schizophrenia have shown that NSS are associated with abnormal cortical and subcortical structure and function. Yet, it still remains unclear whether these findings are associated with neuropathological [...] delineation using active learning. By training supportive machine learning algorithms on the fly that are custom tailored to the respective analysis pipeline used to obtain the tractogram as well as to the [...] catatonia as well as an in-depth understanding of (patho)physiologically-relevant mechanisms that are essential for advancing precision-medicine–informed treatment options for catatonia. DFG - Deutsche

Current treatments are symptomatic but do not stop the underlying disease process. Using biomarkers, we can detect biochemical changes that show when neurons start to die. There are also biochemical tests [...] The current state-of-the-art of the treatment of these symptoms is still unsatisfactory and there are many unmet needs in this area. The major objective of the project will be to assess the effectiveness [...] eness of the proposed intervention will be tested in the prospective study. The expected benefits are socially appreciable: improving quality of life of persons with dementia, lessening caregivers' burden

safety instructions are hypothesized to inhibit fear acquisition and/or to accelerate extinction learning. Attentional processes, psychophysiological responding, and behavioral measures are examined to link [...] can be amazingly persistent – even when the aversive outcomes are never experienced – the implications for a range of anxiety disorders are evident. [...] Attentional processes, psychophysiological responding, behavioral measures and questionnaire data are examined to link face perception and social learning. Taken together, a dimensional transdiagnostic

modifications. If you are interested in working with our data (e.g., summary statistics ) or would like to collaborate on future GWAS , please feel free to get in contact with us . We are always open to expanding [...] and interventions for those affected. We, the International Borderline Genomics Consortium (IBGC) , are a collaborative research network dedicated to uncovering the genetic foundations of BPD. Our work focuses [...] between BPD and loneliness , suggesting that individuals with a genetic predisposition to loneliness are more likely to develop BPD. ( Streit et al., 2022 ; Schulze et al., 2023 ) Our data have also contributed

Investigator Award : Friends or food – are there medial prefrontal circuits dedicated to social decision making?. 11/2017-10/2020. Abstract Rewarding social interactions are fundamental for neurocognitive d [...] development, maintenance of relationships and are impaired in psychiatric disorders. The question how the brain represents social reward value during decision making is fundamental for an understanding [...] use novel decision making tasks in rats together with physiological methods to test whether there are common or distinct neural circuits for social and non-social decision making. It aims to provide novel

progress in the understanding of phantom limb pain (PLP), we still do not know which factors are antecedents and which are consequences of the pain and how central, peripheral and psychological factors interact [...] alcohol abuse are a major medical challenge in chronic pain, especially in female pain patients with adverse childhood experiences. However, it is unknown whether these comorbidities are caused by specific [...] Germany in the 2last years speak languages such as Arabic that are not understood by the resident therapeutic community, interpreters are scarce and not available around the clock or in emergency situations

Oxytocin! Viral Vectors Learn how viruses are utilized for Oxytocin research! Our Team Get to know our team ! Contact Write us an email . Selected ERC synergy grant We are proud to be one of the selected highlights [...] address this challenging multidisciplinary research problem. More information Zum deutschen Artikel We are proud to work together with great teams all over the world Our key collaborators Profs. Philipp Koch

network activity and neurotransmitter release . 01/2017-12/2018. Abstract The research goals of SP11 are to study the electrophysiological properties of m/hiPSCs deriving from SP3, to compare local field [...] Forschungsgemeinschaft SFB 636: Addiction and the nucleus accumbens. 06/2012-12/2015. Abstract We are planning to monitor changes in synaptic strength in the nucleus accumbens in vivo via chronically implanted [...] beta-adrenergic agonists, however, we were able to induce long-term potentiation (LTP) instead of LTD, and are therefore currently examining the underlying mechanisms. Köhr G, Li SB. : CSC China Scholarship Council:

available to treat AUD are rarely used because their effects are small when given to all patients. However, these effects can be increased and side effects can be reduced when the drugs are given to specific [...] mifepristone) and see if their effects on abstinence, alcohol use, and wellbeing, and their side effects are different between the genders and sexes. We expect that this will result in recommendations as to which [...] (DLPFC) in individuals with SUD, the characteristic craving for a substance can be reduced. As there are divergent findings on efficacious setups for tDCS as an add-on treatment in SUD (e.g. effects on inhibitory

underlying OT effects are far from clear. Although there are no doubts that OT promotes sexual behavior, the OT circuits orchestrating precopulatory behavior viaforebrain regions are largely unknown. To [...] Emotional disorders such as distress, anxiety, and depression are frequently accompanied by chronic pain, while chronic pain sufferers are predisposed to developing these conditions. Notably, social and [...] dysfunctions are consolidated. However, it is conceivable that a treatment with OT early in life, when the plastic capacity of the brain is at a maximum and the social and behavioral dysfunctions are not co