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Ammar Jabali

PhD Student

Abteilung Translationale Hirnforschung

AG Entwicklungs-assoziierte Erkrankungen des Gehirns

E-Mail

Ammar earned his BSc in Biology in Hanover and his MSc in Molecular Biomedicine in Münster. His PhD thesis focuses on modelling and investigating the development of human cortical malformations using iPSC-derived cerebral organoids, in particular the development of subcortical heterotopia induced by mutations in EML1.

While currently his main interest lies on finishing his PhD, he dedicates a part of his lab time to develop models for organoid-glioblastoma interactions and paediatric choroid plexus neoplasms. Whenever possible, a solid amount of his salary is reinvested into music concerts and festivals across most genres and good wine (of course!).

Publikationen in peer-reviewed Zeitschriften seit 2006

TOP 5 Publikationen:

  1. Hausmann D, Hoffmann DC, Venkataramani V, Jung E, Horschitz S, Tetzlaff SK, Jabali A, Hai L, Kessler T, Azoŕin DD, Weil S, Kourtesakis A, Sievers P, Habel A, Breckwoldt MO, Karreman MA, Ratliff M, Messmer JM, Yang Y, Reyhan E, Wendler S, Löb C, Mayer C, Figarella K, Osswald M, Solecki G, Sahm F, Garaschuk O, Kuner T, Koch P, Schlesner M, Wick W, Winkler F. Autonomous rhythmic activity in glioma networks drives brain tumour growth.Nature. 2023 613(7942):179-186. Epub 2022 Dec 14.
  2. Zillich L, Artioli A, Pohorala V, Zillich E, Stertz L, Belschner H, Jabali A, Frank J, Streit F, Avetyan D, Völker MP, Müller S, Hansson AC, Meyer TD, Rietschel M, Ladewig J, Spanagel R, Oliveira AMM, Walss-Bass C, Bernardi R, Koch P, Witt SH. Cell type-specific multi-omics analysis of cocaine use disorder in the human caudate nucleus.Nat Commun. 2025 16(1):3381.
  3. Hai L, Hoffmann DC, Wagener RJ, Azoŕin DD, Hausmann D, Xie R, Huppertz MC, Hiblot J, Sievers P, Heuer S, Ito J, Cebulla G, Kourtesakis A, Kaulen LD, Ratliff M, Mandelbaum H, Jung E, Jabali A, Horschitz S, Ernst KJ, Reibold D, Warnken U, Venkataramani V, Will R, Suvà ML, Herold-Mende C, Sahm F, Winkler F, Schlesner M, Wick W, Kessler T. A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1.Nat Commun. 2024 15(1):968.
  4. Bohl B, Jabali A, Ladewig J, Koch P. Asymmetric Notch activity by differential inheritance of lysosomes in human neural stem cells.Sci Adv. 2022 8(6):eabl5792.
  5. Ho KH, Trapp M, Guida C, Ivanova EL, De Jaime-Soguero A, Jabali A, Thomas C, Salasova A, Bernatík O, Salio C, Horschitz S, Hasselblatt M, Sassoè-Pognetto M, Čajánek L, Ishikawa H, Schroten H, Schwerk C, Acebrón SP, Angel P, Koch P, Patrizi A. Activation of Wnt/β-catenin signaling is critical for the tumorigenesis of choroid plexus.Neuro Oncol. 2025 27(1):106-122.

Zentralinstitut für Seelische Gesundheit (ZI) - https://www.zi-mannheim.de