(SCU-B), that, albeit already implemented in some European countries, is not widespread and has not been sufficiently studied so far, although it seems to be promising for its short-term efficacy (alleviating [...] something substantial about these diseases, we need to diagnose them early, before too many neurons have been lost, and then treat them with drugs that inhibit the destructive process. Such drugs are in development
evaluate particularly positive information referenced to themselves as less positive and this has been related to an internal, negative and global attributional style. They feel less included during positive [...] state. During reconsolidation memory can be disrupted, modified or even enhanced. It has recently been demonstrated that oral administration of the β-adrenergic receptor antagonist propranolol during memory
Skoglund et al., 2019 ) Despite this evidence of heritability, comparatively few genomic studies have been conducted to identify molecular markers linked to BPD, especially when compared to other mental disorders
l skills, these courses have been organized by the students themselves (with help of the board members of the Integrated Graduate Program). In addition, students have been offered specific training courses [...] of the dissertation script after 1 or 2 articles have been accepted (depending on the extent of the work invested) and one additional article has been submitted at the time of the completion of the degree [...] 07 - Neural circuits involved in Phantom Limb Pain . 07/2019-06/2023. Abstract Although there has been much progress in the understanding of phantom limb pain (PLP), we still do not know which factors
l skills, these courses have been organized by the students themselves (with help of the board members of the Integrated Graduate Program). In addition, students have been offered specific training courses [...] of the dissertation script after 1 or 2 articles have been accepted (depending on the extent of the work invested) and one additional article has been submitted at the time of the completion of the degree [...] chronic alcohol intake leads to neuroinflammation that in turn triggers addictive behaviour. It has been shown that intranasal delivery of mesenchymal stem cell-derived exosomes reduces relapse behaviour
reinforcement learning and reward prediction. In particular the phasic firing of DA midbrain neurons has been interpreted as an important learning signal that may drive adaptive processes in DA-innervated target [...] disorders. One of the major DA target areas is the medial prefrontal cortex (mPFC) which itself has been implicated in associative rule learning and extinction. DA is known to modulate long-term-potentiation
and depression (S&D) every year, there have been few truly innovative new chemical entities (NCEs) which have made it to the clinic. While there has been a tremendous explosion of new knowledge: dozens [...] for patients with therapy-refractory depression [5-9]. Abnormal function of the lateral habenula has been directly linked with major depression [10; 11]. We now aim to express genetically engineered receptors [...] future alternative to deep brain stimulation (DBS). Resting state functional connectivity fMRI has been extensively established at our high field animal scanner [20]. After setting up resting state fMRI
are prescribed to first episode schizophrenics. It is worth noting that, where early treatment has been possible, it is associated with greatly improved patient outcomes. Solution: The SchizDX application [...] specific anti-psychotic action was produced in 1950. Since then, numerous new anti-psychotic drugs have been introduced. Most of these drugs are largely equal in efficacy and differ mainly in profile of side [...] of first episode psychosis. To achieve this, a consortium of 18 European Psychiatric Institutes has been formed from which 350 medication naïve patients with first episode psychosis and a diagnosis of s
negative experiences with them. Aversive anticipations, as triggered by social communication, have been shown to reliably activate physiological defense mechanisms. However, very little is known about how
prevalence in Germany, 260 million € annual cost, Schlander, Trott and Schwarz, 2010). It has even been argued that the disorganization of time and the inability to accurately perceive its passage lies [...] have decided to use animals from the “post-dependent model”7 (SP5) to do these experiments. What has been achieved in the first two years is a computational framework for highthroughput characterization of [...] reinforcement learning and reward prediction. In particular the phasic firing of DA midbrain neurons has been interpreted as an important learning signal that may drive adaptive processes in DA-innervated target