other therapies have not been or are no longer effective. The study treatment consists of two dosing sessions of about six hours each, six weeks apart. In addition, there are a total of three preparatory sessions [...] studies conducted to date indicate that psilocybin is safe and well tolerated when personal risk factors are excluded and it is administered in a controlled therapeutic setting. Those studies have also shown [...] sessions and four integration sessions, in which the experiences of the dosing sessions are reflected upon and discussed with the therapists to achieve the highest therapeutic benefit. In the dosing sessions

Research ”. How memory is formed Oliveira and her research group are primarily concerned with how memory is formed in the brain and how memories are stored over time. The goal of the effort is to uncover the [...] molecular and cellular processes involved in the formation and persistence of memory. The researchers are studying the molecular signaling pathways as well as the transcriptional and epigenetic regulation

Institute of Mental Health (CIMH) in Mannheim continues to develop positively. Almost 1,700 employees are working together with expertise and great dedication to support people with mental illnesses. The annual [...] cultural differences make it difficult to access treatment services, while those providing treatment are often unsure how to deal with foreign cultures. The new Transcultural Outpatient Clinic at the CIMH [...] treatment in psychiatry. Linking treatment and medical research Every year, around 16,000 patients are treated at the CIMH as inpatients, day patients or outpatients. Every single person has their own health

diagnostics and treatment options are most suitable. Patients can also be recommended to take part in relevant studies that contain treatment elements. “Overall, we are experiencing a high level of acceptance [...] voluntarily support medical research with their data. In addition, broad, standardized diagnostics are carried out in which data is collected as a basis for further treatment. The DAZ thus forms an important [...] and within the DZPG, as well as nationwide via the MII. “Experience to date has shown that patients are very willing to make all or part of their data available for research. Especially when they see that

innovation campus projects are being established and funded by the state as symbols of cutting-edge research in strategically relevant areas in Baden-Württemberg. The innovation campuses are established where the [...] addition, completely new forms of therapy are being developed, such as the use of artificially produced and customised immune cells. Early clinical studies are also to be promoted in order to bring the [...] Long-term funding is being coordinated. Permanent funding is being discussed “The health and life sciences are a central pillar of the state’s future”, said Science Minister Theresia Bauer in Stuttgart. She added

schizophrenia have shown that NSS are associated with abnormal cortical and subcortical structure and function. Yet, it still remains unclear whether these findings are associated with neuropathological [...] delineation using active learning. By training supportive machine learning algorithms on the fly that are custom tailored to the respective analysis pipeline used to obtain the tractogram as well as to the [...] catatonia as well as an in-depth understanding of (patho)physiologically-relevant mechanisms that are essential for advancing precision-medicine–informed treatment options for catatonia. DFG - Deutsche

beneficially contributes to abstinence. We are therefore investigating whether tDCS has a positive effect on this impulse inhibition and the success of the therapy and are also measuring brain wave patterns in [...] It is estimated that 108 million people worldwide are addicted to alcohol, and almost 40 million have an addiction to illegal drugs. In 2019, 168,000 people worldwide died from alcohol abuse and it was [...] Modulating neuronal activity in the brain In the project, patients with various addictive disorders are examined and additionally treated with transcranial direct current stimulation (tDCS) during their

Weinsberg, the ZfP Südwürttemberg, the entire PZN and Ulm University Hospital are now also joining in. In order to help parents who are less severely affected by their illness, special attention will be paid [...] child protection measures are being developed and introduced at all participating clinics. These include, for example, the standardized recording of parenthood: all patients are specifically asked whether [...] and addiction into contact with the appropriate counseling centers and support facilities while they are still in hospital, thus ensuring long-term help. In addition, extensive cooperation has been established

Children with LIS1 – Lissencephaly are born with a brain in which the typical furrows and convolutions are severely reduced or completely absent. This rare genetic disorder leads to severe developmental [...] affected, the diagnosis often means great uncertainty, as the causes and progression of the disease are still poorly understood. Organoid provides insight into the course of the disease An international [...] shape and stability thanks to an inner scaffold, the cytoskeleton. One of its essential components are so-called microtubules, tiny tubular structures inside the cell. The current study shows that the genetic

Current treatments are symptomatic but do not stop the underlying disease process. Using biomarkers, we can detect biochemical changes that show when neurons start to die. There are also biochemical tests [...] The current state-of-the-art of the treatment of these symptoms is still unsatisfactory and there are many unmet needs in this area. The major objective of the project will be to assess the effectiveness [...] eness of the proposed intervention will be tested in the prospective study. The expected benefits are socially appreciable: improving quality of life of persons with dementia, lessening caregivers' burden