it is used much less frequently. This could be due to the fact that, in contrast to adults, there are no large studies on the safety and effectiveness of this treatment method in children and adolescents [...] offered ECT as a treatment option for adolescents with severe depressive and psychotic disorders. There are often very long waiting times for ECT and hardly reasonable travel distances for parents and their
modulates different behaviors related to sociality, sexuality, fear, pain and others. Its effects are mediated via its action throughout the brain as a neuropeptide as well as throughout the periphery
neuronal ensembles in reward-seeking processes. 04/2021-03/2022. Abstract Our daily life activities are driven by rewards which can be conditioned to specific stimuli and environmental contexts. Reward-seeking [...] alcoholism, including advanced conditional knockout mice and viral vector gene transfer. Our experiments are aimed 1) to establish the intracellular co-localization of D1 and CRHR1 receptors in the amygdala of [...] improve our understanding of amygdala function in alcohol dependence, to identify mechanisms that are specific for this region and, in a broader perspective, to contribute to a better understanding of
psychiatric questions. This includes, for example, the role of certain networks in the brain that are important for human behaviour and learning. However, for ethical reasons, cellular and molecular mechanisms [...] specific network in the mouse in the MRI, in which expectations triggered by environmental stimuli are updated by recent experiences. In this network, the researchers showed for the first time that two
09/2012-02/2015. Abstract Schizophrenia patients suffer from a broad variety of cognitive deficits that are very often resistant to antipsychotic treatment and interfere with the social and vocational rehabilitation [...] Besides the domains represented in the MATRICS battery, it has been shown that metacognitive capacities are impaired in schizophrenia, leading to a reduced ability to select appropriate responses, to appraise [...] alterations (4;5), and finally deficits in mentalizing and social cognition („theory of mind“: ToM) (6;7), are thought to contribute to development and maintenance of delusions (8-10). Specific therapeutic int
for 50 years. I would like to express my appreciation and thanks to all employees of the CIMH, who are committed to research, teaching and patient care every day. I would like to congratulate them on their [...] Foundation form scientific bridges between Heidelberg University and the CIMH. The scientists involved are investigating the causes of chronic pain, control mechanisms in addictive disorders and the biological [...] ever before, modern technologies such as smartphones, machine learning and artificial intelligence are helping to collect and analyze insightful data. He describes a perspective that gives us hope: “In
social cues. In particular, we found that BPD patients experience happy faces as less intense and are less confident during their evaluation. They evaluate particularly positive information referenced [...] positive social information in memory, and the guidance of action based on positive social experiences are impaired in BPD patients. Effects will be measured by means of overt behavior, psychophysiological [...] al., 2009). There is ample evidence that after traumatic experience acute memories for these events are repeatedly reactivated for a certain amount of time which allows for the incorporation of new information
progress in the understanding of phantom limb pain (PLP), we still do not know which factors are antecedents and which are consequences of the pain and how central, peripheral and psychological factors interact [...] clinically-orientated approaches to understanding behaviour (Mannheim). The overall projects goals are to: a) develop a new model of pain-reward interactions that explains data from behavioural experiments [...] experimentally testable versions, we wish to examine to what extend the experiences of pain and suffering are centered in the private experience or in a person’s social and cultural interaction with the others
Research Center in the field of cellular and molecular biomarker research is also available. All partners are linked by many years of intensive collaboration. Comprehensive involvement of service users The conceptual [...] Meyer-Lindenberg , director and chairman of the board of the CIMH and site coordinator of ZIHUb. „We are very pleased that we now have the opportunity to contribute this expertise to the new German Center
Germany in the 2last years speak languages such as Arabic that are not understood by the resident therapeutic community, interpreters are scarce and not available around the clock or in emergency situations [...] addicted. Substance use disorders (SUDs) generate the largest disease burden and are categorized by DSM-5 and ICD11. SUDs are defined by compulsive drug use, craving, and re-lapses that can occur even after [...] and stimulants. One fundamental question in psy-chiatric research is: “How distinct are the different SUDs and what are the shared pathological phenomena?” Here we aim to determine the extent to which alcohol
