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Publikationen: Psychopharmakologie

Allende-Castro C, Espina-Marchant P, Bustamante D, Rojas-Mancilla E, Neira T, Gutierrez-Hernandez MA, Esmar D, Valdes JL, Morales P, Gebicke-Haerter PJ, Herrera-Marschitz M. Further Studies on the Hypothesis of PARP-1 Inhibition as a Strategy for Lessening the Long-Term Effects Produced by Perinatal Asphyxia: Effects of Nicotinamide and Theophylline on PARP-1 Activity in Brain and Peripheral Tissue : Nicotinamide and Theophyl. Neurotox Res. 2012 22(1):79-90. Epub 2012 Feb 4.
Amy M, Staehlin O, René F, Blasco H, Marouillat S, Daoud H, Vourc'h P, Gordon PH, Camu W, Corcia P, Loeffler JP, Palkovits M, Sommer WH, Andres CR. A common functional allele of the Nogo receptor gene, reticulon 4 receptor (RTN4R), is associated with sporadic amyotrophic lateral sclerosis in a French population. Amyotroph Lateral Scler Frontotemporal Degener. 2015 16(7-8):490-6.
Andreescu CE, Prestori F, Brandalise F, D'Errico A, De Jeu MT, Rossi P, Botta L, Köhr G, Perin P, D'Angelo E, De Zeeuw CI. NR2A subunit of the N-methyl D-aspartate receptors are required for potentiation at the mossy fiber to granule cell synapse and vestibulo-cerebellar motor learning. Neuroscience. 2011 176:274-83.
Astori S, Pawlak V, Köhr G. Spike-timing-dependent plasticity in hippocampal CA3 neurons. J Physiol. 2010 588(Pt 22):4475-88.
Bach P, Vollstädt-Klein S, Kirsch M, Hoffmann S, Jorde A, Frank J, Charlet K, Beck A, Heinz A, Walter H, Sommer WH, Spanagel R, Rietschel M, Kiefer F. Increased mesolimbic cue-reactivity in carriers of the mu-opioid-receptor gene OPRM1 A118G polymorphism predicts drinking outcome: A functional imaging study in alcohol dependent subjects. Eur Neuropsychopharmacol. 2015 25(8):1128-35. Epub 2015 Apr 18.
Bacon C, Schneider M, Le Magueresse C, Froehlich H, Sticht C, Gluch C, Monyer H, Rappold GA. Brain-specific Foxp1 deletion impairs neuronal development and causes autistic-like behaviour. Mol Psychiatry. 2015 20(5):632-9. Epub 2014 Sep 30.
Ballesteros JJ, Buschler A, Köhr G, Manahan-Vaughan D. Afferent Input Selects NMDA Receptor Subtype to Determine the Persistency of Hippocampal LTP in Freely Behaving Mice. Front Synaptic Neurosci. 2016 8:33.
Barr CS, Dvoskin RL, Gupte M, Sommer W, Sun H, Schwandt ML, Lindell SG, Kasckow JW, Suomi SJ, Goldman D, Higley JD, Heilig M. Functional CRH variation increases stress-induced alcohol consumption in primates. Proc Natl Acad Sci U S A. 2009 106(34):14593-8.
Bartoi T, Rigbolt KT, Du D, Köhr G, Blagoev B, Kornau HC. GABAB receptor constituents revealed by tandem affinity purification from transgenic mice. J Biol Chem. 2010 285(27):20625-33.
Bauhofer A, Ho YJ, Schmitt A, Köster M, Schwarting RK, Pawlak CR. Individual behavioral differences in recovery from abdominal sepsis in rats. Inflamm Res. 2009 58(5):248-56.
Berberich S, Punnakkal P, Jensen V, Pawlak V, Seeburg PH, Hvalby Ø, Köhr G. Lack of NMDA receptor subtype selectivity for hippocampal long-term potentiation. J Neurosci. 2005 25(29):6907-10.
Berger SM, Weber T, Perreau-Lenz SP, Vogt MA, Gartside SE, Maser-Gluth C, Lanfumey L, Gass P, Spanagel R, Bartsch D. A Functional Tph2 C1473G Polymorphism Causes an Anxiety Phenotype via Compensatory Changes in the Serotonergic System. Neuropsychopharmacology. 2012 37(9):1986-98. Epub 2012 Apr 11.
Bernardi RE. Advances in nicotine research in Addiction Biology. Addict Biol. 2015 20(5):877-89.
Bernardi RE, Broccoli L, Spanagel R, Hansson AC. Sex differences in dopamine binding and modafinil conditioned place preference in mice. Drug Alcohol Depend. 2015 155:37-44. Epub 2015 Aug 28.
Bernardi RE, Lattal KM. Prazosin differentially affects extinction of cocaine conditioned place preference on the basis of dose and initial preference. Neuroreport. 2012 23(18):1048-51.
Bernardi RE, Lattal KM. Post-conditioning propranolol disrupts cocaine sensitization. Pharmacol Biochem Behav. 2012 102(4):515-9.
Bernardi RE, Spanagel R. Basal Activity Level in Mice Predicts the Initial and Sensitized Locomotor Response to Nicotine Only in High Responders. Behav Brain Res. 2014 264:143-50. Epub 2014 Feb 4.
Bernardi RE, Spanagel R. A two-injection protocol for nicotine sensitization. Behav Brain Res. 2014 275:11-4. Epub 2014 Sep 1.
Bernardi RE, Spanagel R. The ClockΔ19 mutation in mice fails to alter the primary and secondary reinforcing properties of nicotine. Drug Alcohol Depend. 2013 133(2):733-9. Epub 2013 Sep 5.
Bernardi RE, Spanagel R. Enhanced Extinction of Contextual Fear Conditioning in ClockΔ19 Mutant Mice. Behav Neurosci. 2014 128(4):468-73. Epub 2014 May 26.
Bernardi RE, Uhrig S, Spanagel R, Hansson AC. The Transcriptional Regulation of L-Type Calcium Channel Subtypes Cav1.2 and Cav1.3 by Nicotine and Their Potential Role in Nicotine Sensitization. Nicotine Tob Res. 2014 16(6):774-85. Epub 2014 Jan 29.
Bernardi RE, Zohsel K, Hirth N, Treutlein J, Heilig M, Laucht M, Spanagel R, Sommer WH. A gene-by-sex interaction for nicotine reward: evidence from humanized mice and epidemiology. Transl Psychiatry. 2016 6(7):e861.
Bilbao A, Blanco E, Luque-Rojas MJ, Suárez J, Palomino A, Vida M, Araos P, Bermúdez-Silva FJ, Fernández-Espejo E, Spanagel R, Rodríguez de Fonseca F. Oleoylethanolamide dose-dependently attenuates cocaine-induced behaviours through a PPAR? receptor-independent mechanism. Addict Biol. 2013 18(1):78-87. Epub 2012 Nov 19..
Bilbao A, Parkitna JR, Engblom D, Perreau-Lenz SP, Sanchis-Segura C, Schneider M, Konopka W, Westphal M, Breen G, Desrivieres S, Klugmann M, Guindalini C, Vallada H, Laranjeira R, de Fonseca FR, Schumann G, Schütz G, Spanagel R. Loss of the Ca2+/calmodulin-dependent protein kinase type IV in dopaminoceptive neurons enhances behavioral effects of cocaine. Proc Natl Acad Sci U S A. 2008 105(45):17549-54.
Bilbao A, Rieker C, Cannella N, Parlato R, Golda S, Piechota M, Korostynski M, Engblom D, Przewlocki R, Schütz G, Spanagel R, Parkitna JR. CREB activity in dopamine D1 receptor expressing neurons regulates cocaine-induced behavioral effects. Front Behav Neurosci. 2014 8:212.
Bilbao A, Rieker C, Cannella N, Parlato R, Golda S, Piechota M, Korostynski M, Engblom D, Przewlocki R, Schütz G, Spanagel R, Rodriguez Parkitna J. Corrigendum: CREB activity in dopamine D1 receptor expressing neurons regulates cocaine-induced behavioral effects. Front Behav Neurosci. 2014 8:239.
Bilbao A, Robinson JE, Heilig M, Malanga CJ, Spanagel R, Sommer WH, Thorsell A. A Pharmacogenetic Determinant of Mu-Opioid Receptor Antagonist Effects on Alcohol Reward and Consumption: Evidence from Humanized Mice. Biol Psychiatry. 2015 77(10):850-8. Epub 2014 Sep 8.
Bilbao A, Serrano A, Cippitelli A, Pavón FJ, Giuffrida A, Suárez J, García-Marchena N, Baixeras E, Gómez de Heras R, Orio L, Alén F, Ciccocioppo R, Cravatt BF, Parsons LH, Piomelli D, Rodríguez de Fonseca F. Role of the satiety factor oleoylethanolamide in alcoholism. Addict Biol. 2016 21(4):859-72. Epub 2015 Jun 2.
Björk K, Hansson AC, Sommer WH. Genetic variation and brain gene expression in rodent models of alcoholism implications for medication development. Int Rev Neurobiol. 2010 91:129-71.
Björk K, Terasmaa A, Sun H, Thorsell A, Sommer WH, Heilig M. Ethanol-induced activation of AKT and DARPP-32 in the mouse striatum mediated by opioid receptors. Addict Biol. 2010 15(3):299-303.
Björk K, Tronci V, Thorsell A, Tanda G, Hirth N, Heilig M, Hansson AC, Sommer WH. β-Arrestin 2 knockout mice exhibit sensitized dopamine release and increased reward in response to a low dose of alcohol. Psychopharmacology (Berl). 2013 230(3):439-49. Epub 2013 Jun 19.
Blanco E, Galeano P, Palomino A, Pavón FJ, Rivera P, Serrano A, Alén F, Rubio L, Vargas A, Castilla-Ortega E, Decara J, Bilbao A, de Fonseca FR, Suárez J. Cocaine-induced behavioral sensitization decreases the expression of endocannabinoid signaling-related proteins in the mouse hippocampus. Eur Neuropsychopharmacol. 2016 26(3):477-92. Epub 2016 Jan 7.
Blomeyer D, Friemel CM, Buchmann AF, Banaschewski T, Laucht M, Schneider M. Impact of Pubertal Stage at First Drink on Adult Drinking Behavior. Alcohol Clin Exp Res. 2013 37(10):1804-11. Epub 2013 May 17.
Bottlender M, Spanagel R, Soyka M. [One drink, one drunk- Ist kontrolliertes Trinken möglich?. Psychother Psychosom Med Psychol. 2007 57(1):32-8.
Brand I, Fliegel S, Spanagel R, Noori HR. Global Ethanol-Induced Enhancements of Monoaminergic Neurotransmission: A Meta-Analysis Study. Alcohol Clin Exp Res. 2013 37(12):2048-57. Epub 2013 Jun 28.
Brand T, Spanagel R, Schneider M. Decreased reward sensitivity in rats from the fischer344 strain compared to wistar rats is paralleled by differences in endocannabinoid signaling. PLoS ONE. 2012 7(2):e31169.
Brunk I, Blex C, Sanchis-Segura C, Sternberg J, Perreau-Lenz SP, Bilbao A, Hörtnagl H, Baron J, Juranek J, Laube G, Birnbaumer L, Spanagel R, Ahnert-Hilger G. Deletion of Go2alpha abolishes cocaine-induced behavioral sensitization by disturbing the striatal dopamine system. FASEB J. 2008 22(10):3736-46.
Brunk I, Sanchis-Segura C, Blex C, Perreau-Lenz SP, Bilbao A, Spanagel R, Ahnert-Hilger G. Amphetamine regulates NR2B expression in Go2alpha knockout mice and thereby sustains behavioral sensitization. J Neurochem. 2010 115(1):234-46. doi: 10.1111/j.1471-4159.2010.06921.x. Epub 2010 Aug 12.
Burt KB, Whelan R, Conrod PJ, Banaschewski T, Barker GJ, Bokde AL, Bromberg U, Büchel C, Fauth-Bühler M, Flor H, Galinowski A, Gallinat J, Gowland P, Heinz A, Ittermann B, Mann K, Nees F, Papadopoulos-Orfanos D, Paus T, Pausova Z, Poustka L, Rietschel M, Robbins TW, Smolka MN, Ströhle A, Schumann G, Garavan H, Diesch E, Gebicke-Haerter PJ, Kiefer F, Vollstädt-Klein S, Schulze TG, Spanagel R, IMAGEN Consortium . Structural brain correlates of adolescent resilience. J Child Psychol Psychiatry. 2016 57(11):1287-1296. Epub 2016 Apr 15.
Cannella N, Halbout B, Uhrig S, Evrard L, Corsi M, Corti C, Deroche-Gamonet V, Hansson AC, Spanagel R. The mGluR2/3 agonist LY379268 induced anti-reinstatement effects in rats exhibiting addiction-like behavior. Neuropsychopharmacology. 2013 38(10):2048-56. Epub 2013 Apr 29.
Cannella N, Kallupi M, Ruggeri B, Ciccocioppo R, Ubaldi M. The role of the neuropeptide S system in addiction: focus on its interaction with the CRF and hypocretin/orexin neurotransmission. Prog Neurobiol. 2013 100:48-59.
Chourbaji S, Urani A, Inta I, Sanchis-Segura C, Brandwein C, Zink M, Schwaninger M, Gass P. IL-6 knockout mice exhibit resistance to stress-induced development of depression-like behaviors. Neurobiol Dis. 2006 23(3):587-94.
Ciccocioppo R, de Guglielmo G, Hansson AC, Ubaldi M, Kallupi M, Cruz MT, Oleata CS, Heilig M, Roberto M. Restraint Stress Alters Nociceptin/Orphanin FQ and CRF Systems in the Rat Central Amygdala: Significance for Anxiety-Like Behaviors. J Neurosci. 2014 34(2):363-72.
Cippitelli A, Damadzic R, Hansson AC, Singley E, Sommer WH, Eskay R, Thorsell A, Heilig M. Neuropeptide Y (NPY) suppresses yohimbine-induced reinstatement of alcohol seeking. Psychopharmacology (Berl). 2010 208(3):417-26. Epub 2009 Dec 10.
Cleppien DC, Sartorius A, Gass N, Noori HR, Weber-Fahr W. P.1.e.008 High-resolution regional cerebral blood volume mapping by using pharmacological high-filed magnetic resonance imaging. Eur Neuropsychopharmacol. 2011 21:S307-S308.
Cury C, Toro R, Cohen F, Fischer C, Mhaya A, Samper-González J, Hasboun D, Mangin JF, Banaschewski T, Bokde AL, Bromberg U, Buechel C, Cattrell A, Conrod P, Flor H, Gallinat J, Garavan H, Gowland P, Heinz A, Ittermann B, Lemaitre H, Martinot JL, Nees F, Paillère Martinot ML, Orfanos DP, Paus T, Poustka L, Smolka MN, Walter H, Whelan R, Frouin V, Schumann G, Glaunès JA, Colliot O, Diesch E, Gebicke-Härter PJ, Kiefer F, Vollstädt-Klein S, Rietschel M, Schulze TG, Spanagel R, IMAGEN Consortium . Incomplete Hippocampal Inversion: A Comprehensive MRI Study of Over 2000 Subjects. Front Neuroanat. 2015 9:160.
Degenhardt F, Krämer L, Frank J, Treutlein J, Heilmann-Heimbach S, Hecker J, Fier HL, Lang M, Witt SH, Koller AC, Mann K, Hoffmann S, Kiefer F, Spanagel R, Rietschel M, Nöthen MM. Analysis of Rare Variants in the Alcohol Dependence Candidate Gene GATA4. Alcohol Clin Exp Res. 2016 40(8):1627-32. Epub 2016 Jul 4.
Dell'acqua F, Khan W, Gottlieb N, Giampietro V, Ginestet C, Bouls D, Newhouse S, Dobson R, Banaschewski T, Barker GJ, Bokde AL, Büchel C, Conrod P, Flor H, Frouin V, Garavan H, Gowland P, Heinz A, Lemaitre H, Nees F, Paus T, Pausova Z, Rietschel M, Smolka MN, Ströhle A, Gallinat J, Westman E, Schumann G, Lovestone S, Simmons A, Vollstädt-Klein S, Grimmer Y, Millenet S, Fauth-Bühler M, Spanagel R, The IMAGEN Consortium . Tract Based Spatial Statistic Reveals No Differences in White Matter Microstructural Organization between Carriers and Non-Carriers of the APOE ɛ4 and ɛ2 Alleles in Young Healthy Adolescents. J Alzheimers Dis. 2015 47(4):977-84.
Desrivieres S, Lourdusamy A, Tao C, Toro R, Jia T, Loth E, Medina LM, Kepa A, Fernandes A, Ruggeri B, Carvalho FM, Cocks G, Banaschewski T, Barker GJ, Bokde AL, Büchel C, Conrod PJ, Flor H, Heinz A, Gallinat J, Garavan H, Gowland P, Brühl R, Lawrence C, Mann K, Martinot ML, Nees F, Lathrop M, Poline JB, Rietschel M, Thompson P, Fauth-Bühler M, Smolka MN, Pausova Z, Paus T, Feng J, Schumann G, Vollstädt-Klein S, Spanagel R, Millenet S, Grimmer Y, The IMAGEN Consortium . Single nucleotide polymorphism in the neuroplastin locus associates with cortical thickness and intellectual ability in adolescents. Mol Psychiatry. 2015 20(2):263-74. Epub 2014 Feb 11.
Dickie EW, Tahmasebi A, French L, Kovacevic N, Banaschewski T, Barker GJ, Bokde A, Büchel C, Conrod P, Flor H, Garavan H, Gallinat J, Gowland P, Heinz A, Ittermann B, Lawrence C, Mann K, Martinot JL, Nees F, Nichols T, Lathrop M, Loth E, Pausova Z, Rietschel M, Smolka MN, Ströhle A, Toro R, Schumann G, Paus T, Spanagel R, Leonardi-Essmann F, Sommer WH, Struve M, Poustka L, Steiner S, Fauth-Bühler M, Vollstädt-Klein S, Schmäl C, IMAGEN consortium . Global genetic variations predict brain response to faces. PLoS Genet. 2014 10(8, e1004523):1-11.
Domi E, Uhrig S, Soverchia L, Spanagel R, Hansson AC, Barbier E, Heilig M, Ciccocioppo R, Ubaldi M. Genetic deletion of neuronal PPARγ enhances the emotional response to acute stress and exacerbates anxiety: An effect reversed by rescue of amygdala PPARγ function. J Neurosci. 2016 36(50):12611-12623. Epub 2016 Nov 3..
Dong L, Bilbao A, Laucht M, Henriksson R, Yakovleva T, Ridinger M, Desrivieres S, Clarke TK, Lourdusamy A, Smolka MN, Cichon S, Blomeyer D, Treutlein J, Perreau-Lenz SP, Witt S, Leonardi-Essmann F, Wodarz N, Zill P, Soyka M, Albrecht U, Rietschel M, Lathrop M, Bakalkin G, Spanagel R, Schumann G. Effects of the Circadian Rhythm Gene Period 1 (Per1) on Psychosocial Stress-Induced Alcohol Drinking. Am J Psychiatry. 2011 168(10):1090-8. Epub 2011 Aug 9.
Drews E, Schneider M, Koch M. Effects of the cannabinoid receptor agonist WIN 55,212-2 on operant behavior and locomotor activity in rats. Pharmacol Biochem Behav. 2005 80(1):145-50.
Dudek M, Abo-Ramadan U, Hermann D, Brown M, Canals S, Sommer WH, Hyytiä P. Brain activation induced by voluntary alcohol and saccharin drinking in rats assessed with manganese-enhanced magnetic resonance imaging. Addict Biol. 2015 20(6):1012-21. Epub 2014 Aug 22.
Dudek M, Canals S, Sommer WH, Hyytiä P. Modulation of nucleus accumbens connectivity by alcohol drinking and naltrexone in alcohol-preferring rats: A manganese-enhanced magnetic resonance imaging study. Eur Neuropsychopharmacol. 2016 26(3):445-55. Epub 2016 Jan 26.
Durrenberger PF, Fernando FS, Kashefi SN, Bonnert TP, Seilhean D, Nait-Oumesmar B, Schmitt A, Gebicke-Haerter PJ, Falkai P, Grünblatt E, Palkovits M, Arzberger T, Kretzschmar H, Dexter DT, Reynolds R. Common mechanisms in neurodegeneration and neuroinflammation: a BrainNet Europe gene expression microarray study. J Neural Transm. 2015 122(7):1055-68. Epub 2014 Aug 13.
Eisenhardt M, Hansson AC, Spanagel R, Bilbao A. Chronic Intermittent Ethanol Exposure in Mice Leads to an Up-Regulation of CRH/CRHR1 Signaling. Alcohol Clin Exp Res. 2015 39(4):752-62.
Eisenhardt M, Leixner S, Luján R, Spanagel R, Bilbao A. Glutamate Receptors within the Mesolimbic Dopamine System Mediate Alcohol Relapse Behavior. J Neurosci. 2015 35(47):15523-38.
Eisenhardt M, Leixner S, Spanagel R, Bilbao A. Quantification of alcohol drinking patterns in mice. Addict Biol. 2015 20(6):1001-11. Epub 2015 Oct 30.
Elagabani MN, Briševac D, Kintscher M, Pohle J, Köhr G, Schmitz D, Kornau HC. Subunit-selective N-Methyl-d-aspartate (NMDA) Receptor Signaling through Brefeldin A-resistant Arf Guanine Nucleotide Exchange Factors BRAG1 and BRAG2 during Synapse Maturation. J Biol Chem. 2016 291(17):9105-18.
Engblom D, Bilbao A, Sanchis-Segura C, Dahan L, Perreau-Lenz SP, Balland B, Parkitna JR, Luján R, Halbout B, Mameli M, Parlato R, Sprengel R, Lüscher C, Schütz G, Spanagel R. Glutamate receptors on dopamine neurons control the persistence of cocaine seeking. Neuron. 2008 59(3):497-508.
Enkel T, Gholizadeh D, von Bohlen und Halbach O, Sanchis-Segura C, Hurlemann R, Spanagel R, Gass P, Vollmayr B. Ambiguous-Cue Interpretation is Biased Under Stress- and Depression-Like States in Rats. Neuropsychopharmacology. 2010 35(4):1008-15. Epub 2009 Dec 30.
Enkel T, Spanagel R, Vollmayr B, Schneider M. Stress Triggers Anhedonia in rats bred for learned helplessness. Behav Brain Res. 2010 209(1):183-6. Epub 2010 Feb 1.
Ewald A, Becker S, Heinrich A, Banaschewski T, Poustka L, Bokde A, Büchel C, Bromberg U, Cattrell A, Conrod P, Desrivieres S, Frouin V, Papadopoulos-Orfanos D, Gallinat J, Garavan H, Heinz A, Walter H, Ittermann B, Gowland P, Paus T, Martinot JL, Martinot MP, Smolka MN, Vetter N, Whelan R, Schumann G, Flor H, Nees F, Diesch E, Gebicke-Haerter PJ, Kiefer F, Vollstädt-Klein S, Rietschel M, Schulze TG, Spanagel R, IMAGEN consortium . The role of the Cannabinoid Receptor 1 in adolescents' processing of facial expressions. Eur J Neurosci. 2016 43(1):98-105. Epub 2015 Nov 3.
Fliegel S, Brand I, Spanagel R, Noori HR. Ethanol-induced alterations of amino acids measured by in vivo microdialysis in rats: a meta-analysis. In Silico Pharmacol. 2013 1:7.
Frank ST, Krumm B, Spanagel R. Cocaine-induced dopamine overflow within the nucleus accumbens measured by in vivo microdialysis: a meta-analysis. Synapse. 2008 62(4):243-52.
Friemel CM, Spanagel R, Schneider M. Reward sensitivity for a palatable food reward peaks during pubertal developmental in rats. Front Behav Neurosci. 2010 4
Friemel CM, Zimmer A, Schneider M. The CB1 Receptor as an Important Mediator of Hedonic Reward Processing. Neuropsychopharmacology. 2014 39(10):2387-96. Epub 2014 Apr 10.
Fritsch V, Da Mota B, Loth E, Varoquaux G, Banaschewski T, Barker GJ, Bokde AL, Brühl R, Butzek B, Conrod P, Flor H, Garavan H, Lemaitre H, Mann K, Nees F, Paus T, Schad DJ, Schumann G, Frouin V, Poline JB, Thirion B, Diesch E, Gebicke-Haerter PJ, Kiefer F, Vollstädt-Klein S, Poustka L, Rietschel M, Schulze TG, Spanagel R, the IMAGEN consortium . Robust regression for large-scale neuroimaging studies. Neuroimage. 2015 111(431-41. Epub Feb 28)
Frölich J, Banaschewski T, Spanagel R, Döpfner M, Lehmkuhl G. [The medical treatment of attention deficit hyperactivity disorder (ADHD) with amphetamines in children and adolescents]. Z Kinder Jugendpsychiatr Psychother. 2012 40(5):287-300.
Füllgrabe MW, Vengeliene V, Spanagel R. Influence of age at drinking onset on the alcohol deprivation effect and stress-induced drinking in female rats. Pharmacol Biochem Behav. 2007 86(2):320-6.
Galinowski A, Miranda R, Lemaitre H, Paillère Martinot ML, Artiges E, Vulser H, Goodman R, Penttilä J, Struve M, Barbot A, Fadai T, Poustka L, Conrod P, Banaschewski T, Barker GJ, Bokde A, Bromberg U, Büchel C, Flor H, Gallinat J, Garavan H, Heinz A, Ittermann B, Kappel V, Lawrence C, Loth E, Mann K, Nees F, Paus T, Pausova Z, Poline JB, Rietschel M, Robbins TW, Smolka M, Schumann G, Martinot JL, Spanagel R, Leonardi-Essmann F, Sommer WH, Vollstädt-Klein S, Steiner S, Fauth-Buehler M, Schmäl C, Schirmbeck F, IMAGEN Consortium . Resilience and corpus callosum microstructure in adolescence. Psychol Med. 2015 45(11):2285-94. Epub 2015 Mar 30.
Gass P, Leonardi-Essmann F, Zueger M, Spanagel R, Gebicke-Haerter PJ. Transcriptional changes in insulin- and lipid metabolism-related genes in the hippocampus of olfactory bulbectomized mice. J Neurosci Res. 2008 86(14):3184-93.
Gebicke-Haerter PJ. Systems biology in molecular psychiatry. Pharmacopsychiatry. 2008 41 Suppl 1:S19-27.
Gebicke-Haerter PJ. Engram formation in psychiatric disorders. Front Neurosci. 2014 8:118.
Gebicke-Haerter PJ, Tretter F. The systems view in addiction research. Addict Biol. 2008 13(3-4):449-54.
Goepfrich AA, Gluch C, Friemel CM, Schneider M. Behavioral differences in three Wistar Han rat lines for emotional reactivity, cognitive processing and ethanol intake. Physiol Behav. 2013 110-111:102-8.
Hadar R, Vengeliene V, Barroeta Hlusicke E, Canals S, Noori HR, Wieske F, Rummel J, Harnack D, Heinz A, Spanagel R, Winter C. Paradoxical augmented relapse in alcohol-dependent rats during deep-brain stimulation in the nucleus accumbens. Transl Psychiatry. 2016 6(6):e840.
Halbout B, Bernardi RE, Hansson AC, Spanagel R. Incubation of Cocaine Seeking following Brief Cocaine Experience in Mice Is Enhanced by mGluR1 Blockade. J Neurosci. 2014 34(5):1781-90.
Halbout B, Perreau-Lenz SP, Dixon CI, Stephens DN, Spanagel R. Per1Brdm1 mice self-administer cocaine and reinstate cocaine-seeking behaviour following extinction. Behav Pharmacol. 2011 22(1):76-80. Epub 2010 Nov 30.
Hampp G, Ripperger JA, Houben T, Schmutz I, Blex C, Perreau-Lenz SP, Brunk I, Spanagel R, Ahnert-Hilger G, Meijer JH, Albrecht U. Regulation of monoamine oxidase A by circadian-clock components implies clock influence on mood. Curr Biol. 2008 18(9):678-83.
Hansson AC, Nixon K, Rimondini R, Damadzic R, Sommer WH, Eskay R, Crews FT, Heilig M. Long-term suppression of forebrain neurogenesis and loss of neuronal progenitor cells following prolonged alcohol dependence in rats. Int J Neuropsychopharmacol. 2010 13(5):583-93. Epub 2010 Mar 25.
Hansson AC, Rimondini R, Heilig M, Mathé AA, Sommer WH. Dissociation of antidepressant-like activity of escitalopram and nortriptyline on behaviour and hippocampal BDNF expression in female rats. J Psychopharmacol. 2011 25(10):1378-87. Epub 2011 Jan 24.
Harasta AE, Power JM, von Jonquieres G, Karl T, Drucker DJ, Housley GD, Schneider M, Klugmann M. Septal Glucagon-Like Peptide 1 Receptor Expression Determines Suppression of Cocaine-Induced Behavior. Neuropsychopharmacology. 2015 40(8):1969-78. Epub 2015 Feb 11.
Heilig M, Sommer WH, Spanagel R. The Need for Treatment Responsive Translational Biomarkers in Alcoholism Research. Curr Top Behav Neurosci. 2016 28:151-71. Epub 2016 May 31.
Heilig M, Thorsell A, Sommer WH, Hansson AC, Ramchandani VA, George DT, Hommer D, Barr CS. Translating the neuroscience of alcoholism into clinical treatments: From blocking the buzz to curing the blues. Neurosci Biobehav Rev. 2010 35(2):334-44. Epub 2009 Nov 24.
Heinrich A, Schumann G, Flor H, Nees F, Banaschewski T, Diesch E, Gebicke-Haerter PJ, Kiefer F, Vollstädt-Klein S, Rietschel M, Schulze TG, Spanagel R, IMAGEN consortium . Identification of Key Items Regarding Personality, Environment, and Life Events to Assess Risk and Resilience Factors for Harmful Alcohol Drinking in Adolescents. Alcohol Alcohol. 2016 118:79-87. Epub 2016 Mar 20.
Helinski S, Spanagel R. Publication trends in addiction research. Addict Biol. 2011 16(4):532-9.
Hermann D, Schneider M. Potential protective effects of cannabidiol on neuroanatomical alterations in cannabis users and psychosis: a critical review. Curr Pharm Des. 2012 18(32):4897-905.
Hermann D, Weber-Fahr W, Sartorius A, Hoerst M, Frischknecht U, Tunc-Skarka N, Perreau-Lenz SP, Hansson AC, Krumm B, Kiefer F, Spanagel R, Mann K, Ende G, Sommer WH. Translational Magnetic Resonance Spectroscopy Reveals Excessive Central Glutamate Levels During Alcohol Withdrawal in Humans and Rats. Biol Psychiatry. 2012 71(11):1015-21. Epub 2011 Sep 10.
Herrera-Marschitz M, Neira-Pena T, Rojas-Mancilla E, Espina-Marchant P, Esmar D, Perez R, Muñoz V, Gutierrez-Hernandez M, Rivera B, Simola N, Bustamante D, Morales P, Gebicke-Haerter PJ. Perinatal asphyxia: CNS development and deficits with delayed onset. Front Neurosci. 2014 8:47.
Herwerth M, Jensen V, Novak M, Konopka W, Hvalby O, Köhr G. D4 dopamine receptors modulate NR2B NMDA receptors and LTP in stratum oriens of hippocampal CA1. Cereb Cortex. 2012 22(8):1786-98.
Hibar DP, Stein JL, Rentería ME, Arias-Vásquez A, Desrivieres S, Jahanshad N, Toro R, Wittfeld K, Abramovic L, Andersson M, Aribisala BS, Armstrong NJ, Bernard M, Bohlken MM, Boks MP, Bralten J, Brown AA, Mallar Chakravarty M, Chen Q, Ching CR, Cuellar-Partida G, den Braber A, Giddaluru S, Goldman AL, Grimm O, Guadalupe T, Hass J, Woldehawariat G, Holmes AJ, Hoogman M, Janowitz D, Jia T, Kim S, Klein M, Kraemer B, Lee PH, Olde Loohuis LM, Luciano M, Macare C, Mather KA, Mattheisen M, Milaneschi Y, Nho K, Papmeyer M, Ramasamy A, Risacher SL, Roiz-Santiañez R, Rose EJ, Salami A, Sämann PG, Schmaal L, Schork AJ, Shin J, Strike LT, Teumer A, van Donkelaar MM, van Eijk KR, Walters RK, Westlye LT, Whelan CD, Winkler AM, Zwiers MP, Alhusaini S, Athanasiu L, Ehrlich S, Hakobjan MM, Hartberg CB, Haukvik UK, Heister AJ, Hoehn D, Kasperaviciute D, Liewald DC, Lopez LM, Makkinje RR, Matarin M, Naber MA, Reese McKay D, Needham M, Nugent AC, Pütz B, Royle NA, Shen L, Sprooten E, Trabzuni D, van der Marel SS, van Hulzen KJ, Walton E, Wolf C, Almasy L, Ames D, Arepalli S, Assareh AA, Bastin ME, Brodaty H, Bulayeva KB, Carless MA, Cichon S, Corvin A, Curran JE, Czisch M, de Zubicaray GI, Dillman A, Duggirala R, Dyer TD, Erk S, Fedko IO, Ferrucci L, Foroud TM, Fox PT, Fukunaga M, Raphael Gibbs J, Göring HH, Green RC, Guelfi S, Hansell NK, Hartman CA, Hegenscheid K, Heinz A, Hernandez DG, Heslenfeld DJ, Hoekstra PJ, Holsboer F, Homuth G, Hottenga JJ, Ikeda M, Jack CR, Jenkinson M, Johnson R, Kanai R, Keil M, Kent JW, Kochunov P, Kwok JB, Lawrie SM, Liu X, Longo DL, McMahon KL, Meisenzahl E, Melle I, Mohnke S, Montgomery GW, Mostert JC, Mühleisen TW, Nalls MA, Nichols TE, Nilsson LG, Nöthen MM, Ohi K, Olvera RL, Perez-Iglesias R, Bruce Pike G, Potkin SG, Reinvang I, Reppermund S, Rietschel M, Romanczuk-Seiferth N, Rosen GD, Rujescu D, Schnell K, Schofield PR, Smith C, Steen VM, Sussmann JE, Thalamuthu A, Toga AW, Traynor BJ, Troncoso J, Turner JA, Valdés Hernández MC, van 't Ent D, van der Brug M, van der Wee NJ, van Tol MJ, Veltman DJ, Wassink TH, Westman E, Zielke RH, Zonderman AB, Ashbrook DG, Hager R, Lu L, McMahon FJ, Morris DW, Williams RW, Brunner HG, Buckner RL, Buitelaar JK, Cahn W, Calhoun VD, Cavalleri GL, Crespo-Facorro B, Dale AM, Davies GE, Delanty N, Depondt C, Djurovic S, Drevets WC, Espeseth T, Gollub RL, Ho BC, Hoffmann W, Hosten N, Kahn RS, Le Hellard S, Meyer-Lindenberg A, Müller-Myhsok B, Nauck M, Nyberg L, Pandolfo M, Penninx BW, Roffman JL, Sisodiya SM, Smoller JW, van Bokhoven H, Van Haren NE, Völzke H, Walter H, Weiner MW, Wen W, White T, Agartz I, Andreassen OA, Blangero J, Boomsma DI, Brouwer RM, Cannon DM, Cookson MR, de Geus EJ, Deary IJ, Donohoe G, Fernández G, Fisher SE, Francks C, Glahn DC, Grabe HJ, Gruber O, Hardy J, Hashimoto R, Hulshoff Pol HE, Jönsson EG, Kloszewska I, Lovestone S, Mattay VS, Mecocci P, McDonald C, McIntosh AM, Ophoff RA, Paus T, Pausova Z, Ryten M, Sachdev PS, Saykin AJ, Simmons A, Singleton A, Soininen H, Wardlaw JM, Weale ME, Weinberger DR, Adams HH, Launer LJ, Seiler S, Schmidt R, Chauhan G, Satizabal CL, Becker JT, Yanek L, van der Lee SJ, Ebling M, Fischl B, Longstreth WT, Greve D, Schmidt H, Nyquist P, Vinke LN, van Duijn CM, Xue L, Mazoyer B, Bis JC, Gudnason V, Seshadri S, Arfan Ikram M, The Alzheimer’s Disease Neuroimaging Initiative , The CHARGE Consortium , EPIGEN , SYS , Martin NG, Wright MJ, Schumann G, Franke B, Thompson PM, Medland SE, Banaschewski T, Diesch E, Flor H, Gebicke-Haerter PJ, Kiefer F, Vollstädt-Klein S, Schulze TG, Spanagel R, IMAGEN . Common genetic variants influence human subcortical brain structures. Nature. 2015 520(7546):224-9. Epub 2015 Jan 21.
Hirth N, Meinhardt MW, Noori HR, Salgado H, Torres-Ramirez O, Uhrig S, Broccoli L, Vengeliene V, Roßmanith M, Perreau-Lenz SP, Köhr G, Sommer WH, Spanagel R, Hansson AC. Convergent evidence from alcohol-dependent humans and rats for a hyperdopaminergic state in protracted abstinence. Proc Natl Acad Sci U S A. 2016 113(11):3024-9. Epub Feb 22.
Holmes A, Spanagel R, Krystal JH. Glutamatergic targets for new alcohol medications. Psychopharmacology (Berl). 2013 229(3):539-54. Epub 2013 Sep 1.
Huang H, Tan BZ, Shen Y, Tao J, Jiang F, Sung YY, Ng CK, Raida M, Köhr G, Higuchi M, Fatemi-Shariatpanahi H, Harden B, Yue DT, Soong TW. RNA editing of the IQ domain in Ca(v)1.3 channels modulates their Ca²⁺-dependent inactivation. Neuron. 2012 73(2):304-16.
Inta D, Lima-Ojeda JM, Dormann C, Köhr G, Sprengel R, Gass P. Combined subunit-specific and unspecific inhibition of NMDA receptors triggers distinct cortical c-fos expression patterns. Synapse. 2012 66(8):752-4. Epub 2012 May 15..
Inta D, Vogt MA, Elkin H, Weber T, Lima-Ojeda JM, Schneider M, Luoni A, Riva MA, Gertz K, Hellmann-Regen J, Kronenberg G, Meyer-Lindenberg A, Sprengel R, Gass P. Phenotype of mice with inducible ablation of GluA1 AMPA receptors during late adolescence: relevance for mental disorders. Hippocampus. 2014 24(4):424-35. Epub 2013 Dec 12.
Inta D, Vogt MA, Lima-Ojeda JM, Pfeiffer N, Schneider M, Gass P. Lack of long-term behavioral alterations after early postnatal treatment with tropisetron: Implications for developmental psychobiology. Pharmacol Biochem Behav. 2011 99(1):35-41. Epub 2011 Mar 31.
Inta D, Vogt MA, Perreau-Lenz SP, Schneider M, Pfeiffer N, Wojcik SM, Spanagel R, Gass P. Sensorimotor gating, working and social memory deficits in mice with reduced expression of the vesicular glutamate transporter VGLUT1. Behav Brain Res. 2012 228(2):328-32. Epub 2011 Dec 16.
Inta D, Vogt MA, Pfeiffer N, Köhr G, Gass P. Dichotomy in the anxiolytic versus antidepressant effect of C-terminal truncation of the GluN2A subunit of NMDA receptors. Behav Brain Res. 2013 247:227-31.
Jia T, Macare C, Desrivieres S, Gonzalez DA, Tao C, Ji X, Ruggeri B, Nees F, Banaschewski T, Barker GJ, Bokde AL, Bromberg U, Büchel C, Conrod PJ, Dove R, Frouin V, Gallinat J, Garavan H, Gowland PA, Heinz A, Ittermann B, Lathrop M, Lemaitre H, Martinot JL, Paus T, Pausova Z, Poline JB, Rietschel M, Robbins T, Smolka MN, Müller CP, Feng J, Rothenfluh A, Flor H, Schumann G, Schulze TG, Spanagel R, Diesch E, Gebicke-Haerter PJ, Kiefer F, Vollstädt-Klein S, IMAGEN Consortium . Neural basis of reward anticipation and its genetic determinants. Proc Natl Acad Sci U S A. 2016 113(14):3879-84. Epub 2016 Mar 21.
Jorde A, Bach P, Witt SH, Becker K, Reinhard I, Vollstädt-Klein S, Kirsch M, Hermann D, Charlet K, Beck A, Wimmer L, Frank J, Treutlein J, Spanagel R, Mann K, Walter H, Heinz A, Rietschel M, Kiefer F. Genetic Variation in the Atrial Natriuretic Peptide Transcription Factor GATA4 Modulates Amygdala Responsiveness in Alcohol Dependence. Biol Psychiatry. 2014 75(10):790-7. Epub 2013 Nov 4.
Juraeva D, Treutlein J, Scholz H, Frank J, Degenhardt F, Cichon S, Ridinger M, Mattheisen M, Witt SH, Lang M, Sommer WH, Hoffmann P, Herms S, Wodarz N, Soyka M, Zill P, Maier W, Jünger E, Gaebel W, Dahmen N, Scherbaum N, Schmäl C, Steffens M, Lucae S, Ising M, Smolka MN, Zimmermann US, Müller-Myhsok B, Nöthen MM, Mann K, Kiefer F, Spanagel R, Brors B, Rietschel M. XRCC5 as a Risk Gene for Alcohol Dependence: Evidence from a Genome-Wide Gene-Set Based Analysis and Follow-up Studies in Drosophila and Humans. Neuropsychopharmacology. 2015 40(2):361-371. Epub 2014 Jul 18.
Jurk S, Kuitunen-Paul S, Kroemer NB, Artiges E, Banaschewski T, Bokde AL, Büchel C, Conrod P, Fauth-Bühler M, Flor H, Frouin V, Gallinat J, Garavan H, Heinz A, Mann KF, Nees F, Paus T, Pausova Z, Poustka L, Rietschel M, Schumann G, Struve M, Smolka MN, Diesch E, Gebicke-Haerter PJ, Kiefer F, Vollstädt-Klein S, Schulze TG, Spanagel R, IMAGEN consortium . Personality and Substance Use: Psychometric Evaluation and Validation of the Substance Use Risk Profile Scale (SURPS) in English, Irish, French, and German Adolescents. Alcohol Clin Exp Res. 2015 39(11):2234-48. Epub 2015 Oct 14.
Kalsbeek A, Scheer FA, Perreau-Lenz SP, La Fleur SE, Yi CX, Fliers E, Buijs RM. Circadian disruption and SCN control of energy metabolism. FEBS Lett. 2011 585(10):1412-26.
Karlsson RM, Adermark L, Molander A, Perreau-Lenz SP, Singley E, Solomon M, Holmes A, Tanaka K, Lovinger DM, Spanagel R, Heilig M. Reduced alcohol intake and reward associated with impaired endocannabinoid signaling in mice with a deletion of the glutamate transporter GLAST. Neuropharmacology. 2012 63(2):181-9. Epub 2012 Feb 9..
Karrenbauer BD, Ho YJ, Ludwig V, Löhn J, Spanagel R, Schwarting RK, Pawlak CR. Time-dependent effects of striatal interleukin-2 on open field behaviour in rats. J Neuroimmunol. 2009 208(1-2):10-8.
Karrenbauer BD, Müller CP, Ho YJ, Spanagel R, Huston JP, Schwarting RK, Pawlak CR. Time-dependent in-vivo effects of interleukin-2 on neurotransmitters in various cortices: relationships with depressive-related and anxiety-like behaviour. J Neuroimmunol. 2011 237(1-2):23-32.
Kiefer F, Kirsch M, Bach P, Hoffmann S, Reinhard I, Jorde A, von der Goltz C, Spanagel R, Mann K, Loeber S, Vollstädt-Klein S. Effects of D-cycloserine on extinction of mesolimbic cue reactivity in alcoholism: a randomized placebo-controlled trial. Psychopharmacology (Berl). 2015 232(13):2353-62. Epub 2015 Feb 21.
Kiefer F, Spanagel R. Measuring alcohol consumption in man--it is time for a change. Addiction. 2006 101(8):1215-6; author reply 1216-7.
Kiefer F, Witt SH, Frank J, Richter A, Treutlein J, Leménager T, Nöthen MM, Cichon S, Batra A, Berner M, Wodarz N, Zimmermann US, Spanagel R, Wiedemann K, Smolka MN, Heinz A, Rietschel M, Mann K. Involvement of the atrial natriuretic peptide transcription factor GATA4 in alcohol dependence, relapse risk and treatment response to acamprosate. Pharmacogenomics J. 2011 11(5):368-74.
Klein J, Hadar R, Götz T, Männer A, Eberhardt C, Baldassarri J, Schmidt TT, Kupsch A, Heinz A, Morgenstern R, Schneider M, Weiner I, Winter C. Mapping brain regions in which deep brain stimulation affects schizophrenia-like behavior in two rat models of schizophrenia. Brain Stimul. 2013 6(4):490-9.
Klugmann M, Goepfrich A, Friemel CM, Schneider M. AAV-Mediated Overexpression of the CB1 Receptor in the mPFC of Adult Rats Alters Cognitive Flexibility, Social Behavior, and Emotional Reactivity. Front Behav Neurosci. 2011 5:37.
Klugmann M, Klippenstein V, Leweke FM, Spanagel R, Schneider M. Cannabinoid exposure in pubertal rats increases spontaneous ethanol consumption and NMDA receptor associated protein levels. Int J Neuropsychopharmacol. 2011 14(4):505-17. Epub 2011 Jan 7.
Konopka W, Kiryk A, Novak M, Herwerth M, Parkitna JR, Wawrzyniak M, Kowarsch A, Michaluk P, Dzwonek J, Arnsperger T, Wilczynski G, Merkenschlager M, Theis FJ, Köhr G, Kaczmarek L, Schütz G. MicroRNA loss enhances learning and memory in mice. J Neurosci. 2010 30(44):14835-42.
Kuhrt H, Gryga M, Wolburg H, Joffe B, Grosche J, Reichenbach A, Noori HR. Postnatal mammalian retinal development: quantitative data and general rules. Prog Retin Eye Res. 2012 31(6):605-21.
Kuner R, Köhr G, Grünewald S, Eisenhardt G, Bach A, Kornau HC. Role of heteromer formation in GABAB receptor function. Science. 1999 283(5398):74-7.
Köhr G, Eckardt S, Lüddens H, Monyer H, Seeburg PH. NMDA receptor channels: subunit-specific potentiation by reducing agents. Neuron. 1994 12(5):1031-40.
Kühn S, Witt C, Banaschewski T, Barbot A, Barker GJ, Büchel C, Conrod PJ, Flor H, Garavan H, Ittermann B, Mann K, Martinot JL, Paus T, Rietschel M, Smolka MN, Ströhle A, Brühl R, Schumann G, Heinz A, Gallinat J, Diesch E, Gebicke-Haerter PJ, Kiefer F, Vollstädt-Klein S, Schulze TG, Spanagel R, IMAGEN Consortium . From mother to child: orbitofrontal cortex gyrification and changes of drinking behaviour during adolescence. Addict Biol. 2016 21(3):700-8. epub 2015 Apr 24.
Lancaster TM, Linden DE, Tansey KE, Banaschewski T, Bokde AL, Bromberg U, Büchel C, Cattrell A, Conrod PJ, Flor H, Frouin V, Gallinat J, Garavan H, Gowland P, Heinz A, Ittermann B, Martinot JL, Martinot MP, Artiges E, Lemaitre H, Nees F, Orfanos DP, Paus T, Poustka L, Smolka MN, Vetter NC, Jurk S, Mennigen E, Walter H, Whelan R, Schumann G, Rietschel M, Spanagel R, Fauth-Bühler M, Millenet S, Grimmer Y, IMAGEN Consortium . Polygenic Risk of Psychosis and Ventral Striatal Activation During Reward Processing in Healthy Adolescents. JAMA Psychiatry. 2016 73(8):852-61. Epub 2016 Jul 6.
Lee YT, Wang WF, Cheng CW, Wu SL, Pawlak CR, Ho YJ. Effects of escapable and inescapable stressors on behavior and interleukin-2 in the brain. Neuroreport. 2008 19(12):1243-7.
Leweke FM, Giuffrida A, Koethe D, Schreiber D, Nolden BM, Kranaster L, Neatby MA, Schneider M, Gerth CW, Hellmich M, Klosterkötter J, Piomelli D. Anandamide levels in cerebrospinal fluid of first-episode schizophrenic patients: impact of cannabis use. Schizophr Res. 2007 94(1-3):29-36.
Leweke FM, Schneider M. Chronic pubertal cannabinoid treatment as a behavioural model for aspects of schizophrenia: effects of the atypical antipsychotic quetiapine. Int J Neuropsychopharmacol. 2011 14(1):43-51. Epub 2010 Aug 3.
Li SB, Du D, Hasan MT, Köhr G. D4 Receptor Activation Differentially Modulates Hippocampal Basal and Apical Dendritic Synapses in Freely Moving Mice. Cereb Cortex. 2016 26(2):647-55. Epub 2014 Sep 30.
Lima-Ojeda JM, Vogt MA, Pfeiffer N, Dormann C, Köhr G, Sprengel R, Gass P, Inta D. Pharmacological blockade of GluN2B-containing NMDA receptors induces antidepressant-like effects lacking psychotomimetic action and neurotoxicity in the perinatal and adult rodent brain. Prog Neuropsychopharmacol Biol Psychiatry. 2013 45:28-33. Epub 2013 Apr 30.
Lima-Ojeda JM, Vogt MA, Richter SH, Dormann C, Schneider M, Gass P, Inta D. Lack of protracted behavioral abnormalities following intermittent or continuous chronic mild hypoxia in perinatal C57BL/6 mice. Neurosci Lett. 2014 577:77-82. Epub 2014 Jun 14.
Lindell SG, Schwandt ML, Sun H, Sparenborg JD, Björk K, Kasckow JW, Sommer WH, Goldman D, Higley JD, Suomi SJ, Heilig M, Barr CS. Functional NPY variation as a factor in stress resilience and alcohol consumption in rhesus macaques. Arch Gen Psychiatry. 2010 67(4):423-31.
Litscher D, Wang X, Schneider M, Friemel CM, Litscher G. Inhibitory Effects of 658 nm Laser Irradiation on Skin Temperature in Anesthetized Rats: Preliminary Results from a Controlled Study. Int J Photoenergy. 2014 (Article ID 275765):1-8.
Ludascher P, Schmahl C, Feldmann RE, Kleindienst N, Schneider M, Bohus M. No evidence for differential dose effects of hydrocortisone on intrusive memories in female patients with complex post-traumatic stress disorder - a randomized, double-blind, placebo-controlled, crossover study. J Psychopharmacol. 2015 29(10):1077-84. Epub 2015 Jul 6.
Mahmoud S, Thorsell A, Sommer WH, Heilig M, Holgate JK, Bartlett SE, Ruiz-Velasco V. Pharmacological Consequence of the A118G ? Opioid Receptor Polymorphism on Morphine- and Fentanyl-mediated Modulation of Ca2+ Channels in Humanized Mouse Sensory Neurons. Anesthesiology. 2011 115(5):1054-1062.
Mameli M, Halbout B, Creton C, Engblom D, Parkitna JR, Spanagel R, Lüscher C. Cocaine-evoked synaptic plasticity: persistence in the VTA triggers adaptations in the NAc. Nat Neurosci. 2009 12(8):1036-41. Epub 2009 Jul 13.
Mann K, Kiefer F, Spanagel R, Littleton J. Acamprosate: recent findings and future research directions. Alcohol Clin Exp Res. 2008 32(7):1105-10.
Mareckova K, Perrin JS, Nawaz Khan I, Lawrence C, Dickie E, McQuiggan DA, Paus T, Spanagel R, Leonardi-Essmann F, Sommer W, Flor H, Nees F, Banaschewski T, Poustka L, Steiner S, Mann K, Fauth-Bühler M, Vollstädt-Klein S, Rietschel M, Schmael C, IMAGEN Consortium . Hormonal contraceptives, menstrual cycle and brain response to faces. Soc Cogn Affect Neurosci. 2014 9(2):191-200.
Matthäus F, Smith VA, Fogtman A, Sommer WH, Leonardi-Essmann F, Lourdusamy A, Reimers MA, Spanagel R, Gebicke-Haerter PJ. Interactive molecular networks obtained by computer-aided conversion of microarray data from brains of alcohol-drinking rats. Pharmacopsychiatry. 2009 42 Suppl 1:S118-28.
Meinhardt MW, Hansson AC, Perreau-Lenz SP, Bauder-Wenz C, Stählin O, Heilig M, Harper C, Drescher KU, Spanagel R, Sommer WH. Rescue of Infralimbic mGluR2 Deficit Restores Control Over Drug-Seeking Behavior in Alcohol Dependence. J Neurosci. 2013 33(7):2794-806.
Meinhardt MW, Sommer WH. Postdependent state in rats as a model for medication development in alcoholism. Addict Biol. 2015 20(1):1-21. Epub 2014 Nov 17.
Meinhardt MW, Sévin DC, Klee ML, Dieter S, Sauer U, Sommer WH. The Neurometabolic Fingerprint of Excessive Alcohol Drinking. Neuropsychopharmacology. 2015 40:1259-68. Epub 2014 Nov 24.
Molander A, Vengeliene V, Heilig M, Wurst W, Deussing JM, Spanagel R. Brain-Specific Inactivation of the Crhr1 Gene Inhibits Post-Dependent and Stress-Induced Alcohol Intake, but Does Not Affect Relapse-Like Drinking. Neuropsychopharmacology. 2012 37(4):1047-56. Epub 2011 Nov 23..
Morales P, Simola N, Bustamante D, Lisboa F, Fiedler J, Gebicke-Haerter PJ, Morelli M, Tasker RA, Herrera-Marschitz M. Nicotinamide prevents the long-term effects of perinatal asphyxia on apoptosis, non-spatial working memory and anxiety in rats. Exp Brain Res. 2010 202(1):1-14.
Mosienko V, Matthes S, Hirth N, Beis D, Flinders M, Bader M, Hansson AC, Alenina N. Adaptive changes in serotonin metabolism preserve normal behavior in mice with reduced TPH2 activity. Neuropharmacology. 2014 85:73-80. Epub 2014 May 23.
Mutschler J, Bilbao A, von der Goltz C, Demiralay C, Jahn H, Wiedemann K, Spanagel R, Kiefer F. Augmented Stress-Induced Alcohol Drinking and Withdrawal in Mice Lacking Functional Natriuretic Peptide-A Receptors. Alcohol Alcohol. 2010 45(1):13-6. Epub 2009 Oct 13.
Müller KU, Gan G, Banaschewski T, Barker GJ, Bokde AL, Büchel C, Conrod P, Fauth-Bühler M, Flor H, Gallinat J, Garavan H, Gowland P, Heinz A, Ittermann B, Lawrence C, Loth E, Mann K, Martinot JL, Nees F, Paus T, Pausova Z, Rietschel M, Ströhle A, Struve M, Schumann G, Smolka MN, IMAGEN Consortium , Vollstädt-Klein S, Spanagel R, Millenet S, Grimmer Y, The IMAGEN Consortium . No differences in ventral striatum responsivity between adolescents with a positive family history of alcoholism and controls. Addict Biol. 2015 20(3):534-45. Epub 2015 Jun 5.
Nees F, Tzschoppe J, Patrick CJ, Vollstädt-Klein S, Steiner S, Poustka L, Banaschewski T, Barker GJ, Büchel C, Conrod PJ, Garavan H, Heinz A, Gallinat J, Lathrop M, Mann K, Artiges E, Paus T, Poline JB, Robbins TW, Rietschel M, Smolka MN, Spanagel R, Struve M, Loth E, Schumann G, Flor H. Determinants of Early Alcohol Use In Healthy Adolescents: The Differential Contribution of Neuroimaging and Psychological Factors. Neuropsychopharmacology. 2012 37(4):E986-95. Epub 2011 Nov 23..
Neznanova O, Björk K, Rimondini R, Hansson AC, Hyytiä P, Heilig M, Sommer W. Acute ethanol challenge inhibits glycogen synthase kinase-3beta in the rat prefrontal cortex. Int J Neuropsychopharmacol. 2009 12(2):275-80.
Ng B, Poline JB, Thirion B, Greicius M, Banaschewski T, Diesch E, Flor H, Gebicke-Haerter PJ, Kiefer F, Vollstädt-Klein S, Poustka L, Rietschel M, Schulze TG, Spanagel R, IMAGEN Consortium . Bootstrapped Permutation Test for Multiresponse Inference on Brain Behavior Associations. Inf Process Med Imaging. 2015 24:113-24.
Noori HR. The impact of the glial spatial buffering on the K(+) Nernst potential. Cogn Neurodyn. 2011 5(3):285-91.
Noori HR. Substantial changes in synaptic firing frequencies induced by glial ATP hysteresis. Biosystems. 2011 105(3):238-42.
Noori HR. The effects of the acute administration of low-dosage ethanol on the phasic neurochemical oscillations of the basal ganglia. Math Med Biol. 2012 29(3):231-44.
Noori HR. Multi-scale modeling of complex neuronal networks: a view towards striatal pattern formations. J Biol Phys. 2012 38(4):597-606.
Noori HR. Multi-scale modeling of complex neuronal networks: a view towards striatal cholinergic pattern formations. J Biol Phys. 2012 38(4):597-606.
Noori HR, Cosa Linan A, Spanagel R. Largely overlapping neuronal substrates of reactivity to drug, gambling, food and sexual cues: A comprehensive meta-analysis. Eur Neuropsychopharmacol. 2016 26(9):1419-30. Epub 2016 Jul 7.
Noori HR, Fliegel S, Brand I, Spanagel R. The impact of acetylcholinesterase inhibitors on the extracellular acetylcholine concentrations in the adult rat brain: A meta-analysis. Synapse. 2012 66(10):893-901.
Noori HR, Fornal CA. The appropriateness of unbiased optical fractionators to assess cell proliferation in the adult hippocampus. Front Neurosci. 2011 5:140.
Noori HR, Helinski S, Spanagel R. Cluster and meta-analyses on factors influencing stress-induced alcohol drinking and relapse in rodents. Addict Biol. 2014 19(2):225-32.
Noori HR, Jäger W. Neurochemical oscillations in the basal ganglia. Bull Math Biol. 2010 72(1):133-47.
Noori HR, Mücksch C, Urbassek HM. A Structural Feature of the Non-Peptide Ligand Interactions with Mice Mu-Opioid Receptors. Curr Comput Aided Drug Des. 2014 10(4):354-60. Epub 2014 Oct 30.
Noori HR, Spanagel R. Quantum modeling of common sense. Behav Brain Sci. 2013 36(3):302.
Noori HR, Spanagel R. In silico pharmacology: drug design and discovery's gate to the future. In Silico Pharmacol. 2013 1:1.
Noori HR, Spanagel R. New regulations for animal research - a chance to shine for in silico approaches. In Silico Pharmacol. 2015 3:1.
Noori HR, Spanagel R, Hansson AC. Neurocircuitry for modeling drug effects. Addict Biol. 2012 17(5):827-64.
Novak M, Halbout B, O'Connor EC, Rodriguez Parkitna J, Su T, Chai M, Crombag HS, Bilbao A, Spanagel R, Stephens DN, Schütz G, Engblom D. Incentive Learning Underlying Cocaine-Seeking Requires mGluR5 Receptors Located on Dopamine D1 Receptor-Expressing Neurons. J Neurosci. 2010 30(36):11973-82.
Nymberg C, Banaschewski T, Bokde AL, Büchel C, Conrod P, Flor H, Frouin V, Garavan H, Gowland P, Heinz A, Ittermann B, Mann K, Martinot JL, Nees F, Paus T, Pausova Z, Rietschel M, Robbins TW, Smolka MN, Ströhle A, Schumann G, Klingberg T, Spanagel R, Leonardi-Essmann F, Sommer WH, Vollstädt-Klein S, Poustka L, Steiner S, Fauth-Bühler M, Schmäl C, Schirmbeck F, IMAGEN consortium . DRD2/ANKK1 Polymorphism Modulates the Effect of Ventral Striatal Activation on Working Memory Performance. Neuropsychopharmacology. 2014 39(10):2357-65. Epub 2014 Apr 9.
O'Leary-Barrett M, Pihl RO, Artiges E, Banaschewski T, Bokde AL, Büchel C, Flor H, Frouin V, Garavan H, Heinz A, Ittermann B, Mann K, Paillere-Martinot ML, Nees F, Paus T, Pausova Z, Poustka L, Rietschel M, Robbins TW, Smolka MN, Ströhle A, Schumann G, Conrod PJ, Schulze TG, Spanagel R, Diesch E, Gebicke-Haerter PJ, Kiefer F, Vollstädt-Klein S, IMAGEN Consortium . Personality, Attentional Biases towards Emotional Faces and Symptoms of Mental Disorders in an Adolescent Sample. PLoS ONE. 2015 10(6):e0128271.
Oettl LL, Ravi N, Schneider M, Scheller MF, Schneider P, Mitre M, da Silva Gouveia M, Froemke RC, Chao MV, Young WS, Meyer-Lindenberg A, Grinevich V, Shusterman R, Kelsch W. Oxytocin Enhances Social Recognition by Modulating Cortical Control of Early Olfactory Processing. Neuron. 2016 90(3):609-21. Epub 2016 Apr 20.
Ojelade SA, Jia T, Rodan AR, Chenyang T, Kadrmas JL, Cattrell A, Ruggeri B, Charoen P, Lemaitre H, Banaschewski T, Büchel C, Bokde AL, Carvalho F, Conrod PJ, Flor H, Frouin V, Gallinat J, Garavan H, Gowland PA, Heinz A, Ittermann B, Lathrop M, Lubbe S, Martinot JL, Paus T, Smolka MN, Spanagel R, O'Reilly PF, Laitinen J, Veijola JM, Feng J, Desrivieres S, Jarvelin MR, Diesch E, Gebicke-Haerter PJ, Kiefer F, Vollstädt-Klein S, Poustka L, Rietschel M, Schulze TG, Schumann G, Nees F, Rothenfluh A, Grimmer Y, Fauth-Bühler M, Millenet S, IMAGEN Consortium . Rsu1 regulates ethanol consumption in Drosophila and humans. Proc Natl Acad Sci U S A. 2015 112(30):E4085-93. Epub 2015 Jul 13.
Ortuño-Sierra J, Fonseca-Pedrero E, Aritio-Solana R, Velasco AM, de Luis EC, Schumann G, Cattrell A, Flor H, Nees F, Banaschewski T, Bokde A, Whelan R, Buechel C, Bromberg U, Conrod P, Frouin V, Papadopoulos D, Gallinat J, Garavan H, Heinz A, Walter H, Struve M, Gowland P, Paus T, Poustka L, Martinot JL, Paillere-Martinot ML, Vetter NC, Smolka MN, Lawrence C, Diesch E, Gebicke-Haerter PJ, Kiefer F, Vollstädt-Klein S, Rietschel M, Schulze TG, Spanagel R, IMAGEN consortium . New evidence of factor structure and measurement invariance of the SDQ across five European nations. Eur Child Adolesc Psychiatry. 2015 24(12):1523-1534. Epub 2015 Jun 3.
Paillère Martinot ML, Lemaitre H, Artiges E, Miranda R, Goodman R, Penttilä J, Struve M, Fadai T, Kappel V, Poustka L, Conrod P, Banaschewski T, Barbot A, Barker GJ, Büchel C, Flor H, Gallinat J, Garavan H, Heinz A, Ittermann B, Lawrence C, Loth E, Mann K, Paus T, Pausova Z, Rietschel M, Robbins TW, Smolka MN, Schumann G, Martinot JL, Leonardi-Essmann F, Spanagel R, Sommer WH, Vollstädt-Klein S, Nees F, Steiner S, Fauth-Bühler M, Schmäl C, Schirmbeck F, IMAGEN consortium . White-matter microstructure and gray-matter volumes in adolescents with subthreshold bipolar symptoms. Mol Psychiatry. 2014 19(4):462-70.
Papale A, Morella IM, Indrigo MT, Eugene Bernardi R, Marrone L, Marchisella F, Brancale A, Spanagel R, Brambilla R, Fasano S. Impairment of cocaine-mediated behaviours in mice by clinically relevant Ras-ERK inhibitors. Elife. 2016 5
Pawlak CR, Ho YJ, Schwarting RK. Animal models of human psychopathology based on individual differences in novelty-seeking and anxiety. Neurosci Biobehav Rev. 2008 32(8):1544-68.
Pawlak CR, Sanchis-Segura C, Soewarto D, Wagner S, Hrabé de Angelis M, Spanagel R. A phenotype-driven ENU mutagenesis screen for the identification of dominant mutations involved in alcohol consumption. Mamm Genome. 2008 19(2):77-84.
Perez de la Mora M, Gallegos-Cari A, Crespo-Ramirez M, Marcellino D, Hansson AC, Fuxe K. Distribution of dopamine D(2)-like receptors in the rat amygdala and their role in the modulation of unconditioned fear and anxiety. Neuroscience. 2012 201:252-66.
Perreau-Lenz SP, Sanchis-Segura C, Leonardi-Essmann F, Schneider M, Spanagel R. Development of morphine-induced tolerance and withdrawal: Involvement of the clock gene mPer2. Eur Neuropsychopharmacol. 2010 20(7):509-17. Epub 2010 Apr 29.
Perreau-Lenz SP, Spanagel R. The effects of drugs of abuse on clock genes. Drug News Perspect. 2008 21(4):211-7.
Perreau-Lenz SP, Spanagel R. Clock genes × stress × reward interactions in alcohol and substance use disorders. Alcohol. 2015 49(4):351-7. Epub 2015 Apr 24.
Perreau-Lenz SP, Vengeliene V, Noori HR, Merlo-Pich EV, Corsi MA, Corti C, Spanagel R. Inhibition of the Casein-Kinase-1-Epsilon/Delta Prevents Relapse-Like Alcohol Drinking. Neuropsychopharmacology. 2012 37(9):2121-31. Epub 2012 May 2.
Perreau-Lenz SP, Zghoul T, Spanagel R. Clock genes running amok. Clock genes and their role in drug addiction and depression. EMBO Rep. 2007 8 :S20-3.
Perreau-Lenz SP, Zghoul T, de Fonseca FR, Spanagel R, Bilbao A. Circadian regulation of central ethanol sensitivity by the mPer2 gene. Addict Biol. 2009 14(3):253-9.
Peselmann N, Schmitt A, Gebicke-Haerter PJ, Zink M. Aripiprazole differentially regulates the expression of Gad67 and ?-aminobutyric acid transporters in rat brain. Eur Arch Psychiatry Clin Neurosci. 2013 263(4):285-97. Epub 2012 Sep 12.
Pfarr S, Meinhardt MW, Klee ML, Hansson AC, Vengeliene V, Schönig K, Bartsch D, Hope BT, Spanagel R, Sommer WH. Losing Control: Excessive Alcohol Seeking after Selective Inactivation of Cue-Responsive Neurons in the Infralimbic Cortex. J Neurosci. 2015 35(30):10750-61.
Pohle J, Bischofberger J. Supralinear dendritic Ca(2+) signalling in young developing CA1 pyramidal cells. J Physiol. 2014 592(Pt 22):4931-49.
Punnakkal P, Jendritza P, Köhr G. Influence of the intracellular GluN2 C-terminal domain on NMDA receptor function. Neuropharmacology. 2012 62(5-6):1985-92.
Qin WJ, Wang YT, Li PM, Wang XX, Li JX, Noori HR, Bernardi RE, Liang JH, Zhang XL. Context- and time-dependent neurobiological and behavioral sensitization induced by a single morphine exposure in mice. Psychopharmacology (Berl). 2016 233(7):1147-55. Epub 2016 Jan 4.
Raeder H, Holter SM, Hartmann AM, Spanagel R, Moller HJ, Rujescu D. Expression of N-methyl-d-aspartate (NMDA) receptor subunits and splice variants in an animal model of long-term voluntary alcohol self-administration. Drug Alcohol Depend. 2008 96(1-2):16-21.
Rauner C, Köhr G. Triheteromeric NR1/NR2A/NR2B receptors constitute the major N-methyl-D-aspartate receptor population in adult hippocampal synapses. J Biol Chem. 2011 286(9):7558-66.
Rebolledo-Solleiro D, Araiza LF, Broccoli L, Hansson AC, Rocha-Arrieta LL, Aguilar-Roblero R, Crespo-Ramirez M, Fuxe K, Perez de la Mora M. Dopamine D1 receptor activity is involved in the increased anxiety levels observed in STZ-induced diabetes in rats. Behav Brain Res. 2016 313:293-301. Epub 2016 Jun 30.
Richiardi J, Altmann A, Milazzo AC, Chang C, Chakravarty MM, Banaschewski T, Barker GJ, Bokde AL, Bromberg U, Büchel C, Conrod P, Fauth-Bühler M, Flor H, Frouin V, Gallinat J, Garavan H, Gowland P, Heinz A, Lemaitre H, Mann KF, Martinot JL, Nees F, Paus T, Pausova Z, Rietschel M, Robbins TW, Smolka MN, Spanagel R, Ströhle A, Schumann G, Hawrylycz M, Poline JB, Greicius MD, Diesch E, Gebicke-Haerter PJ, Kiefer F, Vollstädt-Klein S, Schulze TG, IMAGEN consortium . Correlated gene expression supports synchronous activity in brain networks. Science. 2015 348(6240):1241-4.
Rodriguez Parkitna J, Bilbao A, Rieker C, Engblom D, Piechota M, Nordheim A, Spanagel R, Schütz G. Loss of the serum response factor in the dopamine system leads to hyperactivity. FASEB J. 2010 24(7):2427-35. Epub 2010 Mar 11.
Ruggeri B, Nymberg C, Vuoksimaa E, Lourdusamy A, Wong CP, Carvalho FM, Jia T, Cattrell A, Macare C, Banaschewski T, Barker GJ, Bokde AL, Bromberg U, Büchel C, Conrod PJ, Fauth-Bühler M, Flor H, Frouin V, Gallinat J, Garavan H, Gowland P, Heinz A, Ittermann B, Martinot JL, Nees F, Pausova Z, Paus T, Rietschel M, Robbins T, Smolka MN, Spanagel R, Bakalkin G, Mill J, Sommer WH, Rose RJ, Yan J, Aliev F, Dick D, Kaprio J, Desrivieres S, Schumann G, Vollstädt-Klein S, Millenet S, Grimmer Y, IMAGEN Consortium . Association of Protein Phosphatase PPM1G With Alcohol Use Disorder and Brain Activity During Behavioral Control in a Genome-Wide Methylation Analysis. Am J Psychiatry. 2015 172(6):543-52. Epub 2015 May 18.
Salgado H, Köhr G, Treviño M. Noradrenergic 'tone' determines dichotomous control of cortical spike-timing-dependent plasticity. Sci Rep. 2012 2:417.
Sanchis-Segura C, Borchardt T, Vengeliene V, Zghoul T, Bachteler D, Gass P, Sprengel R, Spanagel R. Involvement of the AMPA receptor GluR-C subunit in alcohol-seeking behavior and relapse. J Neurosci. 2006 26(4):1231-8.
Sanchis-Segura C, Cline B, Jurd R, Rudolph U, Spanagel R. Etomidate and propofol-hyposensitive GABAA receptor beta3(N265M) mice show little changes in acute alcohol sensitivity but enhanced tolerance and withdrawal. Neurosci Lett. 2007 416(3):275-8.
Sanchis-Segura C, Spanagel R. Behavioural assessment of drug reinforcement and addictive features in rodents: an overview. Addict Biol. 2006 11(1):2-38.
Schmahl C, Herpertz SC, Bertsch K, Ende G, Flor H, Kirsch P, Lis S, Meyer-Lindenberg A, Rietschel M, Schneider M, Spanagel R, Treede RD, Bohus M. Mechanisms of disturbed emotion processing and social interaction in Borderline Personality Disorder. BPDED. 2014 1(12):12.
Schmitt A, Leonardi-Essmann F, Durrenberger PF, Parlapani E, Schneider-Axmann T, Spanagel R, Arzberger T, Kretzschmar H, Herrera-Marschitz M, Gruber O, Reynolds R, Falkai P, Gebicke-Haerter PJ. Regulation of immune-modulatory genes in left superior temporal cortex of schizophrenia patients: a genome-wide microarray study. World J Biol Psychiatry. 2011 12(3):201-15. Epub 2010 Nov 22.
Schmitt A, Leonardi-Essmann F, Durrenberger PF, Wichert SP, Spanagel R, Arzberger T, Kretzschmar H, Zink M, Herrera-Marschitz M, Reynolds R, Rossner MJ, Falkai P, Gebicke-Haerter PJ. Structural synaptic elements are differentially regulated in superior temporal cortex of schizophrenia patients. Eur Arch Psychiatry Clin Neurosci. 2012 262(7):565-77. Epub 2012 Mar 23.
Schneider M. Cannabis use in pregnancy and early life and its consequences: animal models. Eur Arch Psychiatry Clin Neurosci. 2009 259(7):383-93.
Schneider M. Puberty as a highly vulnerable developmental period for the consequences of cannabis exposure. Addict Biol. 2008 13(2):253-63.
Schneider M. Adolescence as a vulnerable period to alter rodent behavior. Cell Tissue Res. 2013 354(1):99-106.
Schneider M, Drews E, Koch M. Behavioral effects in adult rats of chronic prepubertal treatment with the cannabinoid receptor agonist WIN 55,212-2. Behav Pharmacol. 2005 16(5-6):447-54.
Schneider M, Heise V, Spanagel R. Differential involvement of the opioid receptor antagonist naloxone in motivational and hedonic aspects of reward. Behav Brain Res. 2010 208(2):466-72. Epub 2009 Dec 24.
Schneider M, Kasanetz F, Lynch DL, Friemel CM, Lassalle O, Hurst DP, Steindel F, Monory K, Schäfer C, Miederer I, Leweke FM, Schreckenberger M, Lutz B, Reggio PH, Manzoni OJ, Spanagel R. Enhanced Functional Activity of the Cannabinoid Type-1 Receptor Mediates Adolescent Behavior. J Neurosci. 2015 35(41):13975-88.
Schneider M, Koch M. Behavioral and morphological alterations following neonatal excitotoxic lesions of the medial prefrontal cortex in rats. Exp Neurol. 2005 195(1):185-98.
Schneider M, Koch M. The effect of chronic peripubertal cannabinoid treatment on deficient object recognition memory in rats after neonatal mPFC lesion. Eur Neuropsychopharmacol. 2007 17(3):180-6.
Schneider M, Koch M. Deficient social and play behavior in juvenile and adult rats after neonatal cortical lesion: effects of chronic pubertal cannabinoid treatment. Neuropsychopharmacology. 2005 30(5):944-57.
Schneider M, Koch M. Chronic pubertal, but not adult chronic cannabinoid treatment impairs sensorimotor gating, recognition memory, and the performance in a progressive ratio task in adult rats. Neuropsychopharmacology. 2003 28(10):1760-9.
Schneider M, Koch M. The cannabinoid agonist WIN 55,212-2 reduces sensorimotor gating and recognition memory in rats. Behav Pharmacol. 2002 13(1):29-37.
Schneider M, Schömig E, Leweke FM. Acute and chronic cannabinoid treatment differentially affects recognition memory and social behavior in pubertal and adult rats. Addict Biol. 2008 13(3-4):345-57.
Schneider M, Spanagel R. Appetitive odor-cue conditioning attenuates the acoustic startle response in rats. Behav Brain Res. 2008 189(1):226-30.
Schneider M, Spanagel R, Zhang SJ, Bading H, Klugmann M. Adeno-associated virus (AAV)-mediated suppression of Ca2+/calmodulin kinase IV activity in the nucleus accumbens modulates emotional behaviour in mice. BMC Neurosci. 2007 8:105.
Schneider P, Bindila L, Schmahl C, Bohus M, Meyer-Lindenberg A, Lutz B, Spanagel R, Schneider M. Adverse Social Experiences in Adolescent Rats Result in Enduring Effects on Social Competence, Pain Sensitivity and Endocannabinoid Signaling. Front Behav Neurosci. 2016 10:203.
Schneider P, Hannusch C, Schmahl C, Bohus M, Spanagel R, Schneider M. Adolescent peer-rejection persistently alters pain perception and CB1 receptor expression in female rats. Eur Neuropsychopharmacol. 2014 24(2):290-301. Epub 2013 May 10.
Schneider P, Ho YJ, Spanagel R, Pawlak CR. A novel elevated plus-maze procedure to avoid the one-trial tolerance problem. Front Behav Neurosci. 2011 5:43.
Schneider P, Pätz M, Spanagel R, Schneider M. Adolescent social rejection alters pain processing in a CB1 receptor dependent manner. Eur Neuropsychopharmacol. 2016 26(7):1201-12. Epub 2016 May 2.
Schneider P, Weber-Fahr W, Schweinfurth N, Ho YJ, Sartorius A, Spanagel R, Pawlak CR. Central metabolite changes and activation of microglia after peripheral interleukin-2 challenge. Brain Behav Immun. 2012 26(2):277-83. Epub 2011 Sep 29.
Schneider S, Peters J, Bromberg U, Brassen S, Menz MM, Miedl SF, Loth E, Banaschewski T, Barbot A, Barker G, Conrod PJ, Dalley JW, Flor H, Gallinat J, Garavan H, Heinz A, Itterman B, Mallik C, Mann K, Artiges E, Paus T, Poline JB, Rietschel M, Reed L, Smolka MN, Spanagel R, Speiser C, Ströhle A, Struve M, Schumann G, Büchel C, IMAGEN consortium . Boys do it the right way: sex-dependent amygdala lateralization during face processing in adolescents. Neuroimage. 2011 56(3):1847-53.
Schneider S, Peters J, Bromberg U, Brassen S, Miedl SF, Banaschewski T, Barker GJ, Conrod P, Flor H, Garavan H, Heinz A, Ittermann B, Lathrop M, Loth E, Mann K, Martinot JL, Nees F, Paus T, Rietschel M, Robbins TW, Smolka MN, Spanagel R, Ströhle A, Struve M, Schumann G, Büchel C, the IMAGEN Consortium . Risk Taking and the Adolescent Reward System: A Potential Common Link to Substance Abuse. Am J Psychiatry. 2012 169(1):39-46.
Scholz R, Berberich S, Rathgeber L, Kolleker A, Köhr G, Kornau HC. AMPA receptor signaling through BRAG2 and Arf6 critical for long-term synaptic depression. Neuron. 2010 66(5):768-80.
Schumann G, Coin LJ, Lourdusamy A, Charoen P, Berger KH, Stacey D, Desrivieres S, Aliev FA, Khan AA, Amin N, Aulchenko YS, Bakalkin G, Bakker SJ, Balkau B, Beulens JW, Bilbao A, de Boer RA, Beury D, Bots ML, Breetvelt EJ, Cauchi S, Cavalcanti-Proença C, Chambers JC, Clarke TK, Dahmen N, de Geus EJ, Dick D, Ducci F, Easton A, Edenberg HJ, Esk T, Fernández-Medarde A, Foroud T, Freimer NB, Girault JA, Grobbee DE, Guarrera S, Gudbjartsson DF, Hartikainen AL, Heath AC, Hesselbrock V, Hofman A, Hottenga JJ, Isohanni MK, Kaprio J, Khaw KT, Kuehnel B, Laitinen J, Lobbens S, Luan J, Mangino M, Maroteaux M, Matullo G, McCarthy MI, Mueller C, Navis G, Numans ME, Núñez A, Nyholt DR, Onland-Moret CN, Oostra BA, O'Reilly PF, Palkovits M, Penninx BW, Polidoro S, Pouta A, Prokopenko I, Ricceri F, Santos E, Smit JH, Soranzo N, Song K, Sovio U, Stumvoll M, Surakk I, Thorgeirsson TE, Thorsteinsdottir U, Troakes C, Tyrfingsson T, Tönjes A, Uiterwaal CS, Uitterlinden AG, van der Harst P, van der Schouw YT, Staehlin O, Vogelzangs N, Vollenweider P, Waeber G, Wareham NJ, Waterworth DM, Whitfield JB, Wichmann EH, Willemsen G, Witteman JC, Yuan X, Zhai G, Zhao JH, Zhang W, Martin NG, Metspalu A, Doering A, Scott J, Spector TD, Loos RJ, Boomsma DI, Mooser V, Peltonen L, Stefansson K, van Duijn CM, Vineis P, Sommer WH, Kooner JS, Spanagel R, Heberlein UA, Jarvelin MR, Elliott P. Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption. Proc Natl Acad Sci U S A. 2011 108(17):7119-24. Epub 2011 Apr 6.
Schumann G, Johann M, Frank J, Preuss U, Dahmen N, Laucht M, Rietschel M, Rujescu D, Lourdusamy A, Clarke TK, Krause K, Dyer A, Depner M, Wellek S, Treutlein J, Szegedi A, Giegling I, Cichon S, Blomeyer D, Heinz A, Heath S, Lathrop M, Wodarz N, Soyka M, Spanagel R, Mann K. Systematic analysis of glutamatergic neurotransmission genes in alcohol dependence and adolescent risky drinking behavior. Arch Gen Psychiatry. 2008 65(7):826-38.
Schumann G, Loth E, Banaschewski T, Barbot A, Barker G, Büchel C, Conrod PJ, Dalley JW, Flor H, Gallinat J, Garavan H, Heinz A, Itterman B, Lathrop M, Mallik C, Mann K, Martinot JL, Paus T, Poline JB, Robbins TW, Rietschel M, Reed L, Smolka M, Spanagel R, Speiser C, Stephens DN, Ströhle A, Struve M, IMAGEN consortium . The IMAGEN study: reinforcement-related behaviour in normal brain function and psychopathology. Mol Psychiatry. 2010 15(12):1128-39.
Segnitz N, Ferbert T, Schmitt A, Gass P, Gebicke-Haerter PJ, Zink M. Effects of chronic oral treatment with aripiprazole on the expression of NMDA receptor subunits and binding sites in rat brain. Psychopharmacology (Berl). 2011 217(1):127-42. Epub 2011 Apr 12.
Segnitz N, Schmitt A, Gebicke-Härter PJ, Zink M. Differential expression of glutamate transporter genes after chronic oral treatment with aripiprazole in rats. Neurochem Int. 2009 55(7):619-28. Epub 2009 Jun 12.
Sellmann C, Pildaín LV, Schmitt A, Leonardi-Essmann F, Durrenberger PF, Spanagel R, Arzberger T, Kretzschmar H, Zink M, Gruber O, Herrera-Marschitz M, Reynolds R, Falkai P, Gebicke-Haerter PJ, Matthäus F. Gene expression in superior temporal cortex of schizophrenia patients. Eur Arch Psychiatry Clin Neurosci. 2014 264(4):297-309. Epub 2013 Nov 28.
Shin J, Bourdon C, Bernard M, Wilson MD, Reischl E, Waldenberger M, Ruggeri B, Schumann G, Desrivieres S, Leemans A, IMAGEN Consortium , SYS Consortium , Abrahamowicz M, Leonard G, Richer L, Bouchard L, Gaudet D, Paus T, Pausova Z, Vollstädt-Klein S, Banaschewski T, Flor H, Rietschel M, Spanagel R, Nees F, Fauth-Bühler M, Millenet S, Grimmer Y, The IMAGEN Consortium . Layered genetic control of DNA methylation and gene expression: a locus of multiple sclerosis in healthy individuals. Hum Mol Genet. 2015 24(20):5733-45.
Sillaber I, Rammes G, Zimmermann S, Mahal B, Zieglgänsberger W, Wurst W, Holsboer F, Spanagel R. Enhanced and delayed stress-induced alcohol drinking in mice lacking functional CRH1 receptors. Science. 2002 296(5569):931-3.
Sommer JU, Schmitt A, Heck M, Schaeffer EL, Fendt M, Zink M, Nieselt K, Symons S, Petroianu G, Lex A, Herrera-Marschitz M, Spanagel R, Falkai P, Gebicke-Haerter PJ. Differential expression of presynaptic genes in a rat model of postnatal hypoxia: relevance to schizophrenia. Eur Arch Psychiatry Clin Neurosci. 2010 260 Suppl 2:S81-9.
Sommer W, Spanagel R. Behavioral neurobiology of alcohol addiction. Preface. Curr Top Behav Neurosci. 2013 13:v-vii.
Sommer WH, Costa RM, Hansson AC. Dopamine systems adaptation during acquisition and consolidation of a skill. Front Integr Neurosci. 2014 8:87.
Sommer WH, Lidström J, Sun H, Passer D, Eskay R, Parker SC, Witt SH, Zimmermann US, Nieratschker V, Rietschel M, Margulies EH, Palkovits M, Laucht M, Heilig M. Human NPY promoter variation rs16147:T>C as a moderator of prefrontal NPY gene expression and negative affect. Hum Mutat. 2010 31(8):E1594-608.
Sommer WH, Rimondini R, Hansson AC, Hipskind PA, Gehlert DR, Barr CS, Heilig MA. Upregulation of voluntary alcohol intake, behavioral sensitivity to stress, and amygdala crhr1 expression following a history of dependence. Biol Psychiatry. 2008 63(2):139-45.
Spanagel R. A call for systems approaches in addiction research. Addiction. 2010 105(5):791-2; discussion 795-6.
Spanagel R. Are metabotropic glutamate receptors promising targets for the treatment of alcoholism?. Biol Psychiatry. 2010 67(9):798-9.
Spanagel R. Science meets public. Addict Biol. 2006 11(1):1.
Spanagel R. Alcoholism: a systems approach from molecular physiology to addictive behavior. Physiol Rev. 2009 89(2):649-705.
Spanagel R. Why do we take drugs? From the drug-reinforcement theory to a novel concept of drug instrumentalization. Behav Brain Sci. 2011 34(6):322.
Spanagel R. Convergent functional genomics in addiction research - a translational approach to study candidate genes and gene networks. In Silico Pharmacol. 2013 1:18.
Spanagel R, Bartsch D, Brors B, Dahmen N, Deussing J, Eils R, Ende G, Gallinat J, Gebicke-Haerter P, Heinz A, Kiefer F, Jäger W, Mann K, Matthäus F, Nöthen M, Rietschel M, Sartorius A, Schütz G, Sommer WH, Sprengel R, Walter H, Wichmann E, Wienker T, Wurst W, Zimmer A. An integrated genome research network for studying the genetics of alcohol addiction. Addict Biol. 2010 15(4):369-379.
Spanagel R, Bohus M. Disruption of reconsolidation processes is a balancing act - can it really account for change in psychotherapy?. Behav Brain Sci. 2015 38:e25.
Spanagel R, Durstewitz D, Hansson A, Heinz A, Kiefer F, Köhr G, Matthäus F, Nöthen MM, Noori HR, Obermayer K, Rietschel M, Schloss P, Scholz H, Schumann G, Smolka M, Sommer W, Vengeliene V, Walter H, Wurst W, Zimmermann US, Stringer S, Smits Y, Derks EM. A systems medicine research approach for studying alcohol addiction. Addict Biol. 2013 18(6):883-96.
Spanagel R, Herz A, Shippenberg TS. Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathway. Proc Natl Acad Sci U S A. 1992 89(6):2046-50.
Spanagel R, Kiefer F. Drugs for relapse prevention of alcoholism: ten years of progress. Trends Pharmacol Sci. 2008 29(3):109-15.
Spanagel R, Koob GF, le Moal M. Neurobiology of addiction : book review . Addiction. 2007 102:493.
Spanagel R, Noori HR, Heilig M. Stress and alcohol interactions: animal studies and clinical significance. Trends Neurosci. 2014 37(4):219-227. Epub 2014 Mar 10.
Spanagel R, Pendyala G, Abarca C, Zghoul T, Sanchis-Segura C, Magnone MC, Lascorz J, Depner M, Holzberg D, Soyka M, Schreiber S, Matsuda F, Lathrop M, Schumann G, Albrecht U. The clock gene Per2 influences the glutamatergic system and modulates alcohol consumption. Nat Med. 2005 11(1):35-42.
Spanagel R, Schneider M. Cannabinoids and adolescent behaviour. Pharmacol Rep. 2014 66(2):331.
Spanagel R, Vengeliene V. New Pharmacological Treatment Strategies for Relapse Prevention. Curr Top Behav Neurosci. 2013 13:583-609. Epub 2012 Mar 3.
Spanagel R, Vengeliene V, Jandeleit B, Fischer WN, Grindstaff K, Zhang X, Gallop MA, Krstew EV, Lawrence AJ, Kiefer F. Acamprosate Produces its Anti-Relapse Effects via Calcium. Neuropsychopharmacology. 2014 39(4):783-91. Epub 2013 Sep 30.
Spanagel R, Vengeliene V, Kiefer F. Reply to: Does acamprosate really produce its anti-relapse effects via calcium? No support from the PREDICT study in human alcoholics. Neuropsychopharmacology. 2016 41(3):661-2.
Spechler PA, Orr CA, Chaarani B, Kan KJ, Mackey S, Morton A, Snowe MP, Hudson KE, Althoff RR, Higgins ST, Cattrell A, Flor H, Nees F, Banaschewski T, Bokde AL, Whelan R, Büchel C, Bromberg U, Conrod P, Frouin V, Papadopoulos D, Gallinat J, Heinz A, Walter H, Ittermann B, Gowland P, Paus T, Poustka L, Martinot JL, Artiges E, Smolka MN, Schumann G, Garavan H, Schulze TG, Rietschel M, Diesch E, Gebicke-Haerter PJ, Kiefer F, Vollstädt-Klein S, Spanagel R, IMAGEN Consortium . Cannabis use in early adolescence: Evidence of amygdala hypersensitivity to signals of threat. Dev Cogn Neurosci. 2015 16:63-70. Epub 2015 Aug 28.
Sreedharan S, Almén MS, Carlini VP, Haitina T, Stephansson O, Sommer WH, Heilig M, de Barioglio SR, Fredriksson R, Schiöth HB. The G protein coupled receptor Gpr153 shares common evolutionary origin with Gpr162 and is highly expressed in central regions including the thalamus, cerebellum and the arcuate nucleus. FEBS J. 2011 278(24):4881-94. Epub 2011 Oct 31.
Stacey D, Bilbao A, Maroteaux M, Jia T, Easton AC, Longueville S, Nymberg C, Banaschewski T, Barker GJ, Büchel C, Carvalho F, Conrod PJ, Desrivieres S, Fauth-Bühler M, Fernández-Medarde A, Flor H, Gallinat J, Garavan H, Bokde AL, Heinz A, Ittermann B, Lathrop M, Lawrence C, Loth E, Lourdusamy A, Mann KF, Martinot JL, Nees F, Palkovits M, Paus T, Pausova Z, Rietschel M, Ruggeri B, Santos E, Smolka MN, Staehlin O, Jarvelin MR, Elliott P, Sommer WH, Mameli M, Müller CP, Spanagel R, Girault JA, Schumann G, the IMAGEN Consortium , IMAGEN Consortium . RASGRF2 regulates alcohol-induced reinforcement by influencing mesolimbic dopamine neuron activity and dopamine release. Proc Natl Acad Sci U S A. 2012 109(51):21128-33. Epub 2012 Dec 5..
Stacey D, Lourdusamy A, Ruggeri B, Maroteaux M, Jia T, Cattrell A, Nymberg C, Banaschewski T, Bhattacharyya S, Band H, Barker G, Bokde A, Büchel C, Carvalho F, Conrod P, Desrivieres S, Easton A, Fauth-Buehler M, Fernández-Medarde A, Flor H, Frouin V, Gallinat J, Garavanh H, Heinz A, Ittermann B, Lathrop M, Lawrence C, Loth E, Mann K, Martinot JL, Nees F, Paus T, Pausova Z, Rietschel M, Rotter A, Santos E, Smolka M, Sommer W, Mameli M, Spanagel R, Girault JA, Mueller C, Schumann G, Diesch E, Gebicke-Haerter PJ, Kiefer F, Vollstädt-Klein S, Poustka L, Schulze TG, IMAGEN consortium . A translational systems biology approach in both animals and humans identifies a functionally related module of accumbal genes involved in the regulation of reward processing and binge drinking in males. J Psychiatry Neurosci. 2016 41:192-202. Epub 2015 Dec 11.
Steigerwald F, Schulz TW, Schenker LT, Kennedy MB, Seeburg PH, Köhr G. C-Terminal truncation of NR2A subunits impairs synaptic but not extrasynaptic localization of NMDA receptors. J Neurosci. 2000 20(12):4573-81.
Stickel F, Buch S, Lau K, Zu Schwabedissen HM, Berg T, Ridinger M, Rietschel M, Schafmayer C, Braun F, Hinrichsen H, Günther R, Arlt A, Seeger M, Müller S, Seitz HK, Soyka M, Lerch M, Lammert F, Sarrazin C, Kubitz R, Häussinger D, Hellerbrand C, Bröring D, Schreiber S, Kiefer F, Spanagel R, Mann K, Datz C, Krawczak M, Wodarz N, Völzke H, Hampe J. Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians. Hepatology. 2011 53(1):86-95. Epub 2010 Dec 7.
Stopponi S, Somaini L, Cippitelli A, de Guglielmo G, Kallupi M, Cannella N, Gerra G, Massi M, Ciccocioppo R. Pregabalin reduces alcohol drinking and relapse to alcohol seeking in the rat. Psychopharmacology (Berl). 2012 220(1):87-96.
Stringaris A, Vidal-Ribas Belil P, Artiges E, Lemaitre H, Gollier-Briant F, Wolke S, Vulser H, Miranda R, Penttilä J, Struve M, Fadai T, Kappel V, Grimmer Y, Goodman R, Poustka L, Conrod P, Cattrell A, Banaschewski T, Bokde AL, Bromberg U, Büchel C, Flor H, Frouin V, Gallinat J, Garavan H, Gowland P, Heinz A, Ittermann B, Nees F, Papadopoulos D, Paus T, Smolka MN, Walter H, Whelan R, Martinot JL, Schumann G, Paillere-Martinot ML, Gebicke-Haerter PJ, Kiefer F, Diesch E, Vollstädt-Klein S, Rietschel M, Schulze TG, Spanagel R, IMAGEN Consortium . The Brain's Response to Reward Anticipation and Depression in Adolescence: Dimensionality, Specificity, and Longitudinal Predictions in a Community-Based Sample. Am J Psychiatry. 2015 172(12):1215-23. Epub 2015 Jun 18.
Tapocik JD, Solomon M, Flanigan M, Meinhardt M, Barbier E, Schank JR, Schwandt M, Sommer WH, Heilig M. Coordinated dysregulation of mRNAs and microRNAs in the rat medial prefrontal cortex following a history of alcohol dependence. Pharmacogenomics J. 2013 13(3):286-96. Epub 2012 May 22.
Tews B, Schönig K, Arzt ME, Clementi S, Rioult-Pedotti MS, Zemmar A, Berger SM, Schneider M, Enkel T, Weinmann O, Kasper H, Schwab ME, Bartsch D. Synthetic microRNA-mediated downregulation of Nogo-A in transgenic rats reveals its role as regulator of synaptic plasticity and cognitive function. Proc Natl Acad Sci U S A. 2013 110(16):6583-8. Epub 2013 Apr 1.
Toro R, Poline JB, Huguet G, Loth E, Frouin V, Banaschewski T, Barker GJ, Bokde A, Büchel C, Carvalho FM, Conrod P, Fauth-Bühler M, Flor H, Gallinat J, Garavan H, Gowland P, Heinz A, Ittermann B, Lawrence C, Lemaitre H, Mann K, Nees F, Paus T, Pausova Z, Rietschel M, Robbins T, Smolka MN, Ströhle A, Schumann G, Bourgeron T, Vollstädt-Klein S, Spanagel R, Millenet S, Grimmer Y, The IMAGEN Consortium . Genomic architecture of human neuroanatomical diversity. Mol Psychiatry. 2015 20(8):1011-6. Epub 2014 Sep 16.
Tretter F, Gebicke-Haerter PJ. Systems biology in psychiatric research: from complex data sets over wiring diagrams to computer simulations. Methods Mol Biol. 2012 829:567-92.
Tretter F, Gebicke-Haerter PJ, an der Heiden U, Rujescu D, Mewes HW, Turck CW. Affective disorders as complex dynamic diseases--a perspective from systems biology. Pharmacopsychiatry. 2011 44 Suppl 1:S2-8.
Treutlein J, Cichon S, Ridinger M, Wodarz N, Soyka M, Zill P, Maier W, Moessner R, Gaebel W, Dahmen N, Fehr C, Scherbaum N, Steffens M, Ludwig KU, Frank J, Wichmann HE, Schreiber S, Dragano N, Sommer WH, Leonardi-Essmann F, Lourdusamy A, Gebicke-Haerter P, Wienker TF, Sullivan PF, Nöthen MM, Kiefer F, Spanagel R, Mann K, Rietschel M. Genome-wide association study of alcohol dependence. Arch Gen Psychiatry. 2009 66(7):773-84.
Treutlein J, Kissling C, Frank J, Wiemann S, Dong L, Depner M, Saam C, Lascorz J, Soyka M, Preuss UW, Rujescu D, Skowronek MH, Rietschel M, Spanagel R, Heinz A, Laucht M, Mann K, Schumann G. Genetic association of the human corticotropin releasing hormone receptor 1 (CRHR1) with binge drinking and alcohol intake patterns in two independent samples. Mol Psychiatry. 2006 11(6):594-602.
Treviño M, Aguilar-Garnica E, Jendritza P, Li SB, Oviedo T, Köhr G, De Marco RJ. Discrimination learning with variable stimulus 'salience'. Int Arch Med. 2011 4(1):26.
Treviño M, Frey S, Köhr G. Alpha-1 adrenergic receptors gate rapid orientation-specific reduction in visual discrimination. Cereb Cortex. 2012 22(11):2529-41.
Treviño M, Oviedo T, Jendritza P, Li SB, Köhr G, De Marco RJ. Controlled variations in stimulus similarity during learning determine visual discrimination capacity in freely moving mice. Sci Rep. 2013 3:1048_1-13.
Uhrig S, Hirth N, Broccoli L, von Wilmsdorff M, Bauer M, Sommer C, Zink M, Steiner J, Frodl T, Malchow B, Falkai P, Spanagel R, Hansson AC, Schmitt A. Reduced oxytocin receptor gene expression and binding sites in different brain regions in schizophrenia: A post-mortem study. Schizophr Res. 2016 177(1-3):59-66. Epub 2016 Apr 25.
Umhau JC, Momenan R, Schwandt ML, Singley E, Lifshitz M, Doty L, Adams LJ, Vengeliene V, Spanagel R, Zhang Y, Shen J, George DT, Hommer D, Heilig M. Effect of acamprosate on magnetic resonance spectroscopy measures of central glutamate in detoxified alcohol-dependent individuals: a randomized controlled experimental medicine study. Arch Gen Psychiatry. 2010 67(10):1069-77.
Vengeliene V, Bessiere B, Pype J, Spanagel R. The Effects of Xenon and Nitrous Oxide Gases on Alcohol Relapse. Alcohol Clin Exp Res. 2014 83(2):557-63. Epub 2013 Oct 7.
Vengeliene V, Bilbao A, Molander A, Spanagel R. Neuropharmacology of alcohol addiction. Br J Pharmacol. 2008 154(2):299-315.
Vengeliene V, Bilbao A, Spanagel R. The alcohol deprivation effect model for studying relapse behavior: A comparison between rats and mice. Alcohol. 2014 48(3):313-320.
Vengeliene V, Cannella N, Takahashi T, Spanagel R. Metabolic shift of the kynurenine pathway impairs alcohol and cocaine seeking and relapse. Psychopharmacology (Berl). 2016 233(18):3449-59. Epub 2016 Jul 30.
Vengeliene V, Celerier E, Chaskiel L, Penzo F, Spanagel R. Compulsive alcohol drinking in rodents. Addict Biol. 2009 14(4):384-96.
Vengeliene V, Heidbreder CA, Spanagel R. The effects of lamotrigine on alcohol seeking and relapse. Neuropharmacology. 2007 53(8):951-7.
Vengeliene V, Kiefer F, Spanagel R. D-cycloserine facilitates extinction of conditioned alcohol-seeking behaviour in rats. Alcohol Alcohol. 2008 43(6):626-9.
Vengeliene V, Leonardi-Essmann F, Perreau-Lenz SP, Gebicke-Haerter P, Drescher K, Gross G, Spanagel R. The dopamine D3 receptor plays an essential role in alcohol-seeking and relapse. FASEB J. 2006 20(13):2223-33.
Vengeliene V, Leonardi-Essmann F, Sommer WH, M Marston H, Spanagel R. Glycine Transporter-1 Blockade Leads to Persistently Reduced Relapse-like Alcohol Drinking in Rats. Biol Psychiatry. 2010 68(8):704-11. Epub 2010 Jul 23.
Vengeliene V, Moeller A, Meinhardt MW, Beardsley PM, Sommer WH, Spanagel R, Bespalov A. The Calpain Inhibitor A-705253 Attenuates Alcohol-Seeking and Relapse with Low Side-Effect Profile. Neuropsychopharmacology. 2016 41(4):979-88. Epub 2015 Jul 28.
Vengeliene V, Noori HR, Spanagel R. The Use of a Novel Drinkometer System for Assessing Pharmacological Treatment Effects on Ethanol Consumption in Rats. Alcohol Clin Exp Res. 2013 37(Suppl 1):E322-8. Epub 2012 Jul 3.
Vengeliene V, Noori HR, Spanagel R. Activation of Melatonin Receptors Reduces Relapse-Like Alcohol Consumption. Neuropsychopharmacology. 2015 40(13):2897-906. Eoub 2015 May 21.
Vengeliene V, Olevska A, Spanagel R. Long-lasting effect of NMDA receptor antagonist memantine on ethanol-cue association and relapse. J Neurochem. 2015 135(6):1080-5. epub 2015 Sep 22.
Vulser H, Lemaitre H, Artiges E, Miranda R, Penttilä J, Struve M, Fadai T, Kappel V, Grimmer Y, Goodman R, Stringaris A, Poustka L, Conrod P, Frouin V, Banaschewski T, Barker GJ, Bokde AL, Bromberg U, Büchel C, Flor H, Gallinat J, Garavan H, Gowland P, Heinz A, Ittermann B, Lawrence C, Loth E, Mann K, Nees F, Paus T, Pausova Z, Rietschel M, Robbins TW, Smolka MN, Schumann G, Martinot JL, Paillere-Martinot ML, IMAGEN Consortium www imagen-europe com , Diesch E, Gebicke-Haerter PJ, Kiefer F, Vollstädt-Klein S, Schulze TG, Spanagel R, IMAGEN Consortium (www.imagen-europe.com) . Subthreshold Depression and Regional Brain Volumes in Young Community Adolescents. J Am Acad Child Adolesc Psychiatry. 2015 54(10):832-40.
Waltereit R, Japs B, Schneider M, de Vries PJ, Bartsch D. Epilepsy and Tsc2 Haploinsufficiency Lead to Autistic-Like Social Deficit Behaviors in Rats. Behav Genet. 2011 41(3):364-72. Epub 2010 Oct 7.
Waltereit R, Leimer U, von Bohlen und Halbach O, Panke J, Hölter SM, Garrett L, Wittig K, Schneider M, Schmitt C, Calzada-Wack J, Neff F, Becker L, Prehn C, Kutscherjawy S, Endris V, Bacon C, Fuchs H, Gailus-Durner V, Berger S, Schönig K, Adamski J, Klopstock T, Esposito I, Wurst W, de Angelis MH, Rappold G, Wieland T, Bartsch D. Srgap3-/- mice present a neurodevelopmental disorder with schizophrenia-related intermediate phenotypes. FASEB J. 2012 26(11):4418-28. Epub 2012 Jul 20..
Wang WF, Wu SL, Liou YM, Wang AL, Pawlak CR, Ho YJ. MPTP lesion causes neuroinflammation and deficits in object recognition in Wistar rats. Behav Neurosci. 2009 123(6):1261-70.
Whelan R, Conrod PJ, Poline JB, Lourdusamy A, Banaschewski T, Barker GJ, Bellgrove MA, Büchel C, Byrne M, Cummins TD, Fauth-Bühler M, Flor H, Gallinat J, Heinz A, Ittermann B, Mann K, Martinot JL, Lalor EC, Lathrop M, Loth E, Nees F, Paus T, Rietschel M, Smolka MN, Spanagel R, Stephens DN, Struve M, Thyreau B, Vollstaedt-Klein S, Robbins TW, Schumann G, Garavan H, the IMAGEN Consortium . Adolescent impulsivity phenotypes characterized by distinct brain networks. Nat Neurosci. 2012 15(6):920-5. Epub 2012 Apr 29.
Whelan R, Watts R, Orr CA, Althoff RR, Artiges E, Banaschewski T, Barker GJ, Bokde AL, Büchel C, Carvalho FM, Conrod PJ, Flor H, Fauth-Bühler M, Frouin V, Gallinat J, Gan G, Gowland P, Heinz A, Ittermann B, Lawrence C, Mann K, Martinot JL, Nees F, Ortiz N, Paillere-Martinot ML, Paus T, Pausova Z, Rietschel M, Robbins TW, Smolka MN, Ströhle A, Schumann G, Garavan H, Sommer WH, Spanagel R, Steiner S, Poustka L, Schmäl C, Struve M, Bach Ch, the IMAGEN Consortium . Neuropsychosocial profiles of current and future adolescent alcohol misusers. Nature. 2014 512(7513):185-9. Epub 2014 Jul 2.
Wieland S, Du D, Oswald MJ, Parlato R, Köhr G, Kelsch W. Phasic Dopaminergic Activity Exerts Fast Control of Cholinergic Interneuron Firing via Sequential NMDA, D2, and D1 Receptor Activation. J Neurosci. 2014 34(35):11549-59.
Wieland S, Schindler S, Huber C, Köhr G, Oswald MJ, Kelsch W. Phasic Dopamine Modifies Sensory-Driven Output of Striatal Neurons through Synaptic Plasticity. J Neurosci. 2015 35(27):9946-56.
Wiens F, Zitzmann A, Lachance MA, Yegles M, Pragst F, Wurst FM, von Holst D, Guan SL, Spanagel R. Chronic intake of fermented floral nectar by wild treeshrews. Proc Natl Acad Sci U S A. 2008 105(30):10426-31.
Witt SH, Sommer WH, Hansson AC, Sticht C, Rietschel M, Witt CC. Comparison of gene expression profiles in the blood, hippocampus and prefrontal cortex of rats. In Silico Pharmacol. 2013 1:15.
Wu SL, Hsu LS, Tu WT, Wang WF, Huang YT, Pawlak CR, Ho YJ. Effects of D-cycloserine on the behavior and ERK activity in the amygdala: role of individual anxiety levels. Behav Brain Res. 2008 187(2):246-53.
Wöckel L, Bertsch T, Koch S, Achtnichts L, Holtmann M, Gretz N, Schmidt M, Poustka F. [The importance of choline and different serum parameters for the course of the anorexia nervosa]. Fortschr Neurol Psychiatr. 2007 75(7):402-12.
Wöckel L, Koch S, Stadler C, Meyer-Keitel AE, Schmidt M. Serotonin-induced platelet intracellular Ca2+ response in patients with anorexia nervosa. Pharmacopsychiatry. 2008 41(1):10-6.
Wöckel L, Zepf FD, Koch S, Meyer-Keitel AE, Schmidt M. Serotonin-induced decrease of intracellular Ca(2+) release in platelets of bulimic patients normalizes during treatment. J Neural Transm. 2009 116(1):89-95.
Zghoul T, Abarca C, Sanchis-Segura C, Albrecht U, Schumann G, Spanagel R. Ethanol self-administration and reinstatement of ethanol-seeking behavior in Per1(Brdm1) mutant mice. Psychopharmacology (Berl). 2007 190(1):13-9.
Zieker D, Jenne I, Koenigsrainer I, Zdichavsky M, Nieselt K, Buck K, Zieker J, Beckert S, Glatzle J, Spanagel R, Koenigsrainer A, Northoff H, Loeffler M. Circadian expression of clock- and tumor suppressor genes in human oral mucosa. Cell Physiol Biochem. 2010 26(2):155-66. Epub 2010 Aug 24.
Zieker J, Zieker D, Jatzko A, Dietzsch J, Nieselt K, Schmitt A, Bertsch T, Fassbender K, Spanagel R, Northoff H, Gebicke-Haerter PJ. Differential gene expression in peripheral blood of patients suffering from post-traumatic stress disorder. Mol Psychiatry. 2007 12(2):116-8.
Zimmermann US, Winkelmann PR, Pilhatsch M, Nees JA, Spanagel R, Schulz K. Withdrawal phenomena and dependence syndrome after the consumption of "spice gold". Dtsch Arztebl Int. 2009 106(27):464-7.
Zink M, Araç G, Frank ST, Gass P, Gebicke-Härter PJ, Spanagel R. Perinatal exposure to alcohol reduces the expression of complexin I and II. Neurotoxicol Teratol. 2009 31(6):400-5. Epub 2009 Aug 9.
Zink M, Ferbert T, Frank ST, Seufert P, Gebicke-Haerter PJ, Spanagel R. Perinatal exposure to alcohol disturbs spatial learning and glutamate transmission-related gene expression in the adult hippocampus. Eur J Neurosci. 2011 34(3):457-68. Epub 2011 Jul 4..
Zink M, Rapp S, Donev R, Gebicke-Haerter PJ, Thome J. Fluoxetine treatment induces EAAT2 expression in rat brain. J Neural Transm. 2011 118(6):849-55.
Zink M, Vollmayr B, Gebicke-Haerter PJ, Henn FA. Reduced expression of glutamate transporters vGluT1, EAAT2 and EAAT4 in learned helpless rats, an animal model of depression. Neuropharmacology. 2010 58(2):465-73.
Zink M, Vollmayr B, Gebicke-Haerter PJ, Henn FA. Reduced Expression of GABA Transporter GAT3 in Helpless Rats, an Animal Model of Depression. Neurochem Res. 2009 34(9):1584-93. Epub 2009 Mar 15..
Zink M, Vollmayr B, Gebicke-Haerter PJ, Henn FA, Thome J. Reduced expression of complexins I and II in rats bred for learned helplessness. Brain Res. 2007 1144:202-8.
Zlatković J, Bernardi RE, Filipovic D. Protective effect of Hsp70i against chronic social isolation stress in the rat hippocampus. J Neural Transm. 2014 121(1):3-14.
Zlatković J, Todorović N, Tomanović N, Bošković M, Djordjević S, Lazarević-Pašti T, Bernardi RE, Djurdjević A, Filipovic D. Chronic administration of fluoxetine or clozapine induces oxidative stress in rat liver: a histopathological study. Eur J Pharm Sci. 2014 59:20-30.
Zueger M, Urani A, Chourbaji S, Zacher C, Lipp HP, Albrecht U, Spanagel R, Wolfer DP, Gass P. mPer1 and mPer2 mutant mice show regular spatial and contextual learning in standardized tests for hippocampus-dependent learning. J Neural Transm. 2006 113(3):347-56.
de Fonseca FR, Schneider M. The endogenous cannabinoid system and drug addiction: 20 years after the discovery of the CB1 receptor. Addict Biol. 2008 13(2):143-6.
von der Goltz C, Vengeliene V, Bilbao A, Perreau-Lenz SP, Pawlak CR, Kiefer F, Spanagel R. Cue-induced alcohol-seeking behaviour is reduced by disrupting the reconsolidation of alcohol-related memories. Psychopharmacology (Berl). 2009 205(3):389-97. Epub 2009 May 6.


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