The Association Between Newer Generation Antidepressants and Insomnia in Children and Adolescents With Major Depressive Disorder . J Am Acad Child Adolesc Psychiatry . 2025 64(10):1148-1164. Epub 2025 [...] administration reduces alcohol craving and cue-induced nucleus accumbens activation in individuals with alcohol use disorder: the double-blind randomized controlled ICONIC trial . Mol Psychiatry . 2025

learning on cultural differences in social cognition with a cross-sectional approach by comparing participants from China and Germany who live abroad with those who never lived abroad. EU - Europäische Union [...] in animals, and which can be transferred to humans. With our highly interdisciplinary EU consortium (PIs from seven European countries and Israel with outstanding expertise) it is expected that after having [...] specific neurobiological mechanisms associated with therapy response as well as particular neurobiological signatures before treatment that are associated with treatment response. Results should further allow

namely a preclinical multicenter placebo controlled trial in rats with a step-wise translation into a naturalistic pilot trial with ambulatory assessment in alcoholic patients. As a comparator, we will [...] in animals, and which can be transferred to humans. With our highly interdisciplinary EU consortium (PIs from seven European countries and Israel with outstanding expertise) it is expected that after having [...] placebo vs acamprosate – which is a clinically effective medication. These data will be contrasted with a 3-arm design in male and female alcohol addicted rats where two doses of intranasally applied OXY

Evaluation of a Smartphone App Intervention with Telephone Guidance as Transitional Support from Inpatient Treatment to Continuing Care for Individuals with Alcohol Use Disorder: Results from a Randomized

reduce cognitive deficits and substance craving in individuals with substance use disorders (SUD) of different kinds. In individuals with SUD, functional neuroimaging and neuropsychological tasks have [...] and associated underlying neuronal networks observed to be affected in individuals with AUD overlap significantly with those that could be strengthened by chessbased cognitive training or formal chess. [...] changes. Further, by applying tDCS over the dorsolateral prefrontal cortex (DLPFC) in individuals with SUD, the characteristic craving for a substance can be reduced. As there are divergent findings on

in adult patients with alcohol addiction, (iv) to expand the NGFNplus sample by including a new set of healthy subjects with high genetic risk (1st degree relatives of patients with alcohol addiction) [...] characterize longitudinal outcomes in patients with alcohol addiction (5 years following our index session) and to complement the NGFN-sample with an add-on study with 1st degree relatives that will allow us [...] reduce cognitive deficits and substance craving in individuals with substance use disorders (SUD) of different kinds. In individuals with SUD, functional neuroimaging and neuropsychological tasks have

olfactory inputs have the most direct access to the limbic system and evoke innate and learned behaviors with lasting aversive and appetitive memories. The olfactory system maintains stem cell niches providing [...] t period. In parallel, we study the postnatal developmental trajectory of the dopaminergic system with similar aims to dissect genetic and environmental influences on mature circuit properties. These limbic

Open-Label, Study To Evaluate The Long-Term Safety Of Ecopipam Tablets In Children, Adolescents And Adults With Tourette’s Disorder. 07/2024-07/2027. Grimmer Y, Koopmann A. Dietmar Hopp Stiftung gGmbH 1DH2311081: [...] will be involved in the optimization of domain-specific (i.e. task-fMRI) analysis pipelines, along with the harmonization of the data to a common standard. Building upon these analyses, CIMH will contribute [...] stratification markers based on existing EU-AIMS and new LEAP data sets as well as by integrating data with other existing cohorts. Häge A. Servier Deutschland GmbH : Bumetanide in Autism. 12/2018-12/2021.

effects on sensory integration associated with body perception and the processing of somatosensory stimuli with positive or negative valence, and their association with dissociation. By revealing the psych [...] trauma experience) will be enhanced by including participants with moderate to high levels of social and trait anxiety, as well as individuals with adverse childhood experiences. In addition, an intensified [...] administered to N=22 patients with BPD while they receive residential Dialectical Behavior Therapy (DBT) treatment. In addition, outcomes are assessed from a control group with same sample size who do not

Philipsen A. Sulcal Depth and Genetic Susceptibility influence initial Treatment Response in Adults with Attention-Deficit/Hyperactivity Disorder . Biol Psychiatry Cogn Neurosci Neuroimaging . 2025 Sep 20