Althammer F, Wimmer MC, Krabichler Q, Küppers S, Schimmer J, Fröhlich H, Dötsch L, Gruber T, Wunsch S, Schubert T, Kirchner MK, Stern JE, Charlet A, Grinevich V, Schaaf CP. Analysis of the hypothalamic oxytocin system and oxytocin receptor-expressing astrocytes in a mouse model of Prader-Willi syndrome. J Neuroendocrinol. 2022 34(12):e13217. Epub 2022 Dec 1.
Bach P, Reinhard I, Koopmann A, Bumb JM, Sommer WH, Vollstädt-Klein S, Kiefer F. Test-retest reliability of neural alcohol cue-reactivity: Is there light at the end of the magnetic resonance imaging tube?. Addict Biol. 2022 27(1):e13069. Epub 2021 Jun 15.
Bach P, Schuster R, Koopmann A, Vollstädt-Klein S, Spanagel R, Kiefer F. Plasma calcium concentration during detoxification predicts neural cue-reactivity and craving during early abstinence in alcohol-dependent patients. Eur Arch Psychiatry Clin Neurosci. 2022 272(2):341-348. Epub 2021 Feb 25.
Barini E, Plotzky G, Mordashova Y, Hoppe J, Rodriguez-Correa E, Julier S, LePrieult F, Mairhofer I, Mezler M, Biesinger S, Cik M, Meinhardt M, Ercan-Herbst E, Ehrnhoefer DE, Striebinger A, Bodie K, Klein C, Gasparini L, Schlegel K. Tau in the brain interstitial fluid is fragmented and seeding-competent. Neurobiol Aging. 2022 109:64-77.
Bilbao A, Spanagel R. Medical cannabinoids: a pharmacology-based systematic review and meta-analysis for all relevant medical indications. BMC Med. 2022 20(1):259.
Bordier C, Weil G, Bach P, Scuppa G, Nicolini C, Forcellini G, Perez-Ramirez U, Moratal D, Canals S, Hoffmann S, Hermann D, Vollstädt-Klein S, Kiefer F, Kirsch P, Sommer WH, Bifone A. Increased network centrality of the anterior insula in early abstinence from alcohol. Addict Biol. 2022 27(1):e13096. Epub 2021 Aug 31.
Ekhtiari H, Zare-Bidoky M, Sangchooli A, Janes AC, Kaufman MJ, Oliver JA, Prisciandaro JJ, Wüstenberg T, Anton RF, Bach P, Baldacchino A, Beck A, Bjork JM, Brewer J, Childress AR, Claus ED, Courtney KE, Ebrahimi M, Filbey FM, Ghahremani DG, Azbari PG, Goldstein RZ, Goudriaan AE, Grodin EN, Hamilton JP, Hanlon CA, Hassani-Abharian P, Heinz A, Joseph JE, Kiefer F, Zonoozi AK, Kober H, Kuplicki R, Li Q, London ED, McClernon J, Noori HR, Owens MM, Paulus MP, Perini I, Potenza M, Potvin S, Ray L, Schacht JP, Seo D, Sinha R, Smolka MN, Spanagel R, Steele VR, Stein EA, Steins-Loeber S, Tapert SF, Verdejo-Garcia A, Vollstädt-Klein S, Wetherill RR, Wilson SJ, Witkiewitz K, Yuan K, Zhang X, Zilverstand A. A methodological checklist for fMRI drug cue reactivity studies: development and expert consensus. Nat Protoc. 2022 17(3):567-595. Epub 2022 Feb 4.
Foo JC, Meinhardt M, Skorodumov I, Spanagel R. Alcohol solution strength preference predicts compulsive-like drinking behaviour in rats. Alcohol Clin Exp Res. 2022 46(9):1710-1719. Epub 2022 Jul 24.
Gerhardt S, Eidenmueller K, Hoffmann S, Bekier NK, Bach P, Hermann D, Koopmann A, Sommer WH, Kiefer F, Vollstädt-Klein S. A History of Childhood Maltreatment Has Substance- and Sex-Specific Effects on Craving During Treatment for Substance Use Disorders. Front Psychiatry. 2022 13:866019.
Guiraud J, Addolorato G, Antonelli M, Aubin HJ, de Bejczy A, Benyamina A, Cacciaglia R, Caputo F, Dematteis M, Ferrulli A, Goudriaan AE, Gual A, Lesch OM, Maremmani I, Mirijello A, Nutt DJ, Paille F, Perney P, Poulnais R, Raffaillac Q, Rehm J, Rolland B, Rotondo C, Scherrer B, Simon N, Skala K, Söderpalm B, Somaini L, Sommer WH, Spanagel R, Vassallo GA, Walter H, van den Brink W. Sodium oxybate for the maintenance of abstinence in alcohol-dependent patients: An international, multicenter, randomized, double-blind, placebo-controlled trial. J Psychopharmacol. 2022 36(10):1136-1145. Epub 2022 Jul 7.
Harel M, Perini I, Kämpe R, Alyagon U, Shalev H, Besser I, Sommer WH, Heilig M, Zangen A. Repetitive Transcranial Magnetic Stimulation in Alcohol Dependence: A Randomized, Double-Blind, Sham-Controlled Proof-of-Concept Trial Targeting the Medial Prefrontal and Anterior Cingulate Cortices. Biol Psychiatry. 2022 91(12):1061-1069. Epub 2021 Dec 6.
Knabbe J, Protzmann J, Schneider N, Berger M, Dannehl D, Wei S, Strahle C, Tegtmeier M, Jaiswal A, Zheng H, Krüger M, Rohr K, Spanagel R, Bilbao A, Engelhardt M, Scholz H, Cambridge SB. Single-dose ethanol intoxication causes acute and lasting neuronal changes in the brain. Proc Natl Acad Sci U S A. 2022 119(25):e2122477119.
Kusaka S, Yamaguchi S, Foo JC, Togo F, Sasaki T. Mental Health Literacy Programs for Parents of Adolescents: A Systematic Review. Front Psychiatry. 2022 13:816508.
Körber C, Sommer WH. From ensembles to meta-ensembles: Specific reward encoding by correlated network activity. Front Behav Neurosci. 2022 16:977474.
Meinhardt M, Giannone F, Hirth N, Bartsch D, Spampinato SM, Kelsch W, Spanagel R, Sommer WH, Hansson AC. Disrupted circadian expression of beta-arrestin 2 affects reward-related µ-opioid receptor function in alcohol dependence. J Neurochem. 2022 160(4):454-468. Epub 2022 Jan 04.
Morella I, Pohorala V, Calpe-López C, Brambilla R, Spanagel R, Bernardi R. Nicotine self-administration and ERK signaling are altered in RasGRF2 knockout mice. Front Pharmacol. 2022 13:986566.
Mullins N, Kang J, Campos AI, Coleman JRI, Edwards AC, Galfalvy H, Levey DF, Lori A, Shabalin A, Starnawska A, Su MH, Watson HJ, Adams M, Awasthi S, Gandal M, Hafferty JD, Hishimoto A, Kim M, Okazaki S, Otsuka I, Ripke S, Ware EB, Bergen AW, Berrettini WH, Bohus M, Brandt H, Chang X, Chen WJ, Chen HC, Crawford S, Crow S, DiBlasi E, Duriez P, Fernández-Aranda F, Fichter MM, Gallinger S, Glatt SJ, Gorwood P, Guo Y, Hakonarson H, Halmi KA, Hwu HG, Jain S, Jamain S, Jiménez-Murcia S, Johnson C, Kaplan AS, Kaye WH, Keel PK, Kennedy JL, Klump KL, Li D, Liao SC, Lieb K, Lilenfeld L, Liu CM, Magistretti PJ, Marshall CR, Mitchell JE, Monson ET, Myers RM, Pinto D, Powers A, Ramoz N, Roepke S, Rozanov V, Scherer SW, Schmahl C, Sokolowski M, Strober M, Thornton LM, Treasure J, Tsuang MT, Witt S, Woodside DB, Yilmaz Z, Zillich L, Adolfsson R, Agartz I, Air TM, Alda M, Alfredsson L, Andreassen OA, Anjorin A, Appadurai V, Soler Artigas M, Van der Auwera S, Azevedo MH, Bass N, Bau CH, Baune BT, Bellivier F, Berger K, Biernacka JM, Bigdeli TB, Binder EB, Boehnke M, Boks MP, Bosch R, Braff DL, Bryant R, Budde M, Byrne EM, Cahn W, Casas M, Castelao E, Cervilla JA, Chaumette B, Cichon S, Corvin A, Craddock N, Craig D, Degenhardt F, Djurovic S, Edenberg HJ, Fanous AH, Foo JC, Forstner AJ, Frye M, Fullerton JM, Gatt JM, Gejman PV, Giegling I, Grabe HJ, Green MJ, Grevet EH, Grigoroiu-Serbanescu M, Gutierrez B, Guzman-Parra J, Hamilton SP, Hamshere ML, Hartmann A, Hauser J, Heilmann-Heimbach S, Hoffmann P, Ising M, Jones I, Jones LA, Jönsson L, Kahn RS, Kelsoe JR, Kendler KS, Kloiber S, Koenen KC, Kogevinas M, Konte B, Krebs MO, Landén M, Lawrence J, Leboyer M, Lee PH, Levinson DF, Liao C, Lissowska J, Lucae S, Mayoral F, McElroy SL, McGrath P, McGuffin P, McQuillin A, Medland SE, Mehta D, Melle I, Milaneschi Y, Mitchell PB, Molina E, Morken G, Mortensen PB, Müller-Myhsok B, Nievergelt C, Nimgaonkar V, Nöthen MM, O'Donovan MC, Ophoff RA, Owen MJ, Pato C, Pato MT, Penninx BWJH, Pimm J, Pistis G, Potash JB, Power RA, Preisig M, Quested D, Ramos-Quiroga JA, Reif A, Ribasés M, Richarte V, Rietschel M, Rivera M, Roberts A, Roberts G, Rouleau GA, Rovaris DL, Rujescu D, Sánchez-Mora C, Sanders AR, Schofield PR, Schulze TG, Scott LJ, Serretti A, Shi J, Shyn SI, Sirignano L, Sklar P, Smeland OB, Smoller JW, Sonuga-Barke EJ, Spalletta G, Strauss JS, Świątkowska B, Trzaskowski M, Turecki G, Vilar-Ribó L, Vincent JB, Völzke H, Walters JT, Shannon Weickert C, Weickert TW, Weissman MM, Williams LM, Wray NR, Zai CC, Ashley-Koch AE, Beckham JC, Hauser ER, Hauser MA, Kimbrel NA, Lindquist JH, McMahon B, Oslin DW, Qin X, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium , Bipolar Disorder Working Group of the Psychiatric Genomics Consortium , Eating Disorders Working Group of the Psychiatric Genomics Consortium , German Borderline Genomics Consortium , MVP Suicide Exemplar Workgroup , VA Million Veteran Program , Agerbo E, Børglum AD, Breen G, Erlangsen A, Esko T, Gelernter J, Hougaard DM, Kessler RC, Kranzler HR, Li QS, Martin NG, McIntosh AM, Mors O, Nordentoft M, Olsen CM, Porteous D, Ursano RJ, Wasserman D, Werge T, Whiteman DC, Bulik CM, Coon H, Demontis D, Docherty AR, Kuo PH, Lewis CM, Mann JJ, Rentería ME, Smith DJ, Stahl EA, Stein MB, Streit F, Willour V, Ruderfer DM. Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors. Biol Psychiatry. 2022 91(3):313-327. Epub 2021 Sep 9.
Neuhaus W, Reininger-Gutmann B, Rinner B, Plasenzotti R, Wilflingseder D, De Kock J, Vanhaecke T, Rogiers V, Jírová D, Kejlová K, Knudsen LE, Nielsen RN, Kleuser B, Kral V, Thöne-Reineke C, Hartung T, Pallocca G, Leist M, Hippenstiel S, Lang A, Retter I, Krämer S, Jedlicka P, Ameli K, Fritsche E, Tigges J, Buettner M, Bleich A, Baumgart N, Baumgart J, Meinhardt M, Spanagel R, Chourbaji S, Kränzlin B, Seeger B, von Köckritz-Blickwede M, Sánchez-Morgado JM, Galligioni V, Ruiz-Pérez D, Movia D, Prina-Mello A, Ahluwalia A, Chiono V, Gutleb AC, Schmit M, van Golen B, van Weereld L, Kienhuis A, van Oort E, van der Valk J, Smith A, Roszak J, Stępnik M, Sobańska Z, Olsson IAS, Franco NH, Sevastre B, Kandarova H, Capdevila S, Johansson J, Cederroth CR, Sandström J, Ragan I, Bubalo N, Spielmann H. The Rise of Three Rs Centres and Platforms in Europe. Altern Lab Anim. 2022 50(2):90-120. Epub 2022 May 16.
Neuhaus W, Reininger-Gutmann B, Rinner B, Plasenzotti R, Wilflingseder D, De Kock J, Vanhaecke T, Rogiers V, Jírová D, Kejlová K, Knudsen LE, Nielsen RN, Kleuser B, Kral V, Thöne-Reineke C, Hartung T, Pallocca G, Rovida C, Leist M, Hippenstiel S, Lang A, Retter I, Krämer S, Jedlicka P, Ameli K, Fritsche E, Tigges J, Kuchovská E, Buettner M, Bleich A, Baumgart N, Baumgart J, Meinhardt MW, Spanagel R, Chourbaji S, Kränzlin B, Seeger B, von Köckritz-Blickwede M, Sánchez-Morgado JM, Galligioni V, Ruiz-Pérez D, Movia D, Prina-Mello A, Ahluwalia A, Chiono V, Gutleb AC, Schmit M, van Golen B, van Weereld L, Kienhuis A, van Oort E, van der Valk J, Smith A, Roszak J, Stępnik M, Sobańska Z, Reszka E, Olsson IAS, Franco NH, Sevastre B, Kandarova H, Capdevila S, Johansson J, Svensk E, Cederroth CR, Sandström J, Ragan I, Bubalo N, Kurreck J, Spielmann H. The Current Status and Work of Three Rs Centres and Platforms in Europe. Altern Lab Anim. 2022 50(6):381-413.
Perez-Ramirez U, López-Madrona VJ, Pérez-Segura A, Pallarés V, Moreno A, Ciccocioppo R, Hyytiä P, Sommer WH, Moratal D, Canals S. Brain Network Allostasis after Chronic Alcohol Drinking Is Characterized by Functional Dedifferentiation and Narrowing. J Neurosci. 2022 42(21):4401-4413. Epub 2022 Apr 18.
Pinger M, Thome J, Halli P, Sommer WH, Koppe G, Kirsch P. Comparing Discounting of Potentially Real Rewards and Losses by Means of Functional Magnetic Resonance Imaging. Front Syst Neurosci. 2022 16:867202.
Schmitt A, Uhrig S, Spanagel R, von Wilmsdorff M, Kalman JL, Schneider-Axmann T, Falkai P, Hansson AC. Post-mortem gene expression of calcium channels Cav1.2 and Cav1.3 in schizophrenia. Eur Arch Psychiatry Clin Neurosci. 2022 272(7):1135-1137.
Singaravelu SK, Goitom AD, Graf AP, Moerz H, Schilder A, Hoheisel U, Spanagel R, Treede RD. Persistent muscle hyperalgesia after adolescent stress is exacerbated by a mild-nociceptive input in adulthood and is associated with microglia activation. Sci Rep. 2022 12(1):18324.
Sommer WH, Canals S, Bifone A, Heilig M, Hyytiä P. From a systems view to spotting a hidden island: A narrative review implicating insula function in alcoholism. Neuropharmacology. 2022 209:108989. Epub 2022 Feb 22.
Spanagel R. Ten Points to Improve Reproducibility and Translation of Animal Research. Front Behav Neurosci. 2022 16:869511.
Streit F, Witt SH, Awasthi S, Foo JC, Jungkunz M, Frank J, Colodro-Conde L, Hindley G, Smeland OB, Maslahati T, Schwarze CE, Dahmen N, Schott BH, Kleindienst N, Hartmann A, Giegling I, Zillich L, Sirignano L, Poisel E, Chen CH, Nöthen MM, Mobascher A, Rujescu D, Lieb K, Roepke S, Schmahl C, Bohus M, Ripke S, Rietschel M, Andreassen OA. Borderline personality disorder and the big five: molecular genetic analyses indicate shared genetic architecture with neuroticism and openness. Transl Psychiatry. 2022 12(1):153.
Thome J, Pinger M, Halli P, Durstewitz D, Sommer WH, Kirsch P, Koppe G. A Model Guided Approach to Evoke Homogeneous Behavior During Temporal Reward and Loss Discounting. Front Psychiatry. 2022 13:846119.
Vengeliene V, Spanagel R. mGlu2 mechanism-based interventions to treat alcohol relapse. Front Pharmacol. 2022 13:985954.
Wei S, Li YL, Gong Q, Liang H, Bernardi R, Liang JH. Molecular chaperone heat shock protein 70 inhibitors suppress conditioned place preference induced by morphine exposure in male rats. Addict Biol. 2022 27(3):e13163.
Wetzel L, Pourbaix M, Riegler A, Pfeifer AM, Reinhard I, Hoffmann S, Vollstädt-Klein S, Kiefer F, Sommer WH, Bumb JM, Back P, Koopmann A. G-CuP: the effect of a forced oral glucose intake on alcohol craving and mesolimbic cue reactivity in alcohol dependence-study protocol of a randomized, double-blind, placebo-controlled crossover study. Trials. 2022 23(1):693.
Wilkens R, Hoffrichter A, Kleinsimlinghaus K, Bohl B, Haag C, Lehmann N, Schmidt M, Munoz Perez-Vico E, Wangemann J, Rehder K, Horschitz S, Köhr G, Ladewig J, Koch P. Diverse maturity-dependent and complementary anti-apoptotic brakes safeguard human iPSC-derived neurons from cell death. Cell Death Dis. 2022 13(10):887.
Zhang J, Wang X, Bernardi R, Ju J, Wei S, Gong Z. Activation of AMPA Receptors in the Lateral Habenula Produces Anxiolytic Effects in a Rat Model of Parkinson's Disease. Front Pharmacol. 2022 13:821975.
Zhou R, Foo JC, Yamaguchi S, Nishida A, Ogawa S, Usami S, Togo F, Sasaki T. The longitudinal relationship between sleep length and psychotic-like experiences in adolescents. Psychiatry Res. 2022 317:114893.
Zillich L, Frank J, Streit F, Friske MM, Foo JC, Sirignano L, Heilmann-Heimbach S, Dukal H, Degenhardt F, Hoffmann P, Hansson AC, Nöthen MM, Rietschel M, Spanagel R, Witt S. Epigenome-wide association study of alcohol use disorder in five brain regions. Neuropsychopharmacology. 2022 47(4):832-839. Epub 2021 Nov 13.
Zillich L, Poisel E, Frank J, Foo JC, Friske MM, Streit F, Sirignano L, Heilmann-Heimbach S, Heimbach A, Hoffmann P, Degenhardt F, Hansson AC, Bakalkin G, Nöthen MM, Rietschel M, Spanagel R, Witt SH. Multi-omics signatures of alcohol use disorder in the dorsal and ventral striatum. Transl Psychiatry. 2022 12(1):190.
Zillich L, Poisel E, Streit F, Frank J, Fries GR, Foo JC, Friske MM, Sirignano L, Hansson AC, Nöthen MM, Witt SH, Walss-Bass C, Spanagel R, Rietschel M. Epigenetic Signatures of Smoking in Five Brain Regions. J Pers Med. 2022 12(4)