Andlauer TFM, Guzman-Parra J, Streit F, Strohmaier J, Gonzalez MJ, Gil Flores S, Cabaleiro Fabeiro FJ, Del Río Noriega F, Perez FP, Haro González J, Orozco Diaz G, de Diego-Otero Y, Moreno-Küstner B, Auburger G, Degenhardt F, Heilmann-Heimbach S, Herms S, Hoffmann P, Frank J, Foo JC, Treutlein J, Witt S, Cichon S, Kogevinas M, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium , Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium , Rivas F, Mayoral F, Müller-Myhsok B, Forstner AJ, Nöthen MM, Rietschel M. Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders. Mol Psychiatry. 2021 26(4):1286-1298. Epub 2019 Nov 11.
Asan L, Falfán-Melgoza C, Beretta CA, Sack MS, Zheng L, Weber-Fahr W, Kuner T, Knabbe J. Cellular correlates of gray matter volume changes in magnetic resonance morphometry identified by two-photon microscopy. Sci Rep. 2021 11(1):4234.
Bach P, Weil G, Pompili E, Hoffmann S, Hermann D, Vollstädt-Klein S, Kiefer F, Mann KF, Sommer WH. FMRI-based prediction of naltrexone response in alcohol use disorder: a replication study. Eur Arch Psychiatry Clin Neurosci. 2021 271(5):915-927. Epub 2021 Apr 21..
Bertocchi I, Eltokhi A, Rozov A, Chi VN, Jensen V, Bus T, Pawlak V, Serafino M, Sonntag H, Yang B, Burnashev N, Li SB, Obenhaus HA, Both M, Niewoehner B, Single FN, Briese M, Boerner T, Gass P, Rawlins JNP, Köhr G, Bannerman DM, Sprengel R. Voltage-independent GluN2A-type NMDA receptor Ca signaling promotes audiogenic seizures, attentional and cognitive deficits in mice. Commun Biol. 2021 4(1):59.
Bertocchi I, Eltokhi A, Rozov A, Chi VN, Jensen V, Bus T, Pawlak V, Serafino M, Sonntag H, Yang B, Burnashev N, Li SB, Obenhaus HA, Both M, Niewoehner B, Single FN, Briese M, Boerner T, Gass P, Rawlins JNP, Köhr G, Bannerman DM, Sprengel R. Author Correction: Voltage-independent GluN2A-type NMDA receptor Ca signaling promotes audiogenic seizures, attentional and cognitive deficits in mice. Commun Biol. 2021 4(1):187.
Bespalov A, Bernard R, Gilis A, Gerlach B, Guillén J, Castagné V, Lefevre IA, Ducrey F, Monk L, Bongiovanni S, Altevogt B, Arroyo-Araujo M, Bikovski L, de Bruin N, Castaños-Vélez E, Dityatev A, Emmerich CH, Fares R, Ferland-Beckham C, Froger-Colléaux C, Gailus-Durner V, Holter SM, Hofmann MC, Kabitzke P, Kas MJ, Kurreck C, Moser P, Pietraszek M, Popik P, Potschka H, Prado Montes de Oca E, Restivo L, Riedel G, Ritskes-Hoitinga M, Samardzic J, Schunn M, Stöger C, Võikar V, Vollert J, Wever KE, Wuyts K, MacLeod MR, Dirnagl U, Steckler T. Introduction to the EQIPD quality system. Elife. 2021 10
Briševac D, Scholz R, Du D, Elagabani MN, Köhr G, Kornau HC. The small GTPase Arf6 is dysregulated in a mouse model for fragile X syndrome. J Neurochem. 2021 157(3):666-683. Epub 2020 Oct 30.
Emmerich CH, Gamboa LM, Hofmann MCJ, Bonin-Andresen M, Arbach O, Schendel P, Gerlach B, Hempel K, Bespalov A, Dirnagl U, Parnham MJ. Improving target assessment in biomedical research: the GOT-IT recommendations. Nat Rev Drug Discov. 2021 20(1):64-81.
Graf A, Vengeliene V, Skorodumov I, Meinhardt M, Hansson AC, Spanagel R. Adverse social experiences in adolescent rats result in persistent sex-dependent effects on alcohol-seeking behavior. Alcohol Clin Exp Res. 2021 45(7):1468-1478.
Guiraud J, Addolorato G, Aubin HJ, Batel P, de Bejczy A, Caputo F, Goudriaan AE, Gual A, Lesch O, Maremmani I, Perney P, Poulnais R, Raffaillac Q, Söderpalm B, Spanagel R, Walter H, van den Brink W, SMO032 study group . Treating alcohol dependence with an abuse and misuse deterrent formulation of sodium oxybate: Results of a randomised, double-blind, placebo-controlled study. Eur Neuropsychopharmacol. 2021 52:18-30. Epub 2021 Jul 5.
Guzman-Parra J, Streit F, Forstner AJ, Strohmaier J, Gonzalez MJ, Gil Flores S, Cabaleiro Fabeiro FJ, Del Río Noriega F, Perez Perez F, Haro González J, Orozco Diaz G, de Diego-Otero Y, Moreno-Küstner B, Auburger G, Degenhardt F, Heilmann-Heimbach S, Herms S, Hoffmann P, Frank J, Foo JC, Sirignano L, Witt S, Cichon S, Rivas F, Mayoral F, Nöthen MM, Andlauer TFM, Rietschel M. Clinical and genetic differences between bipolar disorder type 1 and 2 in multiplex families. Transl Psychiatry. 2021 11(1):31.
Hansson AC, Spanagel R. No changes in the oxytocin system in alcohol-dependent female rodents and humans: Towards a sex-specific psychopharmacology in alcoholism. Addict Biol. 2021 26(2):e12945. Epub 2020 Aug 5.
Hasanpour MH, Mitricheva E, Logothetis N, Noori HR. Intensive longitudinal characterization of multidimensional biobehavioral dynamics in laboratory rats. Cell Rep. 2021 35(2):108987.
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Johnstone AL, Andrade NS, Barbier E, Khomtchouk BB, Rienas CA, Lowe K, Van Booven DJ, Domi E, Esanov R, Vilca S, Tapocik JD, Rodriguez K, Maryanski D, Keogh MC, Meinhardt M, Sommer WH, Heilig M, Zeier Z, Wahlestedt C. Dysregulation of the histone demethylase KDM6B in alcohol dependence is associated with epigenetic regulation of inflammatory signaling pathways. Addict Biol. 2021 26(1):e12816. Epub 2019 Aug 1.
Kärtner L, Steinborn MB, Kettner H, Spriggs MJ, Roseman L, Buchborn T, Balaet M, Timmermann C, Erritzoe D, Carhart-Harris RL. Positive expectations predict improved mental-health outcomes linked to psychedelic microdosing. Sci Rep. 2021 11(1):1941.
Olevska A, Spanagel R, Bernardi R. Impaired contextual fear conditioning in RasGRF2 mutant mice is likely Ras-ERK-dependent. Neurobiol Learn Mem. 2021 181:107435. Epub 2021 Apr 6..
Pallarés V, Dudek M, Moreno A, Perez-Ramirez U, Moratal D, Haaranen M, Ciccocioppo R, Sommer WH, Canals S, Hyytiä P. Neuroimaging reveals functionally distinct neuronal networks associated with high-level alcohol consumption in two genetic rat models. Behav Pharmacol. 2021 32(2/3):229-238. Epub 2020 Sep 10.
Pohorala V, Enkel T, Bartsch D, Spanagel R, Bernardi R. Sign- and goal-tracking score does not correlate with addiction-like behavior following prolonged cocaine self-administration. Psychopharmacology (Berl). 2021 238(8):2335-2346. Epub 2021 May 5..
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Pohorala V, Enkel T, Bartsch D, Spanagel R, Bernardi R. Comment on Flagel et al.: Sign-tracking as a predictor of addiction vulnerability. Psychopharmacology (Berl). 2021 238(9):2665-2666. Epub 2021 Jul 29.
Restivo L, Gerlach B, Tsoory M, Bikovski L, Badurek S, Pitzer C, Kos-Braun IC, Mausset-Bonnefont AM, Ward J, Schunn M, Noldus LP, Bespalov A, Võikar V. Towards best practices in research: Role of academic core facilities. EMBO Rep. 2021 22(12):e53824.
Russo E, Ma T, Spanagel R, Durstewitz D, Toutounji H, Köhr G. Coordinated prefrontal state transition leads extinction of reward-seeking behaviors. J Neurosci. 2021 41(11):2406-2419. Epub 2021 Feb 1.
Sack MS, Zheng L, Gass N, Ende G, Sartorius A, Weber-Fahr W. Interactive tool to create adjustable anatomical atlases for mouse brain imaging. MAGMA. 2021 34(2):183-187. Epub 2020 Jul 21.
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Schuster R, Winkler M, Koopmann A, Bach P, Hoffmann S, Reinhard I, Spanagel R, Bumb JM, Sommer WH, Kiefer F. Calcium Carbonate Attenuates Withdrawal and Reduces Craving: A Randomized Controlled Trial in Alcohol-Dependent Patients. Eur Addict Res. 2021 27(5):332-340. Epub 2021 Feb 10.
Serrano A, Vadas E, Ferrer B, Bilbao A, Granado N, Suárez J, Pavón FJ, Moratalla R, Rodríguez de Fonseca F. Genetic deletion of dopamine D1 receptors increases the sensitivity to cannabinoid CB1 receptor antagonist-precipitated withdrawal when compared with wild-type littermates: studies in female mice repeatedly exposed to the Spice cannabinoid HU-210. Psychopharmacology (Berl). 2021 238(2):551-557.
Spanagel R, Bilbao A. Approved cannabinoids for medical purposes - Comparative systematic review and meta-analysis for sleep and appetite. Neuropharmacology. 2021 :108680. Epub 2021 Jun 25.
Velo Escarcena L, Neufeld M, Rietschel M, Spanagel R, Scholz H. ERR and dPECR Suggest a Link Between Neuroprotection and the Regulation of Ethanol Consumption Preference. Front Psychiatry. 2021 12:655816.
Wandres M, Pfarr S, Molnár B, Schöllkopf U, Ercsey-Ravasz M, Sommer WH, Körber C. Alcohol and sweet reward are encoded by distinct meta-ensembles. Neuropharmacology. 2021 195:108496. Epub 2021 Feb 11.
Wei S, Hertle S, Spanagel R, Bilbao A. Female mice are more prone to develop an addictive-like phenotype for sugar consumption. Sci Rep. 2021 11(1):7364.
Wei S, Hertle S, Spanagel R, Bilbao A. NMDA receptors in accumbal D1 neurons influence chronic sugar consumption and relapse. eNeuro. 2021 8(3):0029. Epub ahead of print 2021 Apr 27.