field magnetic strength for rats is desired to investigate Gln/Glu ratio changes in the equivalent brain region with the ability to achieve reliable spectra quantification for Gln. We aim to validate that [...] motivational value associated with primary punishment in humans and to reveal a new successful target for DBS for patients with therapy-refractory depression [5-9]. Abnormal function of the lateral habenula has [...] Affective scores were significantly lower than sensory scores for all modalities, including the incision. In women, affective scores were not different for blade, laser and incision stimuli. In a second step, a
pathway to modulate brain activity by neuropeptides (a.k.a. non-synaptic axonal release) essential for adaptive behaviors (social behavior, feeding, pain, and fear) altering the 50-year dogma of passive [...] touch-dependent communication in the case of gentle, non-nociceptive stimuli Glial cells as novel target for neuropeptides which improve emotional valence to resist threat both independently and in conjunction [...] paraventricular (PVN) and supraoptic nuclei (SON) of the Hypothalamus, a structure which accounts for less than 1% of the brain's weight, yet is crucial to every individuals survival. Oxytocin modulates
Europäische Union : Part of EURAS – EUropean network for neurodevelopmental RASopathies [HORIZON-HLTH-2022-DISEASE-06-04: Development of new effective therapies for rare diseases]. Ehrenreich H, Bansal V. DFG -
2015),making this model particularly pertinent for understanding the mechanisms of rescue of OT and for optimizing OT-based therapeutic strategies for this neurodevelopmental disorder. The aim of this [...] -related social isolation as a risk factor for psychiatric disorders. Moreover, even perceived social isolation, termed “loneliness”, increases the risk for coronary heart disease, stroke, depression, [...] c tool for individuals suffering from loneliness (WP5) and characterize the effects of touch treatment on oxytocin levels and brain function. This set of experiments will lay the foundation for a new theory
Senior Researcher Dr. Eduard Maier Group Leader Research Group for Neurobiology of Maternal Care Dr. Shimpei Ishiyama Group Leader Research Group for Neurobiology of Positive Emotions Dr. Quirin Krabichler
As core data acquisition site for the Longitudinal European Autism Project (LEAP), CIMH will reassess the local participants for the LEAP wave 3. CIMH will be responsible for the core analysis of the LEAP [...] prescribed medication for ADHD children; it is also increasingly used in ADHD adults. In 2007, the European Commission requested a referral to the Committee for Medicinal Products for Human Use (CHMP) under [...] integrates clinical data sets for ‘addictive’ (ADHD high risk for substance use), ‘anxious’ (OCD) and ‘stereotypical’ (ASD) compulsive behaviors with highly predictive animal models for new pharmacotherapy. In
evidence that after traumatic experience acute memories for these events are repeatedly reactivated for a certain amount of time which allows for the incorporation of new information into trauma related [...] (HR, EMG) and its neural correlates (fMRI). Work schedule: For this project, we will collect data from 60 female patients with BPD (age 18-45). For participating in study 2, we will recruit additionally a [...] expression of social signals; the adjustment of social behavior to social context and its consequences for the sense of belonging). We hypothesize, that basal affiliative processes such as behavioral matching
neuronal ensemble and therefore a sequence of activated neuronal ensembles (meta-ensemble) encodes for the entire behavioral sequence of this reward seeking task. We aim to study the cross-talk of these [...] the molecular mechanism underlying this long-term up-regulation is unknown. Here, we propose a role for dopamine (DA) in the progressive recruitment of CRH signaling during the transition into alcohol dependence [...] rich neuronal populations - the intercalating cell masses (ICM) - with important gating functions for intra-amygdala signal flow. We hypothesize that within these cells D1/CRHR1 receptor interactions play
As core data acquisition site for the Longitudinal European Autism Project (LEAP), CIMH will reassess the local participants for the LEAP wave 3. CIMH will be responsible for the core analysis of the LEAP [...] prescribed medication for ADHD children; it is also increasingly used in ADHD adults. In 2007, the European Commission requested a referral to the Committee for Medicinal Products for Human Use (CHMP) under [...] integrates clinical data sets for ‘addictive’ (ADHD high risk for substance use), ‘anxious’ (OCD) and ‘stereotypical’ (ASD) compulsive behaviors with highly predictive animal models for new pharmacotherapy. In
pulse sequence for BOLD sensitive functional imaging, for diffusion weighted imaging and for structural T1 weighed imaging. In addition each site will implement the agreed battery of tasks for fMRI scanning [...] As core data acquisition site for the Longitudinal European Autism Project (LEAP), CIMH will reassess the local participants for the LEAP wave 3. CIMH will be responsible for the core analysis of the LEAP [...] prescribed medication for ADHD children; it is also increasingly used in ADHD adults. In 2007, the European Commission requested a referral to the Committee for Medicinal Products for Human Use (CHMP) under
