The Unit’s research fields are the general, clinical and genetic epidemiology of and psychopathological/biological multi-level research into schizophrenia and schizophrenia spectrum disorders, including genetic aspects. All the research steps arising from the results of the ABC Schizophrenia Study (Project S1, funded by the German Research Association as part of the Special Research Branch 258 from 1987 to 1998 and as an independent project from 1999 to 2002) have been accomplished, including application of genetic-epidemiological approaches and development of strategies of predicting schizophrenia risk.
Main research topics
Protective effects of oestrogen. Oestrogen delays illness onset in premenopausal women and leads to a second peak of incidence and a significantly greater severity of illness in women than in men of the same age. The underlying neurobiological mechanism is a reduced sensitivity of central D2 receptors caused by oestrogen.
Controlled assessment of onset and early course of schizophrenia
Prospective investigation of medium-term course of schizophrenia
Ecological distribution of incidence, symptoms and course of schizophrenia
Causal associations of substance abuse and schizophrenia (in either direction)
A multi-level model of the determinants of the social course
Comparison of symptoms and risk factors in first-episode schizophrenia and related disorders across the life-cycle
Symposia
Symposium of the German Research Network on Schizophrenia Project Network 1: Early recognition and early intervention in psychosis. The German Psychiatric Association (DGPPN) Congress, Aachen, Sept. 20.-23, 2000
Early detection and intervention in psychosis, Section Symposium. 10th Congress of the Association of European Psychiatrists, Prague, Oct. 28 – Nov. 1, 2000
Antecedents and risk mechanisms of mental disorders during childhood and adolescence, Section Symposium. 10th Congress of the Association of European Psychiatrists, Prague, Oct. 28 – Nov. 1, 2000
Risk factors for psychoses, spectrum disorders and psychotic symptoms. 7th World Congress of Biological Psychiatry, Berlin, July 1 – 6, 2000
Early detection of psychosis. The Royal College of Psychiatrists Annual Meeting/WPA Meeting, London, July 9 – 13, 2001
Risk and protective factors in schizophrenia - towards a conceptual model of the disease process. Heidelberg, Oct. 25 – 27, 2001
Is early intervention feasible: Pre-psychosis identification, 11th Biennial Winter Workshop on Schizophrenia, Davos, Feb 24 - March 1, 2002
Gender differences in major mental disorder, Section symposium, 11th AEP Congress, Stockholm, Sweden, May 4-8, 2002
Early detection of mental disorders, XII World Congress of Psychiatry, Yokohama, Aug. 24-29, 2002
Biological risk factors and prodromi of schiziphrenia, XII World Congress of Psychiatry, Yokohama, Aug. 24-29, 2002
Early detection, recognition and intervention in schizophrenia, 3rd International Conference on Early Psychosis (IEPA), Copenhagen, Sept. 24-28, 2002
Der natürliche Verlauf der Schizophrenie - von Ausbruch bis Outcome, DGPPN Kongress, Berlin, 27.11.-1.12.2002
Risikopopulationen, Kongreß über süchtige Kinder und Jugendliche - Prävention und Therapie des Substanzmißbrauchs, Hamburg, 19.-21.2.2003
5th Search for the causes of schizophrenia (Gattaz/Häfner), Guarujá, Brasilia, Apr 8-12, 2003
Depression und Schizophrenie, DGPPN Kongress, Berlin, 19.-22.11.2003
Risk and protective factors for schizophrenia, 12th AEP Congress, Geneve, Apr. 14-18, 2004
Depression und Psychose - Risikodimensionen, Verlaufsstadien oder zwei Krankheiten. DGPPN Kongress Berlin, 24.-27.11.2004
New challenges to the dichotomy schizophrenia versus affective disorder, 13th AEP Congress, Munich, Apr. 1-6, 2005
Sigmund Freud und die Psychoanalyse - Blick zurück und voraus, DGPPN Kongress, Berlin 22.-25.11.2006
Neurobiologische Mechanismen und Psychoserisiko. DGPPN Kongress, Berlin, 21.-24-11.2007
Berufliche Identität und Rollenverständnis des Psychiaters heute. Pro-Con-Debatte. DGPPN-Kongress, Berlin, 26.-29.11.2008
Früherkennung und Frühintervention bei schizophrenen Störungen: Entwicklungsstand und Anwendungsperspektiven. DGPPN-Kongress, Berlin, 25.-28.11.2009
associated with the Centre for Epidemiology and Services Research
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