evaluate particularly positive information referenced to themselves as less positive and this has been related to an internal, negative and global attributional style. They feel less included during positive [...] state. During reconsolidation memory can be disrupted, modified or even enhanced. It has recently been demonstrated that oral administration of the β-adrenergic receptor antagonist propranolol during memory
specific for the extensive comorbidity of pain and depression have not been characterized, plasticity in these circuits has not been examined, and the causal status of any neural systems abnormality is unclear [...] longitudinal and multi-modal imaging information at hand has not yet been exploited. After psychiatric neuroimaging research has long been focusing on dedicated regions in the brain (local analysis), the emerging [...] 07 - Neural circuits involved in Phantom Limb Pain . 07/2019-06/2023. Abstract Although there has been much progress in the understanding of phantom limb pain (PLP), we still do not know which factors
both predict rewards and suppress interactions of mPFC and NAc. We will focus on the NAc that has been proposed to serve as a central gateway where converging inputs help to optimize reward outcome. Yet
specific for the extensive comorbidity of pain and depression have not been characterized, plasticity in these circuits has not been examined, and the causal status of any neural systems abnormality is unclear [...] longitudinal and multi-modal imaging information at hand has not yet been exploited. After psychiatric neuroimaging research has long been focusing on dedicated regions in the brain (local analysis), the emerging [...] y stressful. However, scientific evaluation of this assumption is scarce.Specifically, it has not been studied whether models of depression or schizophrenia, to name two most common and severe psychiatric
and depression (S&D) every year, there have been few truly innovative new chemical entities (NCEs) which have made it to the clinic. While there has been a tremendous explosion of new knowledge: dozens [...] pathways identified, numerous imaging findings differentiating patients from controls, yet, it has been hard to take these findings from the bench to the clinic. We think there are three major bottlenecks
chronic alcohol intake leads to neuroinflammation that in turn triggers addictive behaviour. It has been shown that intranasal delivery of mesenchymal stem cell-derived exosomes reduces relapse behaviour
prevalence in Germany, 260 million € annual cost, Schlander, Trott and Schwarz, 2010). It has even been argued that the disorganization of time and the inability to accurately perceive its passage lies
individuals, biobanking, data protection, etc.) have been addressed within the ELSI projects of the Human Genome Project. While standards have been set for certain aspects (e.g. biobanking and data protection) [...] diagnostic boundaries. Background and own previous work: The heritability of bipolar disorder (BD) has been reported to be as high as 80%, while that of major depressive disorder (MDD) ranges between 40 and [...] be analysed throughout the course of the FOR, once a substantial number of the study subjects have been characterized with the PsychChip. The two genes of interest (NCAN, BDNF) will also be analysed in
improvement of patient care. In the heart of Mannheim, the Central Institute of Mental Health has been helping to destigmatize mental illness and integrate patients into society for 50 years. I would like
Momentary Intervention, i.e. a digital intervention. “Many lifestyle and health applications have been developed for smartphones in recent years, but we have hardly any scientific evidence for the safety
