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Publications: Institute of Psychopharmacology

Bernabeu T, Vollstädt-Klein S, Kiefer F, Rolland B. Structural brain effects of alcohol use patterns in alcohol use disorder: A systematic review and Meta-analysis. Prog Neuropsychopharmacol Biol Psychiatry. 2026 146:111684.
Boroumand Jazi RB, Hoffmann S, Reinhard I, Bach P, Sommer WH, Kundlacz M, Müller CP, Reichl M, Tan H, Wenger LP, Beck A, Vollstädt-Klein S, Kiefer F, Mühle C, Gerhardt S, Lenz B. Dihydrotestosterone and Finasteride Effects on Alcohol Cue-Elicited Brain Activity in Males With Heavy Episodic Drinking. Addict Biol. 2026 31(2):e70123.
Ciccocioppo E, Massetti S, Meinhardt M, Fumagalli F, Romualdi P, Roberto M, Spanagel R, Ciccocioppo R, Domi E. (R)-Ketamine reduces alcohol intake and alcohol seeking induced by reconsolidation of alcohol-related memories in female Marchigian Sardinian alcohol-preferring rats. Psychopharmacology (Berl). 2026 243(5):1171-1183. Epub 2025 Nov 15.
Geissler CJ, Lim TV, Görne HA, Krenkel S, Büchel C, Ersche KD. Increased Avoidance Learning in Chronic Opioid Users. JAMA Psychiatry. 2026 83(3):292-297. Epub 2025 Nov 6.
Hoertel N, Mühle C, Müller CP, Chaieb H, Scheer V, Fayad M, Sánchez-Rico M, Limosin F, Kornhuber J. The role of sphingolipids in major depressive disorder and associated cognitive impairment: interactions with monoaminergic signaling, neuroinflammation, and neurogenesis. Mol Psychiatry. 2026 May 13. [Epub ahead of print]
Hoffman PL, de Guglielmo G, Vengeliene V, Kunze W, Lebonville CL, Swinny JD, Roberts AJ, George O, Neufeld KM, Dunbar A, Saba LM, Ma R, Vendruscolo LF, Becker HC, Spanagel R, Tabakoff B. Engaging Gut-to-Brain Signalling to Treat Alcohol Use Disorder. Addict Biol. 2026 31(3):e70144.
Kalinichenko LS, Krenbauer M, Isert J, Kamlah M, Tanzer T, Rödel H, Müller T, Annamneedi A, Akdaş EY, Eulenburg V, Lenz B, Gundelfinger ED, Kornhuber J, Fejtova A, Müller CP. Dissociating role of Bassoon in glutamatergic and dopaminergic neurons in alcohol-related behaviour and affective state in mice. Br J Pharmacol. 2026 183(11):3111-3128. Epub 2026 Feb 26.
Kalinichenko LS, Zoicas I, Mühle C, Kornhuber J, Müller CA. Sphingolipids in Emotional Well-Being. J Neurochem. 2026 170(2):e70379.
Meinhardt M, Skorodumov I, Walter F, Akan M, Buchborn T, Prieult YL, Urban MM, Spanagel R, von Ammon L, Hopf C, Kalinichenko L, Mueller C, Winter C, Hadar R, Gül AZ, Massuda B, Hildebrandt M, Domi E, Keshishian A, Ciccocioppo R, Sames D, Havel V, Woods L, Beeson A. Oxa-noribogaine reduces alcohol drinking through aversion learning and by altering glutamatergic activity in the mPFC. Res Sq. 2026
Müller CP. Commentary on Zacher et al.: How cocaine memories may drive craving and drug instrumentalization. Addiction. 2026 Jun 25. [Epub ahead of print]
Pfisterer M, Teetzmann A, Vetter S, Baeßler J, Schreckenberger L, Zaiser J, Stenger M, Bach P. CBD attenuates amygdala response to negative emotional stimuli in individuals with alcohol use disorder - a randomized controlled trial. Psychopharmacology (Berl). 2026 243(3):553-563. Epub 2025 Aug 29.
Salamian A, Pagano R, Skonieczna E, Kalinichenko LS, Puchalska M, Yiğit Ünlü G, Gajewska-Woźniak O, Kruashvili L, Grochowicz M, Wojtas B, Gielniewski B, Harda Z, Cały A, Mühle C, Lenz B, Kornhuber J, Lourdusamy A, Havekes R, Abel T, Müller CP, Radwanska K. Hippocampal Cofilin and CFL1 gene variants are linked to Alcohol Use Disorder phenotypes. Mol Psychiatry. 2026 31(3):1216-1230. Epub 2025 Sep 11.
Schimmer S, Kania A, Lefevre A, Afordakos K, Wang KY, Lebedeva J, Rozov A, Raftogianni A, Tiwari R, Netser S, Zovko A, Shaheen H, Schimmer J, Patwell R, Denis C, Grelot V, Petitjean H, Geng L, Hefter D, Boender A, Podpecan Y, Schommer F, Schubert T, Sanetra A, Trenk A, Gugula A, Hurlemann R, Wagner S, Li Y, Althammer F, Blasiak A, Melzer S, Monyer H, Charlet A, Eliava M, Grinevich V. Oxytocin facilitates social behavior of female rats via selective modulation of interneurons in the medial prefrontal cortex. Nat Commun. 2026 17(1)
Schmidt M, Hoffrichter A, Davoudi M, Horschitz S, Lau T, Meinhardt M, Spanagel R, Ladewig J, Köhr G, Koch P. Psilocin fosters neuroplasticity in iPSC-derived human cortical neurons. Elife. 2026 14
Spanagel R, Andrade FRT. Kappa opioid receptors mediate aversion-and it matters. Neuropsychopharmacology. 2026 Jun 29. [Epub ahead of print]
Stürzenberger S, Bülow N, Kalinichenko LS, Licha R, Eulenburg V, Dahlmanns M, Müller CP, Zheng F, Alzheimer C. Heavy adolescent drinking makes the adult brain more vulnerable to ethanol by permanently altering the age-dependent interplay between alcohol, GIRK channels and activin. Mol Psychiatry. 2026 31(2):1027-1040.
Türkmen C, Lee AM, Tan H, Kiefer F, Gerhardt S, Vollstädt-Klein S. The association between adverse childhood experiences and inhibitory control in heavy-drinking adults: A functional MRI study. Acta Psychol (Amst). 2026 264:106540. Epub 2026 Mar 4.
Urban MM, Zillich L, Rieser NM, Herdener M, Spanagel R, Vollenweider FX, Preller KH, Meinhardt M. Epigenome-wide association study of psilocybin-induced methylome changes in alcohol use disorder. Transl Psychiatry. 2026 16(1)
Zaiser J, Nitsche J, Hoffmann S, Vetter S, Bahr NS, Grundmann C, Krasniqi S, Arntz F, Strehle J, Marxen M, Vollstädt-Klein S, Rapp MA, Lenz B, Spanagel R, Smolka M, Heinz A, Schwarz E, Kiefer F, Bach P. Investigating Factors Associated With Spontaneous Remission in Individuals With Alcohol Use Disorder-Results From a Multi-Site Longitudinal Cohort Study. Addict Biol. 2026 31(5):e70153.


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