals: a randomized controlled experimental medicine study. Arch Gen Psychiatry 67:1069-77, als PDF-file hier!  


Sommer JU, Schmitt A, Heck M, Schaeffer EL, Fendt M, Zink M, Nieselt K, Symons S, Petroianu G, Lex A, Herrera-Marschitz M, Spanagel R, Falkai P, Gebicke-Haerter PJ (2010) Differential expression of presynaptic genes in a rat model of postnatal hypoxia: relevance to schizophrenia. Eur Arch Psychiatry Clin Neurosci 260 Suppl 2:S81-9. Epub 2010 Oct 14, als PDF-file hier!  


Spanagel R, Bartsch D, Brors B, Dahmen N, Deussing J, Eils R, Ende G, Gallinat J, Gebicke-Haerter P, Heinz A, Kiefer F, Jäger W, Mann K, Matthäus F, Nöthen M, Rietschel M, Sartorius A, Schütz G, Sommer WH, Sprengel R, Walter H, Wichmann E, Wienker T, Wurst W, Zimmer (2010) An integrated genome research network for studying the genetics of alcohol addiction. Addict Biol 15:369-79, als PDF-file hier!  

Friemel CM, Spanagel R, Schneider M (2010) Reward sensitivity for a palatable food reward peaks during pubertal developmental in rats. Front Behav Neurosci 4. pii: 39, als PDF-file hier!  


Perreau-Lenz S, Sanchis-Segura C, Leonardi-Essmann F, Schneider M, Spanagel R (2010) Development of morphine-induced tolerance and withdrawal: involvement of the clock gene mPer2. Eur Neuropsychopharmacol 20, 509-517, als PDF-file hier! 

Schneider M, Heise V, Spanagel R (2010) Differential involvement of the opioid receptor antagonist naloxone in motivational and hedonic aspects of reward. Behav Brain Res, 466-472, als PDF-file hier! 

Novak M, Halbout B, O'Connor EC, Rodriguez Parkitna J, Su T, Chai M, Crombag HS, Bilbao A, Spanagel R, Stephens DN, Schütz G, Engblom D (2010) Incentive learning underlying cocaine-seeking requires mGluR5 receptors located on dopamine D1 receptor-expressing neurons. J Neurosci 30, 11973-11982, als PDF-file hier! 

Vengeliene V, Leonardi-Essmann F, Sommer WH, Marston H, Spanagel R (2010) Glycine Transporter-1 Blockade Leads to Persistently Reduced Relapse-like Alcohol Drinking in Rats. Biol Psychiatry 68, 704-711, als PDF-file hier! 
 
Brunk I, Sanchis-Segura C, Blex C, Perreau-Lenz S, Bilbao A, Spanagel R,
Ahnert-Hilger G (2010) Amphetamine regulates NR2B expression in Go2α knockout mice and thereby sustains behavioral sensitization. J Neurochem 115: 234-246, als PDF-file hier! 

Zieker D, Jenne I, Koenigsrainer I, Zdichavsky M, Niselt K, Buch K, Zieker J, Beckert S, Glatzle J, Spanagel R, Koenigsrainer A, Northoff H, Loeffler M (2010) Circadian expression of clock- and tumor suppressor genes in human oral mucosa. Cell Physiol Biochem 26:155-66, als PDF-file hier! 

Kiefer F, Witt SH, Frank J, Richter A, Treutlein J, Lemenager T, Nöthen MM, Cichon S, Batra A, Berner M, Wodarz N, Zimmermann US, Spanagel R, Wiedemann K, Smolka MN, Heinz A, Rietschel M, Mann K (2010) Involvement of the atrial natriuretic peptide transcription factor GATA4 in alcohol dependence, relapse risk and treatment response to acamprosate. Pharmacogenomics J, in press, als PDF-file hier! 

Spanagel R (2010) A call for systems approaches in addiction research. Addiction 105:791-792; discussion 795-796, als PDF-file hier! 


Spanagel R (2010) Are metabotropic glutamate receptors promising targets for the treatment of alcoholism? Biol Psychiatry 67:798-799, als PDF-file hier!

Mutschler J, Bilbao A, von der Goltz C, Demiralay C, Jahn H, Wiedemann K, Spanagel R, Kiefer F (2010) Augmented stress-induced alcohol drinking and withdrawal in mice lacking functional natriuretic peptide A receptors. Alcohol Alcoholism 45:13-6, als PDF-file hier! 

Rodriguez Parkitna JR, Bilbao A, Rieker C, Engblom D, Piechota M, Nordheim A, Spanagel R, Schütz G. Loss of the serum response factor in the dopamine system leads to hyperactivity. FASEB J 24:2427-2435, als PDF-file hier! 


Enkel T, Spanagel R, Vollmayr B, Schneider M (2010) Stress Triggers Anhedonia in rats bred for learned helplessness. Behav Brain Res, 209, 183-186, als PDF-file hier! 

Enkel T, Gholizadeh D, von Bohlen Und Halbach O, Sanchis-Segura C, Hurlemann R, Spanagel R, Gass P, Vollmayr B. (2010) Ambiguous-cue interpretation is biased under stress- and depression-like states in rats. Neuropsychopharmacology 35:1008-1015, als PDF-file hier!  

Cippitelli A, Damadzic R, Hansson AC, Singley E, Sommer WH, Eskay R, Thorsell A, Heilig M (2010) Neuropeptide Y (NPY) suppresses yohimbine-induced reinstatement of alcohol seeking. Psychopharmacology (Berl.) 208:417-26, als PDF-file hier! 

Hansson AC, Nixon K, Rimondini R, Damadzic R, Sommer WH, Eskay R, Crews FT, Heilig M (2010) Long-term suppression of forebrain neurogenesis and loss of neuronal progenitor cells following prolonged alcohol dependence in rats. Int J Neuropsychopharmacol 13:583-93, als PDF-file hier! 

Björk K, Hansson AC, Sommer WH (2010) Genetic variation and brain gene expression in rodent models of alcoholism implications for medication development. Int Rev Neurobiol 91:129-71, als PDF-file hier! 

Sommer WH, Lidström J, Sun H, Passer D, Eskay R, Parker SC, Witt SH, Zimmermann US, Nieratschker V, Rietschel M, Margulies EH, Palkovits M, Laucht M, Heilig M (2010) Human NPY promoter variation rs16147:T>C as a moderator of prefrontal NPY gene expression and negative affect. Hum Mutat 31:E1594-608, als PDF-file hier!


Björk K, Terasmaa A, Sun H, Thorsell A, Sommer WH, Heilig M. Ethanol-inducedactivation of AKT and DARPP-32 in the mouse striatum mediated by opioid receptors. Addict Biol 15: 299-303, als PDF-file hier! 


Lindell SG, Schwandt ML, Sun H, Sparenborg JD, Björk K, Kasckow JW, Sommer WH, Goldman D, Higley JD, Suomi SJ, Heilig M, Barr CS (2010) Functional NPY variation as a factor in stress resilience and alcohol consumption in rhesus macaques. Arch Gen Psychiatry 67:423-31, als PDF-file hier! 

Heilig M, Thorsell A, Sommer WH, Hansson AC, Ramchandani VA, George DT, Hommer D, Barr CS (2010) Translating the neuroscience of alcoholism into clinical treatments: from blocking the buzz to curing the blues. Neurosci Biobehav Rev 35:334-44, als PDF-file hier! 

Sommer JU, Schmitt A, Heck M, Fendt M, Zink M, Nieselt K, Symons S, Petroianu G, Lex A, Herrera-Marschitz M, Spanagel R, Falkai P, Gebicke-Haerter PJ (2010) Differential expression of presynaptic genes in a rat model of postnatal hypoxia: relevance to schizophrenia. Eur Arch Psychiatry Clin Neurosci, Suppl 2:S81-9. Epub 2010 Oct 14, als PDF-file hier! 

Leweke FM, Schneider M (2010) Chronic pubertal cannabinoid treatment as a behavioural model for aspects of schizophrenia: effects of the atypical antipsychotic quetiapine. Int J Neuropsychopharmacol, 14:43-51, als PDF-file hier! 


Schmitt A, Leonardi-Essmann F, Durrenberger PF, Parlapani E, Schneider-Axmann T, Spanagel R, Arzberger T, Kretzschmar H, Herrera-Marschitz M, Gruber O, Reynolds R, Falkai P, Gebicke-Haerter PJ (2010) Regulation of immune-modulatory genes in left superior temporal cortex of schizophrenia patients: a genome-wide microarray study. World J Biol Psychiatry, in press 

Halbout B, Perreau-Lenz S, Dixon CI, Stephens DN, Spanagel R (2010) Per1Brdm1 mice do self-administer cocaine and reinstate cocaine-seeking behaviour. Behav Pharmacol, in press 

Halbout B, Spanagel R (2010) A single session of cocaine self-administration in mice supports the incubation of cocaine-seeking. Addict Biol, in press 

Schumann G, Loth E, Banaschewski T, Barker G, Büchel C, Conrod PF, Dalley JW, Flor H, Gallinat J, Garavan H, Heinz A, Itterman B, Lathrop M, Martinot JL, Mann K, Poline JB, Robbins TW, Rietschel M, Reed L, Smolka M, Spanagel R, Stephens DN, Stroehle A, Paus T, and the IMAGEN consortium (2010) The IMAGEN study: Reinforcement-related behaviour in normal brain function and psychopathology. Mol Psychiatry, 15:1128-39, als PDF-file hier!

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