Ryan Patwell
About me:
I joined the lab of Dr. Grinevich as a post-doctoral researcher in the fall of 2021 after completing my PhD in Neuroscience. I am interested in understanding the reinforcing potential of central oxytocin signaling as it relates to both social and non-social rewards. To achieve this goal I will be using a variety of techniques including operant self-administration, optogenetics, and calcium imaging to characterize and manipulate the central oxytocin system in-vivo.
Ryan holds a B.Sc. in Biological Sciences and a PhD in Neuroscience. He currently works as a postdoc in our team.
Expertise:
| Operant conditioning | Stereotactic Injections |
| Molecular neuroscience | Epigenetic assays |
Selected publications
- Patwell R, Yang H, Pandey SC, Glover EJ. An operant paradigm that discriminates between appetitive and consummatory behaviors reveals distinct behavioral phenotypes in commonly used rat strains.Neuropharmacology. 2021 201, 108836. doi: 10.1016/j.neuropharm.2021.108836. PMID: 34648771
- Dulman RS, Auta J, Wandling GM, Patwell R, Zhang H, Pandey SC. Persistence of cerebellar ataxia during chronic ethanol exposure is associated with epigenetic up-regulation of Fmr1 gene expression in rat cerebellum.Alcohol Clin Exp Res. 2021 Oct;45(10):2006-2016. doi: 10.1111/acer.14691. PMID: 34453331.
- Bondoc JMG, Gutka HJ, Almutari MM, Patwell R, Rutter MW, Wolf NM, Samudrala R, Mehboob S, Movahedzadeh F. Rv0100, a proposed acyl carrier protein in Mycobacterium tuberculosis: expression, purification and crystallization. Acta Crystallogr F Struct Biol Commun. 2019. doi: 10.1107/S2053230X19012652. PMID: 31584013.
- Fitzgerald JM, MacNamara A, DiGangi JA, Kennedy AE, Rabinak CA, Patwell R, Greenstein JE, Proescher E, Rauch S, Hajcak G, Phan KL. (2016); An electrocortical investigation of voluntary emotion regulation in combat-related posttraumatic stress disorder.Psychiatry Research: Neuroimaging. doi: 10.1016/j.pscychresns.2015.12.001. PMID: 26922156.
Zentralinstitut für Seelische Gesundheit (ZI) - https://www.zi-mannheim.de