3R Center Rhine-Neckar aims to involve scientists who are already working in experimental animal research or who intend to do so, because they are in the best position to refine their experiments in the [...] Institute of Mental Health (ZI), the Mannheim University Medical Center and the University of Heidelberg, are intensifying their networking in order to further reduce the number of animal experiments and to reduce [...] and the Arts. Pooling existing expertise In Baden-Württemberg and in the Rhine-Neckar region, there are a large number of biomedical research institutions where animal experiments also take place. Therefore

, cognitive and neuroscientific levels, researchers are working to identify the triggers and influencing factors for such loss of control. They are investigating the underlying neurobiological mechanisms [...] each. These include seven SFB/Transregional Collaborative Research Centers (TRR), for which there are several applicant universities. The two Collaborative Research Centers in which the Central Institute [...] University of Heidelberg. Partners in the SFB/TRR 265, which is funded with around 16.3 million euros, are the Charité and the Technical University of Dresden as co-applicants, as well as the Universities of

respective treatment success. From this, models are developed to precisely tailor treatment to individual risk and protective factors. “Mental illnesses are major causes of sick leave and early retirement [...] opportunities. With the generous grant from the Hector Foundation II, optimal research conditions are being created at the Central Institute of Mental Health to take the diagnosis, therapy and prevention [...] their Hector Foundation II . This endows the institute with a sum of €11.5 million for its launch. “We are very pleased that it may be possible to use artificial intelligence methods to identify the causes

such as Caspases are strongly downregulated or shut off completely while protective pathways such as antiapoptotic Bcl-2 family proteins of inhibitors of apoptosis proteins (IAPs) are upregulated. ‘It [...] In this context, the human brain behaves fundamentally different. The vast majority of nerve cells are created before birth and the regenerative capacity of the postnatal human brain is limited to a very [...] safeguarding mechanisms in mature neurons may also in part explain why most neurodegenerative diseases are usually fend off for many decades and only tend to occur with advanced age. Manifestation of neuro

view, the changes in the platform's orientation and methods are at odds with values that promote diversity, freedom and democratic discourse and are no longer compatible with transparent and fact-based scientific

Mannheim. “There are huge gaps in our understanding of clinical depression that limit opportunities to improve outcomes for those affected. Larger and more globally representative studies are vital to provide [...] ancestors. The researchers identified a total of 700 variations in the genetic code of individuals that are associated with the development of depression. Almost half of these variations, which relate to 308 [...] approaches to treatment. The research team highlights the existing drugs pregabalin and modafinil, which are used to treat chronic pain and the sleep disorder narcolepsy respectively, and could potentially also

dedicated teams. As a result, the existing initiatives are now coordinated centrally and the services are being continuously expanded. Today, consultations are held in Arabic, German, English, Russian, Turkish [...] cultural backgrounds and incorporating the individual's migration history are important factors in therapy. Only when these aspects are actively incorporated into the treatment can understanding be achieved [...] Clinic, people with a history of migration are to receive high-quality, guideline-based diagnosis and treatment. Other goals of the team go beyond patient care and are intended to change the entire structure

patients, the process of deposition could be slowed down. The plaques are considered to be a significant characteristic of Alzheimer’s and are one of the causes of the disease. Their exact origin has not yet [...] In this stage of the disease, forgetfulness is at the centre of the symptoms, and those affected are still competent in everyday life. This treatment only makes sense at this stage. Half of the participants [...] Lecanemab, in 7.4 per cent on placebo). A specific side effect of Lecanemab and other amyloid antibodies are abnormalities in the imaging – so-called “amyloid-related imaging abnormalities” (ARIA). These show

benefit from this work. I can only confirm that. The working conditions in psychiatric nursing are in flux. How are you responding to that? Psychiatric nursing is exposed to significant changes at many different [...] multi-colored, we're diverse, we're tolerant, we're "absolutely us"! And because that's the way things are there's a great amount of team spirit. This diversity inspires many colleagues and helps them to mature [...] such as ward-equivalent treatment and the track concept. We act as professionals and as equals and are now sought-after mentors and co-creators across various areas. This is closely linked to the fact that

term, instructions with concrete strategies for reducing addictive cravings are planned in the app. In addition, parents are guided to regularly reflect on their addictive cravings, their feelings and [...] Baden-Württemberg, 250,000 children live in families with an addicted parent. These mothers and fathers are often also affected by other mental illnesses. It is a great challenge for them to remain abstinent [...] However, parents with addiction problems often experience access to these services as difficult and are unable to take advantage of them. They lack the social and/or family support to look after their children