Philipsen A. Sulcal Depth and Genetic Susceptibility influence initial Treatment Response in Adults with Attention-Deficit/Hyperactivity Disorder . Biol Psychiatry Cogn Neurosci Neuroimaging . 2025 Sep 20

recently stored memory. We will examine healthy subjects and unmedicated patients with high proneness for dissociation (patients with BPD and complex PTSD). Differential fear conditioning will be applied following [...] co-players, fail to adjust their expectancies particularly in case of positive feedback and react with a drop of cooperative behavior in case of a provocation when previously included by social partners [...] processes such as behavioral matching, i.e. mimicry and synchronized action, and their interplay with the sensitivity to social reward, the storage of positive social information in memory, and the guidance

Open-Label, Study To Evaluate The Long-Term Safety Of Ecopipam Tablets In Children, Adolescents And Adults With Tourette’s Disorder. 07/2024-07/2027. Banaschewski T. EU - Europäische Union 847879: PRIME - Prevention [...] will be involved in the optimization of domain-specific (i.e. task-fMRI) analysis pipelines, along with the harmonization of the data to a common standard. Building upon these analyses, CIMH will contribute [...] stratification markers based on existing EU-AIMS and new LEAP data sets as well as by integrating data with other existing cohorts. Häge A. Servier Deutschland GmbH : Bumetanide in Autism. 12/2018-12/2021.

. Intranasal oxytocin blunts amygdala response to negative affective stimuli in males and females with alcohol use disorder: a randomized controlled cross-over trial . Psychopharmacology (Berl) . 2025

Scholz I, Koppe G, Kirsch P, Gerchen M . Self-referential belief shares common neural correlates with general belief . Sci Rep . 2025 15(1):2137. Sacu S , Hermann A, Banaschewski T, Gerchen M , Holz NE

will be validated by a new optogenetic tool, which allows selectively modifying neuronal ensembles with improved temporal control and specificity. In summary, our approach will give insight into the function [...] hyper-dopaminergic state that drives alcohol craving (Hirth et al., 2015), and finally (iv) established with a collaborator from NIAAA, Bethesda USA, a database of brain miRNA profiles from the prefrontal cortices [...] there exist DA D1 and CRHR1 receptor rich neuronal populations - the intercalating cell masses (ICM) - with important gating functions for intra-amygdala signal flow. We hypothesize that within these cells

created with BodyParts3D Paraventricular (red) and Supraoptic (blue) nucleus of the hypothalamus The Oxytocin Network Learn more about the operational principle of Oxytocin! Viral Vectors Learn how viruses [...] selected highlights in the 2022 ERC synergy grants . Zum deutschen Artikel We are proud to work together with great teams all over the world Our key collaborators Profs. Philipp Koch and Rainer Spanagel (CIMH/ZI

in animals, and which can be transferred to humans. With our highly interdisciplinary EU consortium (PIs from seven European countries and Israel with outstanding expertise) it is expected that after having [...] missing. Alcohol dependence is characterized by cycles of excessive alcohol consumption, interspersed with intervals of abstinence, and frequent relapses. Relapse is a key element of this disease process and

vague and correlating the effects of neuromodulators with specific behavioral situations is difficult. Olfactory system modulation by oxytocin provides with a unique opportunity to directly ask how neural [...] learning in those situations. We here propose the fact that oxytocin release can be reliably associated with certain behavioral states to use it as a model system for modulation of brain states and associated [...] task periods during which dopamine input is most crucial, how dopamine neuron activity is coordinated with PFC activity as the task progresses, and how it impacts on various subcomponents of rule learning

analytical and clinical validity. The latter depends on qualifying measures linking peripheral biomarkers with a biological process and clinical endpoints of schizophrenia. Thus, biomarker signatures identified [...] faithfully represent the genetic background of individual patients. To this end, iPSC clones from patients with schizophrenia will be delivered by partners LMU and CIMH. Diagnostic and imaging data as well as blood [...] isolating and sequencing of individual nuclei from snap-frozen brain samples obtained from patients with other neuropsychiatric diseases. In parallel we will use standardized human iPSC-derived forebrain