PTSD. Primary aims are to provide evi-dence that TF-CBT exceeds spontaneous remission and to assess maintenance of treatment gains at 6 and 12 months post-treatment. Secondary aims are to evaluate the e [...] psychiatric disorders, conclusive pathways to brain endophenotypes of social and antisocial behavior are largely missing. A combination of research of the long-term effects of early environmental adversity [...] environmental characterisation of each adolescent participant. 2. Assure that all assessment procedures are piloted and validated for use in English, French and Germanspeaking adolescent populations. 3. Develop

prevalent and characterized by devastating health and social consequences. To date, only a few medications are approved for its treatment, all of whom suffer from modest effect sizes, leaving much room for improvement