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Dr. Marina Eliava

Senior Researcher

Abteilung Neuropeptidforschung in der Psychiatrie

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About me

The population of oxytocin-synthesising neurons in the rodent brain is relatively small, and direct innervation of distant structures is sparse. Nevertheless, experimental release of oxytocin (OT) in distant structures usually results in robust facilitation of various components of social behaviour. I am curious to know how OT-sensitive local microcircuits in various brain structures (such as the ventral hippocampus, the dorso-medial prefrontal cortex and the entorhinal cortex) are arranged. What types of neurons are they made up of, and do they share any neuroanatomical features?

Expertise

ImmunohistochemistryStereotactic neurosurgery
Correlative light and electron microscopyNeural tract tracing techniques

 

Publikationen in peer-reviewed Zeitschriften seit 2006

TOP 5 Publikationen:

  1. Wahis J, Baudon A, Althammer F, Kerspern D, Goyon S, Hagiwara D, Lefevre A, Barteczko L, Boury-Jamot B, Bellanger B, Abatis M, da Silva Gouveia M, Benusiglio D, Eliava M, Rozov A, Weinsanto I, Knobloch-Bollmann HS, Kirchner MK, Roy RK, Wang H, Pertin M, Inquimbert P, Pitzer C, Siemens J, Goumon Y, Boutrel B, Lamy CM, Decosterd I, Chatton JY, Rouach N, Young WS, Stern JE, Poisbeau P, Stoop R, Darbon P, Grinevich V, Charlet A. Astrocytes mediate the effect of oxytocin in the central amygdala on neuronal activity and affective states in rodents.Nat Neurosci. 2021 24(4):529-541. Epub 2021 Feb 15.
  2. Tang Y, Benusiglio D, Lefevre A, Hilfiger L, Althammer F, Bludau A, Hagiwara D, Baudon A, Darbon P, Schimmer J, Kirchner MK, Roy RK, Wang S, Eliava M, Wagner S, Oberhuber M, Conzelmann KK, Schwarz M, Stern JE, Leng G, Neumann ID, Charlet A, Grinevich V. Social touch promotes interfemale communication via activation of parvocellular oxytocin neurons.Nat Neurosci. 2020 23(9):1125-1137. Epub 2020 Jul 27.
  3. Wirth S, Soumier A, Eliava M, Derdikman D, Wagner S, Grinevich V, Sirigu A. Territorial blueprint in the hippocampal system.Trends Cogn Sci. 2021 25(10):831-842.
  4. Knobloch HS, Charlet A, Hoffmann LC, Eliava M, Khrulev S, Cetin AH, Osten P, Schwarz MK, Seeburg PH, Stoop R, Grinevich V. Evoked axonal oxytocin release in the central amygdala attenuates fear response.Neuron. 2012 73(3):553-66.
  5. Hasan MT, Althammer F, Silva da Gouveia M, Goyon S, Eliava M, Lefevre A, Kerspern D, Schimmer J, Raftogianni A, Wahis J, Knobloch-Bollmann HS, Tang Y, Liu X, Jain A, Chavant V, Goumon Y, Weislogel JM, Hurlemann R, Herpertz SC, Pitzer C, Darbon P, Dogbevia GK, Bertocchi I, Larkum ME, Sprengel R, Bading H, Charlet A, Grinevich V. A Fear Memory Engram and Its Plasticity in the Hypothalamic Oxytocin System.Neuron. 2019 103(1):133-146. Epub 2019 May 13.

Zentralinstitut für Seelische Gesundheit (ZI) - https://www.zi-mannheim.de