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Dr. Anne Hoffrichter

PostDoc

Department Translational Brain Research

Phone: +49 621 1703-2906

e-mail

Lab Building 3.08

About me

Anne is a bioinformatician and data scientist who works in the Koch and Ladewig groups. She has an MSc in Biology and completed her PhD at the Ludwig-Maximilians-Universität (LMU) in Munich, where she developed a keen interest in high-throughput sequencing and data analysis.

 

Since joining the lab in April 2019, she has supported a wide range of projects, focusing on analysing high-throughput sequencing and high-content microscopy data, as well as tackling other computational challenges at the intersection of biology and informatics.

Publications in peer reviewed journals since 2006

TOP 5 publications:

  1. Zillich L, Gasparotto M, Rossetti AC, Fechtner O, Maillard C, Hoffrichter A, Zillich E, Jabali A, Marsoner F, Artioli A, Wilkens R, Schroeter CB, Hentschel A, Witt SH, Melzer N, Meuth SG, Ruck T, Koch P, Roos A, Bahi-Buisson N, Francis F, Ladewig J. Capturing disease severity in LIS1-lissencephaly reveals proteostasis dysregulation in patient-derived forebrain organoids.Nat Commun. 2025 16(1):9091.
  2. Wilkens R, Hoffrichter A, Kleinsimlinghaus K, Bohl B, Haag C, Lehmann N, Schmidt M, Munoz Perez-Vico E, Wangemann J, Rehder K, Horschitz S, Köhr G, Ladewig J, Koch P. Diverse maturity-dependent and complementary anti-apoptotic brakes safeguard human iPSC-derived neurons from cell death.Cell Death Dis. 2022 13(10):887.
  3. Jabali A, Hoffrichter A, Uzquiano A, Marsoner F, Wilkens R, Siekmann M, Bohl B, Rossetti AC, Horschitz S, Koch P, Francis F, Ladewig J. Human cerebral organoids reveal progenitor pathology in EML1-linked cortical malformation.EMBO Rep. 2022 23(5):e54027. Epub 2022 Mar 15.

Zentralinstitut für Seelische Gesundheit (ZI) - https://www.zi-mannheim.de