administered to N=22 patients with BPD while they receive residential Dialectical Behavior Therapy (DBT) treatment. In addition, outcomes are assessed from a control group with same sample size who do not [...] recently stored memory. We will examine healthy subjects and unmedicated patients with high proneness for dissociation (patients with BPD and complex PTSD). Differential fear conditioning will be applied following [...] Abstract In the planned set of studies, we will use neurofeedback to augment psychotherapy in patients with Borderline Personality Disorder (BPD) at risk for failure to benefit from psychotherapy treatment
isolating and sequencing of individual nuclei from snap-frozen brain samples obtained from patients with other neuropsychiatric diseases. In parallel we will use standardized human iPSC-derived forebrain [...] WP2: A human brain Organoid-based addiction circuitry to investigate molecular changes associated with SUDs. 11/2019-10/2022. Ladewig J. DFG - Deutsche Forschungsgemeinschaft LA 2933/3-1 : MECPer-3D: [...] MECP2. Effective therapies are not currently available and gene editing based on CRISPR/Cas9 combined with Homology Directed Repair appears an appealing option for the development of new therapeutic approaches
Leitung Prof. Dr. med. Dr. med. vet. Hannelore Ehrenreich E-Mail Beschreibung Translational Neuroscience with focus on: (1) Genetic and environmental underpinnings of neuropsychiatric diseases; (2) Endogenous
Cue-Induced Alcohol Craving, Stress Response, Negative Affect and Reward System Response in Individuals with Alcohol Use Disorder. Abstract Alcohol use disorder (AUD) is highly prevalent and characterized by [...] consumption and modulates brain circuits that mediate drug seeking. First clinical data in patients with opioid use disorder indicated significant craving-reducing effects of CBD, already one hour after [...] seek to conduct a randomized-controlled double-blind proof-of-principle study in N=26 individuals with AUD to investigate actions and neurobiological mechanisms of CBD in AUD, by assessment of CBD’s effects
digital health tool, Digital Mobile Mental Health (DMMH), in close collaboration with stakeholders and extending it with mobile sensing data and innovative machine learning models. DMMH consists of an ESM [...] transfer and scale-up of DMMH to routine mental health clinical practice by closely collaborating with relevant stakeholders, aligning the innovative DMMH tool to their needs. Similarly, the diverse ethical
Frontalhirn nach EPO/Hypoxie. Ehrenreich H. EU - Europäische Union : ALTIBRAIN (ERC Consolidator Grant with Kamilla Miskowiak, Denmark). Ehrenreich H. EU - Europäische Union : BREPOCI: The brain erythropoietin
effects on sensory integration associated with body perception and the processing of somatosensory stimuli with positive or negative valence, and their association with dissociation. By revealing the psych [...] behavior in VR competitive games and (2) to pilot-test these with virtual doppelganger avatars of the respectively two players interacting with each other. DFG - Deutsche Forschungsgemeinschaft BA 2088/7-1 [...] learning on cultural differences in social cognition with a cross-sectional approach by comparing participants from China and Germany who live abroad with those who never lived abroad. DFG - Deutsche Fors
About me: I am a Master student in molecular biosciences with a Major in neuroscience. After neuroscientific research sparked my interest during my Bachelor studies, I joined Valery Grinevich´s lab to
interview with an administration time of approximately 15 minutes that is employed in more than 100 countries. Second, we will validate this tool against the gold standard of expert diagnosis with a human [...] digital health tool, Digital Mobile Mental Health (DMMH), in close collaboration with stakeholders and extending it with mobile sensing data and innovative machine learning models. DMMH consists of an ESM [...] trial in rats as a preclinical confirmatory proof. We aim to confirm the hypothesis that treatment with exosomes will have long-lasting positive effects on relapse behaviour in animal models of alcohol
recently stored memory. We will examine healthy subjects and unmedicated patients with high proneness for dissociation (patients with BPD and complex PTSD). Differential fear conditioning will be applied following [...] 3. Biomaterial collection 4. Coordinating allocation of funds to the individual projects together with the administration of the CIMH as well as Heidelberg University. 5. Coordinating assignments of the [...] co-players, fail to adjust their expectancies particularly in case of positive feedback and react with a drop of cooperative behavior in case of a provocation when previously included by social partners
