of the virus,” says Rainer Spanagel. The lung is considered a very susceptible organ for infection with SARS-CoV2. Thus, acute respiratory distress syndrome (ARDS) often occurs in cases of serious covid-19 [...] triggered that kills the virus in the cells. One of the initial factors for this cascade is MAS, a gene with anti-inflammatory effect, which is therefore a protective factor in relation to the corona disease [...] may have a potential effect on overall corona infection risk and favoring complications associated with the disease. Clarifying epidemiological studies in patients are urgently needed to further investigate
significant reduction in animal experiments at the ZI. With the new 3R Center, we can identify further potential and strengthen animal protection together with our partners," says Prof. Dr. Rainer Spanagel , [...] animal experiments also take place. Therefore, the issue of animal welfare is of particular importance. With the 3R Center Rhine-Neckar, the Baden-Württemberg Ministry of Science, Research and the Arts is now [...] continuously address the issue of animal welfare but also to improve the overall quality of research. With its focus on 'Refine' and 'Reduce', the 3R Center Rhine-Neckar ideally complements the '3R Center
activities of the 3R network show that both belong together," says Science Minister Petra Olschowski. "With our 3R network Baden-Württemberg, we want to actively contribute to advancing the development and [...] are already providing valuable results. However, it will be decades, if ever, before we can dispense with animal testing," says Prof. Dr. Andreas Meyer-Lindenberg , Head of the Executive Board of the CIMH [...] attend training courses on the 3R principles. One focus of the work is the implementation of research with a view to good research practice and solid data. To this end, the existing 3R principles are being
professor. The professorship for “Cancer Survivorship and Psychological Resilience” was newly established with a grant from the Hector Foundation II to the German Cancer Research Center. It is part of the DKFZ [...] regulation, as well as possible dysfunctions of these mechanisms in affective disorders and in people with cancer. One of the aims of the professorship is to improve the mental health and quality of life of
Science, Research, and the Arts of Baden-Württemberg and Chairman of the CIMH Supervisory Board. "With his successful work as the commercial director, Dr. Janta has provided crucial impetus for the further [...] organization. He effectively secured, supported, and promoted our dynamic development. I look back with gratitude on four productive and trusting years together on the CIMH board," adds Prof. Dr. Andreas
The behavioral disorders observed in autism are associated with a multitude of genetic alterations. Scientists from the Hector Institute for Translational Brain Research (HITBR) have now found another [...] towards muscle or connective tissue, for example. Mutations in MYT1L have been found in some patients with neurological diseases, such as schizophrenia and epilepsy, but also in brain malformations. In their [...] e, which is supposed to prevent epileptic seizures. When MYT1L-deficient nerve cells were treated with lamotrigine, their electrophysiological activity returned to normal. In mice, the drug was even able
study app about their mood, their feelings, what they were currently doing, whether they were alone or with others. The further context, for example whether a stressful event has occurred, is also determined [...] stress changes. “We know from other studies that stress reactivity is significantly higher in people with psychosis or other mental illnesses than in the control group,” says Schick. The researchers have [...] everyday life. “An exercise is explained in a short video and participants can practise for a week. With compassion-oriented exercises, it takes a while to master the exercise,” says Schick. “Based on the
concept, his team has successfully demonstrated the existence of an oxytocin engram of fear memory, with specific oxytocin circuits transmitting noxious and non-noxious stimuli into pain and social behaviours [...] y dissect the property and kinetics of endogenous neuropeptide action. Openly sharing these tools with more than 40 labs around the world, he has been able to provide significant stimulus to progress in [...] clinical research. The award is accompanied by a prize of 10,000 Euro, which the winner may share with junior collaborators. ECNP is an independent scientific association whose mission is to advance the
the Institute of Psychopharmacology , with the AREC Award 2024. The annual award recognizes his leading contributions to improving ethical standards of research with animals. The citation states: “Prof.
Most psychiatric disorders are very complex: biographical, biological, and social factors interact with one another. Modern imaging methods enable us to examine the function of patients' brains to better [...] standardized processes, the Center for Innovative Psychiatric and Psychotherapeutic Research (ZIPP) with its wide range of technologies, and the biobank. In the past few months, we have also established [...] for identify patterns in highly complex data sets. For this approach, scientific data is combined with information from clinical care to provide information about the respective success of treatment. From