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Publikationen: Psychopharmakologie

Becker A, Gerchen MF, Kirsch M, Ubl B, Subramaniapillai S, Diener C, Kühner C, Kiefer F, Kirsch P. Frontostriatal connectivity during reward anticipation. Z Psychol. 2017 225(3):232-243.
Berberich S, Pohle J, Pollard M, Barroso-Flores J, Köhr G. Interplay between global and pathway-specific synaptic plasticity in CA1 pyramidal cells. Sci Rep. 2017 7(1):17040.
Bernardi RE, Broccoli L, Hirth N, Justice NJ, Deussing JM, Hansson AC, Spanagel R. Dissociable Role of Corticotropin Releasing Hormone Receptor Subtype 1 on Dopaminergic and D1 Dopaminoceptive Neurons in Cocaine Seeking Behavior. Front Behav Neurosci. 2017 11:221.
Bourque J, Spechler PA, Potvin S, Whelan R, Banaschewski T, Bokde AL, Bromberg U, Büchel C, Quinlan EB, Desrivieres S, Flor H, Frouin V, Gowland P, Heinz A, Ittermann B, Martinot JL, Paillere-Martinot ML, McEwen SC, Nees F, Orfanos DP, Paus T, Poustka L, Smolka MN, Vetter NC, Walter H, Schumann G, Garavan H, Conrod PJ, Mann K, Rietschel M, Spanagel R, Fauth-Bühler M, Millenet S, Grimmer Y, IMAGEN Consortium . Functional Neuroimaging Predictors of Self-Reported Psychotic Symptoms in Adolescents. Am J Psychiatry. 2017 174(6):566-575. Epub 2017 Mar 21.
Bröker-Lai J, Kollewe A, Schindeldecker B, Pohle J, Nguyen Chi V, Mathar I, Guzman R, Schwarz Y, Lai A, Weißgerber P, Schwegler H, Dietrich A, Both M, Sprengel R, Draguhn A, Köhr G, Fakler B, Flockerzi V, Bruns D, Freichel M. Heteromeric channels formed by TRPC1, TRPC4 and TRPC5 define hippocampal synaptic transmission and working memory. EMBO J. 2017 36(18)::2770-2789. Epub 2017 Aug 8.
Bumb JM, Kiefer F. Alkoholabhängigkeit im Wandel - was hat sich verändert?. Spectrum. Psychiatrie. 2017 19(6)
Bumb JM, Kiefer F. Nutzen von Stimulanzien zur kognitiven Leistungssteigerung fraglich. Kommentar zu "Stimulanzien verbessern Entscheidungsfindung - zumindest wenn Zeit keine Rolle spielt". InFo Neurol & Psychiatr. 2017 19(6):21.
Büchel C, Peters J, Banaschewski T, Bokde AL, Bromberg U, Conrod PJ, Flor H, Papadopoulos D, Garavan H, Gowland P, Heinz A, Walter H, Ittermann B, Mann K, Martinot JL, Paillere-Martinot ML, Nees F, Paus T, Pausova Z, Poustka L, Rietschel M, Robbins TW, Smolka MN, Gallinat J, Schumann G, Knutson B, Spanagel R, Fauth-Bühler M, Millenet S, Grimmer Y, IMAGEN consortium . Blunted ventral striatal responses to anticipated rewards foreshadow problematic drug use in novelty-seeking adolescents. Nat Commun. 2017 8:14140.
Cannella N, Cosa-Linan A, Roscher M, Takahashi TT, Vogler N, Wängler B, Spanagel R. [18F]-Fluorodeoxyglucose-Positron Emission Tomography in Rats with Prolonged Cocaine Self-Administration Suggests Potential Brain Biomarkers for Addictive Behavior. Front Psychiatry. 2017 8:218.
Cosa A, Moreno A, Pacheco-Torres J, Ciccocioppo R, Hyytiä P, Sommer WH, Moratal D, Canals S. Multi-modal MRI classifiers identify excessive alcohol consumption and treatment effects in the brain. Addict Biol. 2017 22(5):1459-1472. Epub 2016 Jun 8.
Filipovic D, Todorović N, Bernardi RE, Gass P. Oxidative and nitrosative stress pathways in the brain of socially isolated adult male rats demonstrating depressive- and anxiety-like symptoms. Brain Struct Funct. 2017 222(1):1-20. Epub 2016 Mar 31.
Foo JC, Noori HR, Yamaguchi I, Vengeliene V, Cosa-Linan A, Nakamura T, Morita K, Spanagel R, Yamamoto Y. Dynamical state transitions into addictive behaviour and their early-warning signals. Proc Biol Sci. 2017 284(1860)
Frischknecht U, Hermann D, Tunc-Skarka N, Wang GY, Sack MS, van Eijk J, Demirakca T, Falfán-Melgoza C, Krumm B, Dieter S, Spanagel R, Kiefer F, Mann KF, Sommer WH, Ende G, Weber-Fahr W. Negative Association Between MR-Spectroscopic Glutamate Markers and Gray Matter Volume After Alcohol Withdrawal in the Hippocampus: A Translational Study in Humans and Rats. Alcohol Clin Exp Res. 2017 41(2):323-333.
Gispert JD, Figueiras FP, Vengeliene V, Herance JR, Rojas S, Spanagel R. Changes in cerebral [(18)F]-FDG uptake induced by acute alcohol administration in a rat model of alcoholism. Behav Brain Res. 2017 327:29-33. Epub 2017 Mar 27.
Goepfrich AA, Friemel CM, Pauen S, Schneider M. Ontogeny of sensorimotor gating and short-term memory processing throughout the adolescent period in rats. Dev Cogn Neurosci. 2017 25:167-175. Epub 2016 Nov 19.
Hadar R, Voget M, Vengeliene V, Haumesser JK, van Riesen C, Avchalumov Y, Spanagel R, Winter C. Altered neural oscillations and elevated dopamine levels in the reward pathway during alcohol relapse. Behav Brain Res. 2017 316:131-135. Epub 2016 Aug 25.
Heilig M, Barbier E, Johnstone AL, Tapocik J, Meinhardt MW, Pfarr S, Wahlestedt CR, Sommer WH. Reprogramming of mPFC transcriptome and function in alcohol dependence. Genes Brain Behav. 2017 16(1):86-100. Epub 2016 Sep 22.
Hermann D, Hirth N, Reimold M, Batra A, Smolka MN, Hoffmann S, Kiefer F, Noori HR, Sommer WH, Reischl G, la Fougère C, Mann K, Spanagel R, Hansson AC. Low μ-Opioid Receptor Status in Alcohol Dependence Identified by Combined Positron Emission Tomography and Post-Mortem Brain Analysis. Neuropsychopharmacology. 2017 42(3):6063-614. Epub 2016 Aug 11.
Juhás M, Sun H, Brown MR, MacKay MB, Mann KF, Sommer WH, Wilman AH, Dursun SM, Greenshaw AJ. Deep Grey Matter Iron Accumulation in Alcohol Use Disorder. Neuroimage. 2017 148:115-122. Epub 2017 Jan 5.
Khan W, Giampietro V, Banaschewski T, Barker GJ, Bokde AL, Büchel C, Conrod P, Flor H, Frouin V, Garavan H, Gowland P, Heinz A, Ittermann B, Lemaitre H, Nees F, Paus T, Pausova Z, Rietschel M, Smolka MN, Ströhle A, Gallinat J, Vellas B, Soininen H, Kloszewska I, Tsolaki M, Mecocci P, Spenger C, Villemagne VL, Masters CL, Muehlboeck JS, Bäckman L, Fratiglioni L, Kalpouzos G, Wahlund LO, Schumann G, Lovestone S, Williams SC, Westman E, Simmons A, Alzheimer–s Disease Neuroimaging Initiative , AddNeuroMed Consortium, Australian, Imaging, Biomarkers, and Lifestyle Study Research Group , Spanagel R, Fauth-Bühler M, Millenet S, Grimmer Y, IMAGEN consortium . A Multi-Cohort Study of ApoE ɛ4 and Amyloid-β Effects on the Hippocampus in Alzheimer's Disease. J Alzheimers Dis. 2017 56(3):1159-1174.
Lett TA, Waller L, Tost H, Veer IM, Nazeri A, Erk S, Brandl EJ, Charlet K, Beck A, Vollstädt-Klein S, Jorde A, Kiefer F, Heinz A, Meyer-Lindenberg A, Chakravarty MM, Walter H. Cortical surface-based threshold-free cluster enhancement and cortexwise mediation. Hum Brain Mapp. 2017 38(6):2795-2807. Epub 2017 Mar 20.
Lissek T, Adams M, Adelman J, Ahissar E, Akaaboune M, Akil H, Al'absi M, Arain F, Arango-Lasprilla JC, Atasoy D, Avila J, Badawi A, Bading H, Baig AM, Baleriola J, Belmonte C, Bertocchi I, Betz H, Blakemore C, Blanke O, Boehm-Sturm P, Bonhoeffer T, Bonifazi P, Brose N, Campolongo P, Celikel T, Chang CC, Chang TY, Citri A, Cline HT, Cortes JM, Cullen K, Dean K, Delgado-Garcia JM, Desroches M, Disterhoft JF, Dowling JE, Draguhn A, El-Khamisy SF, El Manira A, Enam SA, Encinas JM, Erramuzpe A, Esteban JA, Fariñas I, Fischer E, Fukunaga I, Gabilondo I, Ganten D, Gidon A, Gomez-Esteban JC, Greengard P, Grinevich V, Gruart A, Guillemin R, Hariri AR, Hassan B, Häusser M, Hayashi Y, Hussain NK, Jabbar AA, Jaber M, Jahn R, Janahi EM, Kabbaj M, Kettenmann H, Kindt M, Knafo S, Köhr G, Komai S, Krugers H, Kuhn B, Ghazal NL, Larkum ME, London M, Lutz B, Matute C, Martinez-Millan L, Maroun M, McGaugh J, Moustafa AA, Nasim A, Nave KA, Neher E, Nikolich K, Outeiro T, Palmer LM, Penagarikano O, Perez-Otano I, Pfaff DW, Poucet B, Rahman AU, Ramos-Cabrer P, Rashidy-Pour A, Roberts RJ, Rodrigues S, Sanes JR, Schaefer AT, Segal M, Segev I, Shafqat S, Siddiqui NA, Soreq H, Soriano-García E, Spanagel R, Sprengel R, Stuart G, Südhof TC, Tønnesen J, Treviño M, Uthman BM, Venter JC, Verkhratsky A, Weiss C, Wiesel TN, Yaksi E, Yizhar O, Young LJ, Young P, Zawia NH, Zugaza JL, Hasan MT. Building Bridges through Science. Neuron. 2017 96(4):730-735.
Luis C, Cannella N, Spanagel R, Köhr G. Persistent strengthening of the prefrontal cortex - nucleus accumbens pathway during incubation of cocaine-seeking behavior. Neurobiol Learn Mem. 2017 138:281-290. Epub 2016 Oct 5.
Mackey S, Chaarani B, Kan KJ, Spechler PA, Orr C, Banaschewski T, Barker G, Bokde AL, Bromberg U, Büchel C, Cattrell A, Conrod PJ, Desrivieres S, Flor H, Frouin V, Gallinat J, Gowland P, Heinz A, Ittermann B, Paillère Martinot ML, Artiges E, Nees F, Papadopoulos-Orfanos D, Poustka L, Smolka MN, Jurk S, Walter H, Whelan R, Schumann G, Althoff RR, Garavan H, Vollstädt-Klein S, Rietschel M, Schulze TG, Spanagel R, Diesch E, Gebicke-Haerter PJ, Kiefer F, Fauth-Bühler M, Millenet S, Grimmer Y, IMAGEN Consortium . Brain Regions Related to Impulsivity Mediate the Effects of Early Adversity on Antisocial Behavior. Biol Psychiatry. 2017 82(4):275-282. Epub 2016 Jan 18.
Noori HR, Schöttler J, Ercsey-Ravasz M, Cosa-Linan A, Varga M, Toroczkai Z, Spanagel R. A multiscale cerebral neurochemical connectome of the rat brain. PLoS Biol. 2017 15(7):e2002612.
Perreau-Lenz SP, Hoelters LS, Leixner S, Sanchis-Segura C, Hansson A, Bilbao A, Spanagel R. mPer1 promotes morphine-induced locomotor sensitization and conditioned place preference via histone deacetylase activity. Psychopharmacology (Berl). 2017 234(11):1713-1724. Epub 2017 Feb 28.
Quinlan EB, Cattrell A, Jia T, Artiges E, Banaschewski T, Barker G, Bokde AL, Bromberg U, Büchel C, Brühl R, Conrod PJ, Desrivieres S, Flor H, Frouin V, Gallinat J, Garavan H, Gowland P, Heinz A, Martinot JL, Paillère Martinot ML, Nees F, Papadopoulos-Orfanos D, Paus T, Poustka L, Smolka MN, Vetter NC, Walter H, Whelan R, Glennon JC, Buitelaar JK, Happé F, Loth E, Barker ED, Schumann G, Rietschel M, Spanagel R, Millenet S, Fauth-Bühler M, Grimmer Y, IMAGEN Consortium . Psychosocial Stress and Brain Function in Adolescent Psychopathology. Am J Psychiatry. 2017 174(8):785-794. Epub 2017 Jun 16.
Rivera A, Gago B, Suárez-Boomgaard D, Yoshitake T, Roales-Buján R, Valderrama-Carvajal A, Bilbao A, Medina-Luque J, Díaz-Cabiale Z, Craenenbroeck KV, Borroto-Escuela DO, Kehr J, Rodríguez de Fonseca F, Santín L, de la Calle A, Fuxe K. Dopamine D4 receptor stimulation prevents nigrostriatal dopamine pathway activation by morphine: relevance for drug addiction. Addict Biol. 2017 22(5):1232-1245. Epub 2016 May 22.
Rotermund C, Reolon GK, Leixner S, Boden C, Bilbao A, Kahle PJ. Enhanced motivation to alcohol in transgenic mice expressing human α-synuclein. J Neurochem. 2017 143(3):294-305. Epub 2017 Aug 21.
Schneider M, Levant B, Reichel M, Gulbins E, Kornhuber J, Müller CP. Lipids in psychiatric disorders and preventive medicine. Neurosci Biobehav Rev. 2017 76(Pt B):336-362. Epub 2016 Jun 16.
Schneider M, Reininghaus U, van Nierop M, Janssens M, Myin-Germeys I, GROUP Investigators . Does the Social Functioning Scale reflect real-life social functioning? An experience sampling study in patients with a non-affective psychotic disorder and healthy control individuals. Psychol Med. 2017 47(16):2777-2786.
Schneider M, de Vries PJ, Schönig K, Rößner V, Waltereit R. mTOR inhibitor reverses autistic-like social deficit behaviours in adult rats with both Tsc2 haploinsufficiency and developmental status epilepticus. Eur Arch Psychiatry Clin Neurosci. 2017 267(5):455-463. Epub 2016 Jun 4.
Schuster R, Koopmann A, Grosshans M, Reinhard I, Spanagel R, Kiefer F. Association of plasma calcium concentrations with alcohol craving: New data on potential pathways. Eur Neuropsychopharmacol. 2017 27(1):42-47. Epub 2016 Nov 24.
Shimshek DR, Bus T, Schupp B, Jensen V, Marx V, Layer LE, Köhr G, Sprengel R. Different Forms of AMPA Receptor Mediated LTP and Their Correlation to the Spatial Working Memory Formation. Front Mol Neurosci. 2017 10:214.
Spanagel R. Animal models of addiction. Dialogues Clin Neurosci. 2017 19(3):247-258.
Spanagel R. Mechanismen der Suchtentwicklung. Drug Res (Stuttg). 2017 67(S 01):S17.
Spanagel R, Kiefer F. The Cannabinoid Receptor 1 as a Key Mediator of Adolescent Behavior. Neuropsychopharmacology. 2017 42(1):367.
Takahashi TT, Vengeliene V, Spanagel R. Melatonin reduces motivation for cocaine self-administration and prevents relapse-like behavior in rats. Psychopharmacology (Berl). 2017 234(11):1741-1748. Epub 2017 Feb 28.
Treutlein J, Frank J, Streit F, Reinbold CS, Juraeva D, Degenhardt F, Rietschel L, Witt SH, Forstner AJ, Ridinger M, Strohmaier J, Wodarz N, Dukal H, Foo JC, Hoffmann P, Herms S, Heilmann-Heimbach S, Soyka M, Maier W, Gaebel W, Dahmen N, Scherbaum N, Müller-Myhsok B, Lucae S, Ising M, Stickel F, Berg T, Roggenbuck U, Jöckel KH, Scholz H, Zimmermann US, Buch S, Sommer WH, Spanagel R, Brors B, Cichon S, Mann K, Kiefer F, Hampe J, Rosendahl J, Nöthen MM, Rietschel M. Genetic Contribution to Alcohol Dependence: Investigation of a Heterogeneous German Sample of Individuals with Alcohol Dependence, Chronic Alcoholic Pancreatitis, and Alcohol-Related Cirrhosis. Genes (Basel). 2017 8(7)
Uhrig S, Vandael D, Marcantoni A, Dedic N, Bilbao A, Vogt MA, Hirth N, Broccoli L, Bernardi RE, Schönig K, Gass P, Bartsch D, Spanagel R, Deussing JM, Sommer WH, Carbone E, Hansson AC. Differential Roles for L-Type Calcium Channel Subtypes in Alcohol Dependence. Neuropsychopharmacology. 2017 42(5):1058-1069. Epub 2016 Dec 1.
Vengeliene V, Bespalov A, Roßmanith M, Horschitz S, Berger S, Relo AL, Noori HR, Schneider P, Enkel T, Bartsch D, Schneider M, Behl B, Hansson AC, Schloss P, Spanagel R. Towards trans-diagnostic mechanisms in psychiatry: Neurobehavioral profile of rats with a loss of function point mutation in the dopamine transporter gene. Dis Model Mech. 2017 104(4):451-461. Epub 2017 Feb 6.


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