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Publikationen: Abhängiges Verhalten und Suchtmedizin

Antonsen KK, Klausen MK, Brunchmann AS, le Dous N, Jensen ME, Miskowiak KW, Fisher PM, Thomsen GK, Rindom H, Fahmy TP, Vollstaedt-Klein S, Benveniste H, Volkow ND, Becker U, Ekstrøm C, Knudsen GM, Vilsbøll T, Fink-Jensen A. Does glucagon-like peptide-1 (GLP-1) receptor agonist stimulation reduce alcohol intake in patients with alcohol dependence: study protocol of a randomised, double-blinded, placebo-controlled clinical trial. BMJ Open. 2018 8(7):e019562.
Bach P, Koopmann A, Hermann D, Kiefer F, Bumb JM. Massive Creatine Kinase Elevation in 2 Patients During Short-Term and Low-Dose Antipsychotic Monotherapy With Quetiapine. J Clin Psychopharmacol. 2018 38(4):385-387. Epub 2018 Jun 12.
Becker A, Gerchen MF, Kirsch M, Hoffmann S, Kiefer F, Kirsch P. Striatal reward sensitivity predicts therapy-related neural changes in alcohol addiction. Eur Arch Psychiatry Clin Neurosci. 2018 268(3):231-242. Epub 2017 May 9.
Bouna-Pyrrou P, Aufleger B, Braun S, Gattnar M, Kallmayer S, Wagner H, Kornhuber J, Mühle C, Lenz B. Cross-Sectional and Longitudinal Evaluation of the Social Network Use Disorder and Internet Gaming Disorder Criteria. Front Psychiatry. 2018 9:692.
Bramness JG, Dom G, Gual A, Mann K, Wurst FM. A Survey on the Medical Use of Cannabis in Europe: A Position Paper. Eur Addict Res. 2018 24(4):201-205.
Braun B, Weinland C, Kornhuber J, Lenz B. Religiosity, Guilt, Altruism and Forgiveness in Alcohol Dependence: Results of a Cross-sectional and Prospective Cohort Study. Alcohol Alcohol. 2018 53(4):426-434.
Broccoli L, Uhrig S, von Jonquieres G, Schönig K, Bartsch D, Justice NJ, Spanagel R, Sommer WH, Klugmann M, Hansson AC. Targeted overexpression of CRH receptor subtype 1 in central amygdala neurons: effect on alcohol-seeking behavior. Psychopharmacology (Berl). 2018 235(6):1821-1833. Epub 2018 Apr 26.
Deuschle M, Schredl M, Wisch C, Schilling C, Gilles M, Geisel O, Hellweg R. Serum brain-derived neurotrophic factor (BDNF) in sleep-disordered patients: relation to sleep stage N3 and rapid eye movement (REM) sleep across diagnostic entities. J Sleep Res. 2018 27(1):73-77. Epub 2017 Jun 28.
Eichler A, Heinrich H, Moll GH, Beckmann MW, Goecke TW, Fasching PA, Muschler MR, Bouna-Pyrrou P, Lenz B, Kornhuber J. Digit ratio (2D:4D) and behavioral symptoms in primary-school aged boys. Early Hum Dev. 2018 119:1-7.
Foo JC, Streit F, Treutlein J, Ripke S, Witt SH, Strohmaier J, Degenhardt F, Forstner AJ, Hoffmann P, Soyka M, Dahmen N, Scherbaum N, Wodarz N, Heilmann-Heimbach S, Herms S, Cichon S, Preuss U, Gaebel W, Ridinger M, Hoffmann S, Schulze TG, Maier W, Zill P, Müller-Myhsok B, Ising M, Lucae S, Nöthen MM, Mann K, Kiefer F, Rietschel M, Frank J, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium . Shared genetic etiology between alcohol dependence and major depressive disorder. Psychiatr Genet. 2018 28(4):66-70. Epub 2018 Jun 12.
Gegenhuber B, Weinland C, Kornhuber J, Mühle C, Lenz B. OPRM1 A118G and serum β-endorphin interact with sex and digit ratio (2D:4D) to influence risk and course of alcohol dependence. Eur Neuropsychopharmacol. 2018 28(12):1418-1428.
Gerchen MF, Kirsch M, Bahs N, Halli P, Gerhardt S, Schäfer A, Sommer WH, Kiefer F, Kirsch P. The SyBil-AA real-time fMRI neurofeedback study: protocol of a single-blind randomized controlled trial in alcohol use disorder. BMC Psychiatry. 2018 18(1):12.
Günthner A, Weissinger V, Fleischmann H, Veltrup C, Jäpel B, Längle G, Amann K, Hoch E, Mann K. [Health Care Organization - The New German S3-Guideline on Alcohol-Related Disorders and its Relevance for Health Care]. Rehabilitation (Stuttg). 2018 47(4):284-293. Epub 2018 Jan 22.
Günthner J, Scholl J, Kiefer F, Reinecke A. Single-dose hydrocortisone administration does not enhance motor sequence learning or reward learning in humans. J Psychopharmacol. 2018 32(5):591-594. Epub 2018 Mar 1.
Hansson AC, Koopmann A, Uhrig S, Bühler S, Domi E, Kiessling E, Ciccocioppo R, Froemke RC, Grinevich V, Kiefer F, Sommer WH, Vollstädt-Klein S, Spanagel R. Oxytocin Reduces Alcohol Cue-Reactivity in Alcohol Dependent Rats and Humans. Neuropsychopharmacology. 2018 43(6):1235-1246. Epub 2017 Nov 1.
Huber SE, Zoicas I, Reichel M, Mühle C, Büttner C, Ekici AB, Eulenburg V, Lenz B, Kornhuber J, Müller CP. Prenatal androgen receptor activation determines adult alcohol and water drinking in a sex-specific way. Addict Biol. 2018 23(3):904-920.
Khalili M, Rahimi-Movaghar A, Shadloo B, Mojtabai R, Mann K, Amin-Esmaeili M. Global Scientific Production on Illicit Drug Addiction: A Two-Decade Analysis. Eur Addict Res. 2018 24(2):60-70. Epub 2018 Apr 6.
Kiefer F. The European Innovation Express: Wim van den Brink Retires as Editor in Chief of European Addiction Research and Will Be Succeeded by Anna E. Goudriaan. Eur Addict Res. 2018 24(3):107-108. Epub 2018 Jun 18.
King DL, Mann KF, Gaming Industry Response Consortium . Comment on the global gaming industry's statement on ICD-11 gaming disorder: a corporate strategy to disregard harm and deflect social responsibility?. Addiction. 2018 113(11):2145-2146.
Knox J, Wall M, Witkiewitz K, Kranzler HR, Falk D, Litten R, Mann K, O'Malley SS, Scodes J, Anton R, Hasin DS, Alcohol Clinical Trials (ACTIVE) Workgroup . Reduction in non-abstinent WHO drinking risk levels and change in risk for liver disease and positive AUDIT-C scores: Prospective 3-year follow-up results in the US general population. Alcohol Clin Exp Res. 2018 42(11):2256-2265. Epub 2018 Sep 11.
Koopmann A, Schuster R, Kiefer F. The impact of the appetite-regulating, orexigenic peptide ghrelin on alcohol use disorders: a systematic review of preclinical and clinical data. Biol Psychol. 2018 131:14-30. Epub 2016 Dec 21..
Kranaster L, Aksay SS, Bumb JM, Hoyer C, Jennen-Steinmetz C, Sartorius A. A novel Seizure Quality Index based on ictal parameters for optimizing clinical decision making in electroconvulsive therapy. Part 1: development. Eur Arch Psychiatry Clin Neurosci. 2018 268(8):819-830. Epub 2018 Jun 6.
Lederbogen F, Ulshöfer E, Peifer A, Fehlner P, Bilek E, Streit F, Deuschle M, Tost H, Meyer-Lindenberg A. No association between cardiometabolic risk and neural reactivity to acute psychosocial stress. Neuroimage Clin. 2018 20:1115-1122. Epub 2018 Oct 22.
Lemenager T, Hoffmann S, Dieter J, Reinhard I, Mann K, Kiefer F. The links between healthy, problematic, and addicted Internet use regarding comorbidities and self-concept-related characteristics. J Behav Addict. 2018 7(1):31-43. Epub 2018 Feb 15.
Lenz B, Bouna-Pyrrou P, Mühle C, Kornhuber J. Low digit ratio (2D:4D) and late pubertal onset indicate prenatal hyperandrogenziation in alcohol binge drinking. Prog Neuropsychopharmacol Biol Psychiatry. 2018 86:370-378.
Lenz B, Eichler A, Schwenke E, Buchholz VN, Hartwig C, Moll GH, Reich K, Mühle C, Volz B, Titzmann A, Beckmann MW, Heinrich H, Kornhuber J, Fasching PA. Mindfulness-based Stress Reduction in Pregnancy: an App-Based Programme to Improve the Health of Mothers and Children (MINDFUL/PMI Study). Geburtshilfe Frauenheilkd. 2018 78(12):1283-1291.
Lenz B, Kornhuber J. Cross-national gender variations of digit ratio (2D:4D) correlate with life expectancy, suicide rate, and other causes of death. J Neural Transm. 2018 125(2):239-246.
Mann K, Roos CR, Hoffmann S, Nakovics H, Leménager T, Heinz A, Witkiewitz K. Precision Medicine in Alcohol Dependence: A Controlled Trial Testing Pharmacotherapy Response among Reward and Relief Drinking Phenotypes. Neuropsychopharmacology. 2018 43(4):891-899. Epub 2017 Nov 20.
Mann K, Roos CR, Witkiewitz K. Response to Letter to Editor (Precision medicine in alcohol dependence: evidence of efficacy and initial support for comparative effectiveness). Neuropsychopharmacology. 2018 43(9):1801-1802. Epub 2018 Jun 12.
Mielenz D, Reichel M, Jia T, Quinlan EB, Stöckl T, Mettang M, Zilske D, Kirmizi-Alsan E, Schönberger P, Praetner M, Huber SE, Amato D, Schwarz M, Purohit P, Brachs S, Spranger J, Heß A, Büttner C, Ekici AB, Perez-Branguli F, Winner B, Rauschenberger V, Banaschewski T, Bokde AL, Büchel C, Conrod PJ, Desrivieres S, Flor H, Frouin V, Gallinat J, Garavan H, Gowland P, Heinz A, Martinot JL, Lemaitre H, Nees F, Paus T, Smolka MN, IMAGEN Consortium , Schambony A, Bäuerle T, Eulenburg V, Alzheimer C, Lourdusamy A, Schumann G, Mann K, Rietschel M, Spanagel R, Fauth-Bühler M, Millenet S, Grimmer Y, Muller CP. EFhd2/Swiprosin-1 is a common genetic determinator for sensation-seeking/low anxiety and alcohol addiction. Mol Psychiatry. 2018 23(5):1303-1317. Epub 2017 Apr 11.
Millenet SK, Nees F, Heintz S, Bach Ch, Frank J, Vollstädt-Klein S, Bokde A, Bromberg U, Büchel C, Quinlan EB, Desrivieres S, Fröhner J, Flor H, Frouin V, Garavan H, Gowland P, Heinz A, Ittermann B, Lemaire H, Martinot JL, Martinot MP, Papadoulos DO, Paus T, Poustka L, Rietschel M, Smolka MN, Walter H, Whelan R, Schumann G, Banaschewski T, Hohmann S. COMT Val158Met Polymorphism and Social Impairment Interactively Affect Attention-Deficit Hyperactivity Symptoms in Healthy Adolescents. Front Genet. 2018 9:284.
Mühle C, Weinland C, Gulbins E, Lenz B, Kornhuber J. Peripheral Acid Sphingomyelinase Activity Is Associated with Biomarkers and Phenotypes of Alcohol Use and Dependence in Patients and Healthy Controls. Int J Mol Sci. 2018 19(12)
Pfarr S, Schaaf L, Reinert JK, Paul E, Herrmannsdörfer F, Roßmanith M, Kuner T, Hansson AC, Spanagel R, Körber C, Sommer WH. Choice for drug or natural reward engages largely overlapping neuronal ensembles in the infralimbic prefrontal cortex. J Neurosci. 2018 38(14):3507-3519. Epub 2018 Feb 24.
Preuss UW, Gouzoulis-Mayfrank E, Havemann-Reinecke U, Schafer I, Beutel M, Hoch E, Mann KF. Psychiatric comorbidity in alcohol use disorders: results from the German S3 guidelines. Eur Arch Psychiatry Clin Neurosci. 2018 268(3):219-229.
Pätz T, Frischknecht U, Dinter C, Reinhard I, Mann KF, Kiefer F, Weber T. Tabakentwöhnung mit kognitiv-behavioraler Gruppentherapie während einer 3-wöchigen qualifizierten Alkoholentzugsbehandlung. Verhaltenstherapie. 2018 28:230-237.
Reinhardt S, Stoye N, Luderer M, Kiefer F, Schmitt U, Lieb K, Endres K. Identification of disulfiram as a secretase-modulating compound with beneficial effects on Alzheimer's disease hallmarks. Sci Rep. 2018 8(1):1329.
Rosendahl J, Kirsten H, Hegyi E, Kovacs P, Weiss FU, Laumen H, Lichtner P, Ruffert C, Chen JM, Masson E, Beer S, Zimmer C, Seltsam K, Algül H, Bühler F, Bruno MJ, Bugert P, Burkhardt R, Cavestro GM, Cichoz-Lach H, Farré A, Frank J, Gambaro G, Gimpfl S, Grallert H, Griesmann H, Grützmann R, Hellerbrand C, Hegyi P, Hollenbach M, Iordache S, Jurkowska G, Keim V, Kiefer F, Krug S, Landt O, Leo MD, Lerch MM, Lévy P, Löffler M, Löhr M, Ludwig M, Macek M, Malats N, Malecka-Panas E, Malerba G, Mann K, Mayerle J, Mohr S, Te Morsche RH, Motyka M, Mueller S, Müller T, Nöthen MM, Pedrazzoli S, Pereira SP, Peters A, Pfützer R, Real FX, Rebours V, Ridinger M, Rietschel M, Rösmann E, Saftoiu A, Schneider A, Schulz HU, Soranzo N, Soyka M, Simon P, Skipworth J, Stickel F, Strauch K, Stumvoll M, Testoni PA, Tönjes A, Werner L, Werner J, Wodarz N, Ziegler M, Masamune A, Mössner J, Férec C, Michl P, P H Drenth J, Witt H, Scholz M, Sahin-Tóth M, all members of the PanEuropean Working group on ACP . Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis. Gut. 2018 67(10):1855-1863. Epub 2017 Jul 28.
Ruggeri B, Macare C, Stopponi S, Jia T, Carvalho FM, Robert G, Banaschewski T, Bokde AL, Bromberg U, Büchel C, Cattrell A, Conrod PJ, Desrivieres S, Flor H, Frouin V, Gallinat J, Garavan H, Gowland P, Heinz A, Ittermann B, Martinot JL, Martinot MP, Nees F, Papadopoulos-Orfanos D, Paus T, Poustka L, Smolka MN, Vetter NC, Walter H, Whelan R, Sommer WH, Bakalkin G, Ciccocioppo R, Schumann G, IMAGEN consortium . Methylation of OPRL1 mediates the effect of psychosocial stress on binge drinking in adolescents. J Child Psychol Psychiatry. 2018 59(6):650-658. Epub 2017 Dec 2.
Rumpf HJ, Achab S, Billieux J, Bowden-Jones H, Carragher N, Demetrovics Z, Higuchi S, King DL, Mann K, Potenza M, Saunders JB, Abbott M, Ambekar A, Aricak OT, Assanangkornchai S, Bahar N, Borges G, Brand M, Chan EM, Chung T, Derevensky J, Kashef AE, Farrell M, Fineberg NA, Gandin C, Gentile DA, Griffiths MD, Goudriaan AE, Grall-Bronnec M, Hao W, Hodgins DC, Ip P, Király O, Lee HK, Kuss D, Lemmens JS, Long J, Lopez-Fernandez O, Mihara S, Petry NM, Pontes HM, Rahimi-Movaghar A, Rehbein F, Rehm J, Scafato E, Sharma M, Spritzer D, Stein DJ, Tam P, Weinstein A, Wittchen HU, Wölfling K, Zullino D, Poznyak V. Including gaming disorder in the ICD-11: The need to do so from a clinical and public health perspective. J Behav Addict. 2018 7(3):556-561. Epub 2018 Jul 16.
Stein DJ, Billieux J, Bowden-Jones H, Grant JE, Fineberg N, Higuchi S, Hao W, Mann K, Matsunaga H, Potenza MN, Rumpf HM, Veale D, Ray R, Saunders JB, Reed GM, Poznyak V. Balancing validity, utility and public health considerations in disorders due to addictive behaviours. World Psychiatry. 2018 17(3):363-364.
Streit F, Treutlein J, Frischknecht U, Hermann D, Mann K, Kiefer F, Sack MS, Hall ASM, Frank J, Witt SH, Foo JC, Degenhardt F, Heilmann-Heimbach S, Nöthen MM, Sommer WH, Spanagel R, Rietschel M, Ende G. Glutamate concentration in the anterior cingulate cortex in alcohol dependence: association with alcohol withdrawal and exploration of contribution from glutamatergic candidate genes. Psychiatr Genet. 2018 28(5):94-95. Epub 2018 Jul 5.
Walters RK, Polimanti R, Johnson EC, McClintick JN, Adams MJ, Adkins AE, Aliev F, Bacanu SA, Batzler A, Bertelsen S, Biernacka JM, Bigdeli TB, Chen LS, Clarke TK, Chou YL, Degenhardt F, Docherty AR, Edwards AC, Fontanillas P, Foo JC, Fox L, Frank J, Giegling I, Gordon S, Hack LM, Hartmann AM, Hartz SM, Heilmann-Heimbach S, Herms S, Hodgkinson C, Hoffmann P, Jan Hottenga J, Kennedy MA, Alanne-Kinnunen M, Konte B, Lahti J, Lahti-Pulkkinen M, Lai D, Ligthart L, Loukola A, Maher BS, Mbarek H, McIntosh AM, McQueen MB, Meyers JL, Milaneschi Y, Palviainen T, Pearson JF, Peterson RE, Ripatti S, Ryu E, Saccone NL, Salvatore JE, Sanchez-Roige S, Schwandt M, Sherva R, Streit F, Strohmaier J, Thomas N, Wang JC, Webb BT, Wedow R, Wetherill L, Wills AG, 23andMe Research Team , Boardman JD, Chen D, Choi DS, Copeland WE, Culverhouse RC, Dahmen N, Degenhardt L, Domingue BW, Elson SL, Frye MA, Gäbel W, Hayward C, Ising M, Keyes M, Kiefer F, Kramer J, Kuperman S, Lucae S, Lynskey MT, Maier W, Mann K, Männistö S, Müller-Myhsok B, Murray AD, Nurnberger JI, Palotie A, Preuss U, Räikkönen K, Reynolds MD, Ridinger M, Scherbaum N, Schuckit MA, Soyka M, Treutlein J, Witt S, Wodarz N, Zill P, Adkins DE, Boden JM, Boomsma DI, Bierut LJ, Brown SA, Bucholz KK, Cichon S, Costello EJ, de Wit H, Diazgranados N, Dick DM, Eriksson JG, Farrer LA, Foroud TM, Gillespie NA, Goate AM, Goldman D, Grucza RA, Hancock DB, Harris KM, Heath AC, Hesselbrock V, Hewitt JK, Hopfer CJ, Horwood J, Iacono W, Johnson EO, Kaprio JA, Karpyak VM, Kendler KS, Kranzler HR, Krauter K, Lichtenstein P, Lind PA, McGue M, MacKillop J, Madden PA, Maes HH, Magnusson P, Martin NG, Medland SE, Montgomery GW, Nelson EC, Nöthen MM, Palmer AA, Pedersen NL, Penninx BWJH, Porjesz B, Rice JP, Rietschel M, Riley BP, Rose R, Rujescu D, Shen PH, Silberg J, Stallings MC, Tarter RE, Vanyukov MM, Vrieze S, Wall TL, Whitfield JB, Zhao H, Neale BM, Gelernter J, Edenberg HJ, Agrawal A. Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders. Nat Neurosci. 2018 21(12):1656-1669.
Witkiewitz K, Kranzler HR, Hallgren KA, O'Malley SS, Falk DE, Litten RZ, Hasin DS, Mann KF, Anton RF. Drinking Risk Level Reductions Associated with Improvements in Physical Health and Quality of Life Among Individuals with Alcohol Use Disorder. Alcohol Clin Exp Res. 2018 42(12):2453-2465. Epub 2018 Nov 5.
Zeng H, Su D, Wang P, Wang M, Vollstädt-Klein S, Chen Q, Ye H. The Action Representation Elicited by Different Types of Drug-Related Cues in Heroin-Abstinent Individuals. Front Behav Neurosci. 2018 12:123.
Zois E, Kiefer F, Vollstädt-Klein S, Leménager T, Mann KF, Fauth-Bühler M. Amygdala grey matter volume increase in gambling disorder with depression symptoms of clinical relevance: a voxel-based morphometry study. Int Gambling Studies. 2018 18(2):259-268. Epub 2018 Mar 26.
van den Brink W, Addolorato G, Aubin HJ, Benyamina A, Caputo F, Dematteis M, Gual A, Lesch OM, Mann K, Maremmani I, Nutt D, Paille F, Perney P, Rehm J, Reynaud M, Simon N, Söderpalm B, Sommer WH, Walter H, Spanagel R. Efficacy and safety of sodium oxybate in alcohol-dependent patients with a very high drinking risk level. Addict Biol. 2018 23(4):969-986.

Zentralinstitut für Seelische Gesundheit (ZI) -