products for the treatment of alcohol addiction provided by the European Medicines Agency (EMA), will adhere to the standards proposed for confirmatory biomedical research (Dirnagl, 2016) for nonclinical [...] emergency situations, and no financing for language services is available for many hospitals, this presents a critical obstacle in providing mental health care for refugees. This consortium will leverage [...] through building a smartphone-based app to be used by the community for logging, therapist communication, and community building, and for monitoring client’s well-being outside the clinic using ecological
field magnetic strength for rats is desired to investigate Gln/Glu ratio changes in the equivalent brain region with the ability to achieve reliable spectra quantification for Gln. We aim to validate that [...] motivational value associated with primary punishment in humans and to reveal a new successful target for DBS for patients with therapy-refractory depression [5-9]. Abnormal function of the lateral habenula has [...] validate the use of fMRI-based paradigms as early and surrogate markers for efficacy; and to combine this with PET approaches for measuring changes in endogenous transmitters – thus providing new methods
Comprehensive European Strategy . 01/2025-12/2029. Abstract Europe should be prepared for a mental health crisis that will last for decades, impacting on long-term health outcomes and economic productivity of our [...] YOUTHreach will evaluate (cost-)effectiveness of 3 existing and accessible innovative interventions for prevention and early intervention of mental ill-health in youth, that have been developed and tested [...] activities will benefit from engagement of and co-creation with young people and their support network for the whole duration of the project and a lasting privacy protected accessible (FAIR) research data
products for the treatment of alcohol addiction provided by the European Medicines Agency (EMA), will adhere to the standards proposed for confirmatory biomedical research (Dirnagl, 2016) for nonclinical [...] biomarkers for allosteric load. Both in humans and in rodents, we will investigate whether early childhood adversity especially in female subjects significantly sensitizes these circuit alterations. For the future [...] represents a tremendous burden for the patient, health care services, and the general society. Current pharmacological treatment approaches have limited effectiveness. Due to the need for more efficacious treatments
As core data acquisition site for the Longitudinal European Autism Project (LEAP), CIMH will reassess the local participants for the LEAP wave 3. CIMH will be responsible for the core analysis of the LEAP [...] integrates clinical data sets for ‘addictive’ (ADHD high risk for substance use), ‘anxious’ (OCD) and ‘stereotypical’ (ASD) compulsive behaviors with highly predictive animal models for new pharmacotherapy. In [...] Sonderfördermaßnahme COVID-19 Forschung: The impact of Covid-19 on mental health: Longitudinal evidence for prädiktive socioenvironmental and neurobehavioral risk and resilience patterns . 07/2020-06/2021. Holz
products for the treatment of alcohol addiction provided by the European Medicines Agency (EMA), will adhere to the standards proposed for confirmatory biomedical research (Dirnagl, 2016) for nonclinical [...] represents a tremendous burden for the patient, health care services, and the general society. Current pharmacological treatment approaches have limited effectiveness. Due to the need for more efficacious treatments [...] bodies, dose determination and finally cost-intensive phase II clinical testing for psilocybin in alcoholics, we propose for the first time with respect to mental disorders a preclinical multi-center placebo
field magnetic strength for rats is desired to investigate Gln/Glu ratio changes in the equivalent brain region with the ability to achieve reliable spectra quantification for Gln. We aim to validate that [...] motivational value associated with primary punishment in humans and to reveal a new successful target for DBS for patients with therapy-refractory depression [5-9]. Abnormal function of the lateral habenula has [...] validate the use of fMRI-based paradigms as early and surrogate markers for efficacy; and to combine this with PET approaches for measuring changes in endogenous transmitters – thus providing new methods
groups of experts in the field, one for automotive and other for avionis, which despite their different bussines models, share the necessity of basic technologies for the validation and verification of [...] genes that are relevant for mood disorders. These will be related to shared biomarkers to define common biological substrates between early life stress and maternal obesity for prevention and treatment [...] traits in both Drosophila (SP9) and in our platform for experimental human studies (SP12) (Juraeva et al., 2015). In collaboration with SP10, GWAS for specific endophenotypes were performed, and we were
provides a physiologically relevant platform for modeling neuropsychiatric disorders and testing therapeutics. The findings will establish a robust foundation for future funding applications, refine organoid [...] Based on these results, in this project we will further validate constructs for this mutation and develop and validate toolkits for three other MECP2 mutation hotspots, namely c.502C> T (p(R168X)), c.763C> [...] experiments will allow us to demonstrate the full potential of gene editing as a therapeutic option for Rett and for other neurodevelopmental disorders currently lacking an effective treatment. Ladewig J. DFG
Abstract Describe forensic psychiatry services as they exist today in 2018 across the European Union. Identifying risk factors for violence in a unique international forensic sample. Testing for the very first [...] development of an IT infrastructure for geographically distributed application for machine learning, and the encoding of mechanistic knowledge in the form of knowledge graphs for downstream application of artificial [...] As core data acquisition site for the Longitudinal European Autism Project (LEAP), CIMH will reassess the local participants for the LEAP wave 3. CIMH will be responsible for the core analysis of the LEAP
