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Publications: Institute of Psychopharmacology

Akan M, Skorodumov I, Meinhardt M, Canbeyli R, Unal G. A shea butter-based ketamine ointment: The antidepressant effects of transdermal ketamine in rats. Behav Brain Res. 2023 452:114594. Epub 2023 Jul 23.
Biria M, Banca P, Healy MP, Keser E, Sawiak SJ, Rodgers CT, Rua C, de Souza AMFLP, Marzuki AA, Sule A, Ersche KD, Robbins TW. Cortical glutamate and GABA are related to compulsive behaviour in individuals with obsessive compulsive disorder and healthy controls. Nat Commun. 2023 14(1):3324.
Buchborn T, Kettner HS, Kärtner L, Meinhardt M. The ego in psychedelic drug action - ego defenses, ego boundaries, and the therapeutic role of regression. Front Neurosci. 2023 17:1232459.
Chavanne AV, Paillère Martinot ML, Penttilä J, Grimmer Y, Conrod P, Stringaris A, van Noort B, Isensee C, Becker A, Banaschewski T, Bokde AL, Desrivieres S, Flor H, Grigis A, Garavan H, Gowland P, Heinz A, Brühl R, Nees F, Papadopoulos Orfanos D, Paus T, Poustka L, Hohmann S, Millenet S, Fröhner JH, Smolka MN, Walter H, Whelan R, Schumann G, Martinot JL, Artiges E, IMAGEN consortium . Anxiety onset in adolescents: a machine-learning prediction. Mol Psychiatry. 2023 28(2):639-646. Epub 2022 Dec 8.
Domanegg K, Sommer WH, Meinhardt M. Psychedelic Targeting of Metabotropic Glutamate Receptor 2 and Its Implications for the Treatment of Alcoholism. Cells. 2023 12(6)
Foo J, Skorodumov I, Spanagel R, Meinhardt M. Sex- and age-specific effects on the development of addiction and compulsive-like drinking in rats. Biol Sex Differ. 2023 14(1):44.
Friske MM, Giannone F, Senger M, Seitz R, Hansson AC, Spanagel R. Chronic alcohol intake regulates expression of SARS-CoV2 infection-relevant genes in an organ-specific manner. Alcohol Clin Exp Res. 2023 47(1):76-86. Epub 2023 Feb 12.
Friske MM, Spanagel R. Chronic alcohol consumption and COVID-19 infection risk: A narrative review. Alcohol Clin Exp Res. 2023 47(4):629-639. Epub 2023 Feb 27.
Gerhardt S, Berhe O, Mößnang C, Horning M, Kiefer F, Tost H, Vollstädt-Klein S. Lack of amygdala habituation to negative emotional faces in alcohol use disorder and the relation to adverse childhood experiences. Addict Biol. 2023 28(1):e13251.
Graf A, Murray SH, Eltahir A, Patel S, Hansson AC, Spanagel R, McCormick CM. Acute and long-term sex-dependent effects of social instability stress on anxiety-like and social behaviours in Wistar rats. Behav Brain Res. 2023 438:114180. Epub 2022 Oct 28.
Guiraud J, Addolorato G, Aubin HJ, Bachelot S, Batel P, de Bejczy A, Benyamina A, Caputo F, Couderc M, Dematteis M, Goudriaan AE, Gual A, Lecoustey S, Lesch OM, Maremmani I, Nutt DJ, Paille F, Perney P, Rehm J, Rolland B, Scherrer B, Simon N, Söderpalm B, Somaini L, Sommer WH, Spanagel R, Walter H, van den Brink W. Sodium Oxybate for Alcohol Dependence: A Network Meta-Regression Analysis Considering Population Severity at Baseline and Treatment Duration. Alcohol Alcohol. 2023 58(2):125-133. Epub 2023 Jan 6.
Halfmann M, Wetzel L, Castioni N, Kiefer F, König S, Schmieder A, Koopmann A. The impact of COVID-19 pandemic on mental burden and quality of life in medical students - results of an online survey. GMS J Med Educ. 2023 40(2):Doc21.
Hoffmann S, Gerhardt S, Koopmann A, Bach P, Sommer WH, Kiefer F, Mazza M, Lenz B. Body mass index interacts with sex to predict readmission in in-patients with alcohol use disorder. Addict Biol. 2023 28(1):e13239.
Hornoiu IL, Lee AM, Tan H, Nakovics H, Bach P, Mann K, Kiefer F, Sommer WH, Vollstädt-Klein S. The Role of Unawareness, Volition, and Neural Hyperconnectivity in Alcohol Use Disorder: A Functional Magnetic Resonance Imaging Study. Biol Psychiatry Cogn Neurosci Neuroimaging. 2023 8(6):660-671. Epub 2022 Dec 22.
Iwasaki M, Lefevre A, Althammer F, Clauss Creusot E, Łąpieś O, Petitjean H, Hilfiger L, Kerspern D, Melchior M, Küppers S, Krabichler Q, Patwell R, Kania A, Gruber T, Kirchner MK, Wimmer M, Fröhlich H, Dötsch L, Schimmer J, Herpertz SC, Ditzen B, Schaaf CP, Schönig K, Bartsch D, Gugula A, Trenk A, Blasiak A, Stern JE, Darbon P, Grinevich V, Charlet A. An analgesic pathway from parvocellular oxytocin neurons to the periaqueductal gray in rats. Nat Commun. 2023 14(1):1066.
Kalinichenko LS, Mühle C, Jia T, Anderheiden F, Datz M, Eberle AL, Eulenburg V, Granzow J, Hofer M, Hohenschild J, Huber SE, Kämpf S, Kogias G, Lacatusu L, Lugmair C, Taku SM, Meixner D, Sembritzki NK, Praetner M, Rhein C, Sauer C, Scholz J, Ulrich F, Valenta F, Weigand E, Werner M, Tay N, Mc Veigh CJ, Haase J, Wang AL, Abdel-Hafiz L, Huston JP, Smaga I, Frankowska M, Filip M, Lourdusamy A, Kirchner P, Ekici AB, Marx LM, Suresh NP, Frischknecht R, Fejtova A, Saied EM, Arenz C, Bozec A, Wank I, Kreitz S, Hess A, Bäuerle T, Ledesma MD, Mitroi DN, Miranda AM, Oliveira TG, Lenz B, Schumann G, Kornhuber J, Müller CP. Adult alcohol drinking and emotional tone are mediated by neutral sphingomyelinase during development in males. Cereb Cortex. 2023 33(3):844-864. Epub 2022 Mar 16.
Kalinichenko LS, Smaga I, Filip M, Lenz B, Kornhuber J, Müller CP. Sex-specific Effects of Different Types of Prenatal Stress on Foetal Testosterone Levels and NMDA Expression in Mice. Behav Brain Res. 2023 439:114225. Epub 2022 Nov 23.
Kind L, Luttenberger K, Leßmann V, Dorscht L, Mühle C, Müller CP, Siegmann EM, Schneider S, Kornhuber J. New ways to cope with depression-study protocol for a randomized controlled mixed methods trial of bouldering psychotherapy (BPT) and mental model therapy (MMT). Trials. 2023 24(1):602.
Koopmann A, Wetzel L, Hoffmann S, Hillemacher T, Georgiadou E, Kiefer F. Auswirkungen des Lockdowns im Frühjahr 2020 während der SARS-CoV-2-Pandemie auf das Alkoholkonsumverhalten bei Raucherinnen und Rauchern. Sucht. 2023 69(6):263-273.
Li Y, Vogel C, Kalinichenko LS, Hübner H, Weikert D, Schaefer N, Gmeiner P, Villmann C, Pischetsrieder M, Müller CP. The beer component hordenine inhibits alcohol addiction-associated behaviours in mice. Addict Biol. 2023 28(8):e13305.
Meinhardt M, Sommer WH. Schrooms against booze: Potential of mycotherapy for the treatment of AUD. Neuropsychopharmacology. 2023 48(1):211-212. Epub 2022 Sep 8.
Musial MPM, Beck A, Rosenthal A, Charlet K, Bach P, Kiefer F, Vollstädt-Klein S, Walter H, Heinz A, Rothkirch M. Reward Processing in Alcohol-Dependent Patients and First-Degree Relatives: Functional Brain Activity During Anticipation of Monetary Gains and Losses. Biol Psychiatry. 2023 93(6):546-557. Epub 2022 May 27.
Müller CP, Schumann G, Rehm J, Kornhuber J, Lenz B. Self-management with alcohol over lifespan: psychological mechanisms, neurobiological underpinnings, and risk assessment. Mol Psychiatry. 2023 28(7):2683-2696. Epub 2023 Apr 28.
Nakovics H, Hoffmann S, Koopmann A, Bach P, Abel M, Sommer WH, Kiefer F, Weinland C, von Zimmermann C, Siegmann EM, Kornhuber J, Mühle C, Schneider U, Toto S, Hillemacher T, Frieling H, Bleich S, Eberlein CK, Lenz B. Psychometric properties of the German Penn Alcohol Craving Scale. Alcohol Alcohol. 2023 59(6):637-344. Epub 2023 Jul 26.
Nguyen T, Zillich L, Cetin M, Hall ASM, Foo JC, Sirignano L, Frank J, Send T, Gilles M, Rietschel M, Deuschle M, Witt SH, Streit F. Psychological, endocrine and polygenic predictors of emotional well-being during the COVID-19 pandemic in a longitudinal birth cohort. Stress. 2023 26(1):2234060. Epub 2023 Nov.
Pagano R, Salamian A, Zielinski J, Beroun A, Nalberczak-Skóra M, Skonieczna E, Cały A, Tay N, Banaschewski T, Desrivieres S, Grigis A, Garavan H, Heinz A, Brühl R, Martinot JL, Martinot MP, Artiges E, Nees F, Orfanos DP, Poustka L, Hohmann S, Fröhner JH, Smolka MN, Vaidya N, Walter H, Whelan R, IMAGEN consortium , Kalita K, Bito H, Müller CP, Schumann G, Okuno H, Radwanska K. Arc controls alcohol cue relapse by a central amygdala mechanism. Mol Psychiatry. 2023 28(2):733-745. Epub 2022 Nov 10.
Pérez-Cervera L, De Santis S, Marcos E, Ghorbanzad-Ghaziany Z, Trouvé-Carpena A, Selim MK, Perez-Ramirez U, Pfarr S, Bach P, Halli P, Kiefer F, Moratal D, Kirsch P, Sommer WH, Canals S. Alcohol-induced damage to the fimbria/fornix reduces hippocampal-prefrontal cortex connection during early abstinence. Acta Neuropathol Commun. 2023 11(1):101.
Reinwald J, Schmitz C, Skorodumov I, Kuchar M, Weber-Fahr W, Spanagel R, Meinhardt M. Psilocybin-induced default mode network hypoconnectivity is blunted in alcohol-dependent rats. Transl Psychiatry. 2023 13(1):392.
Riegler A, Bumb JM, Wisch C, Schuster R, Reinhard I, Hoffmann S, Frischknecht U, Enning F, Schmahl C, Kiefer F, Koopmann A. Does the Augmentation of Trauma Informed Hatha Yoga Increase the Effect of Dialectical Behavior Therapy for Substance Use Disorders on Psychopathological Strain of Patients with Borderline Personality Disorder and Comorbid Substance Use Disorder? Results . Eur Addict Res. 2023 29(1):1-8. Epub 2022 Oct 10.
Ruiz-España S, Ortiz-Ramón R, Perez-Ramirez U, Díaz-Parra A, Ciccocioppo R, Bach P, Vollstädt-Klein S, Kiefer F, Sommer WH, Canals S, Moratal D. MRI texture-based radiomics analysis for the identification of altered functional networks in alcoholic patients and animal models. Comput Med Imaging Graph. 2023 104:102187. Epub 2023 Jan 21.
Spreer M, Grählert X, Klut IM, Al Hamdan F, Sommer WH, Plawecki MH, O'Connor S, Böttcher M, Sauer C, Smolka MN, Zimmermann US. Using naltrexone to validate a human laboratory test system to screen new medications for alcoholism (TESMA)- a randomized clinical trial. Transl Psychiatry. 2023 13(1):113.
Spriggs MJ, Giribaldi B, Lyons T, Rosas FE, Kärtner LS, Buchborn T, Douglass HM, Roseman L, Timmermann C, Erritzoe D, Nutt DJ, Carhart-Harris RL. Body mass index (BMI) does not predict responses to psilocybin. J Psychopharmacol. 2023 37(1):107-116.
Tan H, Gerchen M, Bach P, Lee AM, Hummel O, Sommer W, Kirsch P, Kiefer F, Vollstädt-Klein S. Decoding fMRI alcohol cue reactivity and its association with drinking behaviour. BMJ Ment Health. 2023 26(1)
Tan H, Hubertus S, Thomas S, Lee AM, Gerhardt S, Gerchen M, Sommer WH, Kiefer F, Schad L, Vollstädt-Klein S. Association between iron accumulation in the dorsal striatum and compulsive drinking in alcohol use disorder. Psychopharmacology (Berl). 2023 240(2):249-257. Epub 2022 Dec 29.
Thome J, Pinger M, Durstewitz D, Sommer WH, Kirsch P, Koppe G. Model-based experimental manipulation of probabilistic behavior in interpretable behavioral latent variable models. Front Neurosci. 2023 16:1077735.
Urban MM, Stingl MR, Meinhardt M. Mini-review: The neurobiology of treating substance use disorders with classical psychedelics. Front Neurosci. 2023 17:1156319.
Wang D, Treede RD, Köhr G. Electrophysiological evidence that TRPM3 is a candidate in latent spinal sensitization of chronic low back pain. Neurosci Lett. 2023 816:137509. Epub 2023 Oct 5.
Weber A, Shevchenko Y, Gerhardt S, Hoffmann S, Kiefer F, Vollstädt-Klein S. Effectiveness of Reducing Craving in Alcohol Use Disorder Using a Serious Game (SALIENCE): Randomized Controlled Trial. JMIR Form Res. 2023 7:e42194.
Wetzel L, Halfmann M, Castioni N, Kiefer F, König S, Schmieder A, Koopmann A. The impact of COVID-19 pandemic on mental burden and quality of life in physicians: Results of an online survey. Front Psychiatry. 2023 14:1068715.
Yunusa S, Hassan Z, Müller CP. Mitragynine inhibits hippocampus neuroplasticity and its molecular mechanism. Pharmacol Rep. 2023 75(6):1488-1501.
Zech H, Waltmann M, Lee Y, Reichert M, Bedder RL, Rutledge RB, Deeken F, Wenzel J, Wedemeyer F, Aguilera A, Aslan A, Bach P, Bahr NS, Ebrahimi C, Fischbach PC, Ganz M, Garbusow M, Großkopf CM, Heigert M, Hentschel A, Belanger M, Karl D, Pelz P, Pinger M, Riemerschmid C, Rosenthal A, Steffen J, Strehle J, Weiss F, Wieder G, Wieland A, Zaiser J, Vetter S, Liu S, Goschke T, Walter H, Tost H, Lenz B, Andoh J, Ebner-Priemer U, Rapp MA, Heinz A, Dolan R, Smolka MN, Deserno L, ReCoDe-Consortium . Measuring self-regulation in everyday life: Reliability and validity of smartphone-based experiments in alcohol use disorder. Behav Res Methods. 2023 55(8):4329-4342. Epub 2022 Dec 12.
Zhou R, Foo JC, Nishida A, Ogawa S, Togo F, Sasaki T. Longitudinal relationships of psychotic-like experiences with suicidal ideation and self-harm in adolescents. Eur Child Adolesc Psychiatry. 2023 33(6):1977-1985. Epub 2023 Sep 23.


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