safety instructions are hypothesized to inhibit fear acquisition and/or to accelerate extinction learning. Attentional processes, psychophysiological responding, and behavioral measures are examined to link [...] can be amazingly persistent – even when the aversive outcomes are never experienced – the implications for a range of anxiety disorders are evident. Paret C. DFG - Deutsche Forschungsgemeinschaft PA 3107/1-1: [...] while they receive residential Dialectical Behavior Therapy (DBT) treatment. In addition, outcomes are assessed from a control group with same sample size who do not receive the treatment. Feasibility trial:

psychiatric disorders, conclusive pathways to brain endophenotypes of social and antisocial behavior are largely missing. A combination of research of the long-term effects of early environmental adversity [...] possibly attributable to the presence of distinct (e.g. arousal- specific) subgroups within AB, which are not yet very well characterized and would need more individualized treatments. In the first project [...] ized treatment. Through innovative, individualized biofeedback training protocols, young patients are learning how to self-regulate their arousal level (up- or downwards), depending on their “aggressotype”

to what extent the effects of the knock-out on brain structure and function are reversible by treatment. Both approaches are complementary and serve our long-term goal to understand the interaction of [...] has been hard to take these findings from the bench to the clinic. We think there are three major bottlenecks that are holding the field back: i) a lack of pathophysiologically-accurate animal models guiding [...] to any other approved procedure. Thus, new treatment options for therapy resistant depression (TRD) are urgently needed. A better understanding of the underlying brain circuits of depression has led to the

while they receive residential Dialectical Behavior Therapy (DBT) treatment. In addition, outcomes are assessed from a control group with same sample size who do not receive the treatment. Feasibility trial:

human population, but treatment options are very limited. Rational strategies for design and development of novel, evidence based therapies for alcohol addiction are still missing. Alcohol dependence is [...] (DLPFC) in individuals with SUD, the characteristic craving for a substance can be reduced. As there are divergent findings on efficacious setups for tDCS as an add-on treatment in SUD (e.g. effects on inhibitory [...] II: Neuroimaging x genetics . 01/2017-12/2018. Abstract In SP10 neuroimaging x genetics predictions are studied (see Fig. 2). During the first two years data collection of neuroimaging, neuropsychology,

knowledge of cellular and network effects of these substances, knowledge about contexts in which these are released remains vague and correlating the effects of neuromodulators with specific behavioral situations [...] learning signal that may drive adaptive processes in DA-innervated target regions. These processes are also thought to be of major clinical relevance in addiction, posttraumatic stress and anxiety disorders

Deutschland (UÄVD e.V), und dem Nationalen Programm für psychische Gesundheit in der Ukraine „How are you?“ Українські біженці: зробити підтримку ментального здоров’я доступнішою українською Sie möchten

The classic form is caused by mutations in the transcriptional regulator MECP2. Effective therapies are not currently available and gene editing based on CRISPR/Cas9 combined with Homology Directed Repair

Hausner L , Ticozzi N, Froelich L , Weishaupt JH, Verde F, Otto M. Phosphorylated tau 181 and 217 are elevated in serum and muscle of patients with amyotrophic lateral sclerosis . Nat Commun . 2025 16(1):2019

Diana Avetyan Lucía Colodro Conde QIMR Berghofer Medical Research Institute Stephan Ripke Join We are confident that together we will be able to address many relevant questions of the field. If you would [...] contact you: First Name * Last Name * Institution * Email * Disclaimer Areas marked with an asterisk * are mandatory fields. Please also note the privacy policy of the CIMH. Submit Publications Relevant pu [...] Environmental Causes of Individual Differences in Borderline Personality Disorder Features and Loneliness are Partially Shared. Twin Res Hum Genet, 23(4), 214-220. https://doi.org/10.1017/thg.2020.62 Sanchez-Roige