molecular mechanism of altered executive functions and increased relapses in alcohol dependence have been investigated. The research focuses on the role of the metabotropic glutamate receptor 2 (mGluR2). [...] -glutamate and regulates its release in various brain areas. In their current work, which has now been published in the journal Science Advances , the research team shows a causal link between a reduced [...] rodents and an impaired executive control as well as craving for alcohol. mGluR2 activation has thus been identified as a potential therapeutic mechanism in alcohol dependence. Psilocybin restores the production
cells have already been linked to the development of autism. Central role of the protein MYT1L Moritz Mall from the Hector Institute for Translational Brain Research (HITBR) has long been researching the [...] pathways that programme a cell towards muscle or connective tissue, for example. Mutations in MYT1L have been found in some patients with neurological diseases, such as schizophrenia and epilepsy, but also in [...] To do this, they genetically switched off MYT1L – both in mice and in human nerve cells that had been derived from reprogrammed stem cells in the laboratory. Thinner cerebral cortex The loss of MYT1L
information with old knowledge, thus transforming it. Despite enormous progress, this finding has not yet been used to improve mental health, although sleep and memory problems contribute significantly to suffering [...] knowledge to intervene in processing of maladadptive memory during sleep,” says Gordon Feld, who has been using the Emmy Noether funding from the German Research Foundation (DFG) at the CIMH to investigate [...] and memory research has made considerable progress over the past two decades, but this has largely been achieved with the help of relatively simple learning tasks. A decisive innovation in the funded project
Dr. Gordon Feld , head of the Psychology and Neurobiology of Sleep and Memory research group , has been awarded the Supervisor Prize of the German Society for Psychophysiology and its Application (DGPA) [...] Sibel Nayman , research associate in the Research Group Longitudinal and Intervention Research , has been awarded the 2024 Advancement Award for Young Scientists in Clinical Psychology and Psychotherapy. [...] (DGPs). The prize was awarded for work on premenstrual dysphoric disorder (PMDS), a disorder that has been little researched to date but is increasingly becoming the focus of scientific attention. IMMERSE
translational development of pharmacotherapies for patients with alcohol addiction. Prof. Spanagel has been involved in addiction research for over 30 years and is the spokesperson for the Transregio TRR265 [...] factors in order to improve the treatment of patients and strengthen prevention. The Jellinek Prize has been awarded by the Canadian Jellinek Memorial Fund since 1968. It is considered one of the most important
Ms. Borgwedel, you have been Director of Nursing at CIMH since early 2023. Is it your dream job? My dream was always to become a nurse. I have grown into my role of Director of Nursing and I really like [...] paths in further training. The management training program "Professional Leadership in Nursing" has been introduced. Measures like this lead to greater levels of skill, responsibility, and commitment in [...] because it really is varied and I have matured as a person. About Doris Borgwedel Doris Borgwedel has been working in nursing since 1979. After studying as a nurse at a vocational school in the GDR for 14
Dr. Matthias Janta, who has been the Commercial Director of CIMH since 2020, will leave the institute in December to pursue a new professional challenge. The Deputy Commercial Director, Andreas-W. Möller [...] successor is appointed by the CIMH Supervisory Board. Economic Stability Secured Dr. Matthias Janta has been the Commercial Director of CIMH since 2020. During his tenure, CIMH experienced dynamic and successful
labs around the world, he has been able to provide significant stimulus to progress in the field of neuropeptide research internationally. The results of his team have been extensively published in high-impact [...] Andreas Meyer-Lindenberg , Germany, said: “Valery Grinevich’s achievements in neuropeptide research have been critical in advancing the translational pharmacology of mental and metabolic disorders, and have made
II) will include 144 patients with depression aged 25 to 65 years for whom other therapies have not been or are no longer effective. The study treatment consists of two dosing sessions of about six hours [...] who is also head of the Department of Molecular Neuroimaging at the CIMH. Until now, it has often been assumed that mental illnesses are associated with specific molecular dysfunctions that can only be [...] taking a psychedelic, are neither pregnant nor breastfeeding. Contact Recruitment for the study has been completed.
variations, which relate to 308 specific genes, have never before been associated with the disease. The identified genetic variants have been linked to neurons, a type of brain cell, in different regions of [...] a gene – and the disease. This is the first time that new genetic risk factors for depression have been identified across all major world populations. 100 of the newly discovered genetic variations were
