Amin F, König C, Zhang J, Kalinichenko LS, Königsmann S, Brunsberg V, Riemensperger TD, Müller CP, Gerber B. Compromising Tyrosine Hydroxylase Function Extends and Blunts the Temporal Profile of Reinforcement by Dopamine Neurons in . J Neurosci. 2025 45(11):e1498242024.
Andrade FRT, Buchborn T, Thalheimer G, Meinhardt M, Joca S, de Almeida RMM. Therapeutic Use of Psilocybin in Depression: a Systematic Review of Clinical Evidence. Acta Neuropsychiatr. 2025 37:e86.
Broccoli L, Bernardi R, Giannone F, Hoppe A, Jüngling K, Borroto-Escuela DO, Rimondini-Giorgini R, Perez de la Mora M, von Bohlen und Halbach O, Fuxe K, Pape HC, Deussing JM, Spanagel R, Sommer WH, Hansson AC. Reducing stress and alcohol-related behaviors by targeting D1-CRHR1 receptor interactions in the amygdala. Front Pharmacol. 2025 16:1677510.
Chestnykh D, Kalinichenko LS, von Hörsten S, Kornhuber J, Müller CP. The mirror preference test: A reverse translational approach to study anomalous subjective experience in rats. Brain Res Bull. 2025 222:111247. Epub 2025 Feb 5.
Chestnykh D, Mühle C, Schumacher F, Kalinichenko LS, Löber S, Gmeiner P, Alzheimer C, von Hörsten S, Kleuser B, Uebe S, Ekici AB, Gulbins E, Kornhuber J, Jin HK, Bae JS, Lourdusamy A, Müller CP. Acid sphingomyelinase activity suggests a new antipsychotic pharmaco-treatment strategy for schizophrenia. Mol Psychiatry. 2025 30(7):2891-2906. Epub 2025 Jan 17.
Ciccocioppo E, Massetti S, Meinhardt M, Fumagalli F, Romualdi P, Roberto M, Spanagel R, Ciccocioppo R, Domi E. (R)-Ketamine reduces alcohol intake and alcohol seeking induced by reconsolidation of alcohol-related memories in female Marchigian Sardinian alcohol-preferring rats. Psychopharmacology (Berl). 2025 Nov 15. [Epub ahead of print]
Ebrahimi C, Musial MPM, Doñamayor N, Prychynenko DS, Bode EL, Spanagel R, Heinz A, Deserno L, Smolka MN, Ebner-Priemer U, Kliegl R, Endrass T, Reichert M, Rapp M, Schlagenhauf F. Goal-directed behavior and hippocampal activity predict real-life impact of drinking intentions in alcohol use disorder. Transl Psychiatry. 2025 15(1):425.
Freus NK, Wank I, Häfele M, Kalinichenko LS, Müller CP, Strobelt S, Ludwig A, Hess A, Kreitz S. Pharmacological and resting state fMRI reveal Osteocalcin's effects on mouse brain regions with high Gpr37 and Gpr158 expression. Sci Rep. 2025 15(1):10116.
Friske MM, Torrico EC, Haas MJW, Borruto AM, Giannone F, Hade AC, Yu Y, Gao L, Sutherland GT, Hitzemann R, Philips MA, Fei SS, Sommer WH, Mayfield RD, Spanagel R. A systematic review and meta-analysis on the transcriptomic signatures in alcohol use disorder. Mol Psychiatry. 2025 30(1):310-326. Epub 2024 Sep 6.
Habelt B, Talebi N, Afanasenkau D, Schwarz C, Knauer B, Meinhardt M, Spanagel R, Werner C, Minev IR, Beste C, Bernhardt N. Chronic alcohol-induced brain states limit propagation of direct cortical stimulation. Sci Rep. 2025 15(1):35407.
Hartnagel LM, Ebner-Priemer U, Foo JC, Streit F, Witt SH, Frank J, Limberger MF, Horn AB, Gilles M, Rietschel M, Sirignano L. Linguistic style as a digital marker for depression severity: An ambulatory assessment pilot study in patients with depressive disorder undergoing sleep deprivation therapy. Acta Psychiatr Scand. 2025 151(3):348-357. Epub 2024 Jul 10.
Heinz A, Gutwinski S, Friedel E, Bahr NS, Spanagel R, Chiara GD. Habitual Drug Intake Is Hard to Change: On the Discussion About Habits and Compulsions in Drug Addiction. Addict Biol. 2025 30(10):e70081.
Kalinichenko LS, Zoicas I, Bienia AM, Bühner C, Robinson J, Kütemeyer J, Labonte A, Raveendran T, Warth L, Smaga I, Filip M, Eulenburg V, Rhein C, Fejtova A, Gulbins E, Kornhuber J, Müller CP. Brain acid sphingomyelinase controls addiction-related behaviours in a sex-specific way. Neurobiol Dis. 2025 206:106800.
Liu S, Haucke M, Groß R, Schneider K, Shin J, Arntz F, Bach P, Banaschewski T, Beste C, Deserno L, Ebner-Priemer U, Endrass T, Ganz M, Ghadami A, Giurgiu M, Heinz A, Kiefer F, Kliegl R, Lenz B, Marciniak MA, Meyer-Lindenberg A, Neubauer AB, Rapp M, Smolka MN, Strehle J, Spanagel R, Spitta G, Tost H, Walter H, Zech H, Reichert D, Reichert M. Real-time mechanism-based interventions for daily alcohol challenges: Protocol for ecological momentary assessment and intervention. Digit Health. 2025 11:20552076241311731.
Meinhardt M, Skorodumov I, Jeanblanc J, Benvenuti F, Hilal FF, Domi E, André C, Bodeau S, Jeanblanc V, Domanegg K, Ciccocioppo R, Naassila M, Spanagel R. A new module in the drug development process: preclinical multi-center randomized controlled trial of R-ketamine on alcohol relapse. Neuropsychopharmacology. 2025 50(6):886-894. Epub 2025 Feb 28.
Müller CP, Khodamoradi M. The GABA receptor agonist baclofen inhibits the reconsolidation of methamphetamine reward memory in adolescent and adult REM sleep-deprived rats. Prog Neuropsychopharmacol Biol Psychiatry. 2025 141:111472.
Müller CP, Lenz B, Kornhuber J, Ebner-Priemer UW, Schwarz E, Ersche K, Kiefer F, Spanagel R. Phase-sensitive individualized pharmacotherapy for alcohol use disorder. Neuropharmacology. 2025 283:110745. Epub 2025 Oct 26.
Ramírez-Martín A, Sirignano L, Foo JC, Streit F, Frank J, Witt S, Rietschel M, Mayoral-Cleries F, Moreno-Küstner B, Guzman-Parra J. The relationships between impulsivity and mood in bipolar disorder: An ecological momentary assessment study. PLoS ONE. 2025 20(7):e0314963.
Schimmer J, Patwell R, Küppers S, Grinevich V. The Relationship Between Oxytocin and Alcohol Dependence. Curr Top Behav Neurosci. 2025 71:347-378. Epub 2023 Sep 12.
Schimmer S, Kania A, Lefevre A, Afordakos K, Wang K, Lebedeva J, Rozov A, Raftogianni A, Tiwari R, Netser S, Zovko A, Shaheen H, Schimmer J, Patwell R, Denis C, Grelot V, Petitjean H, Geng L, Hefter D, Boender A, Podpecan Y, Schommer F, Schubert I, Sanetra A, Trenk A, Gugula A, Hurlemann R, Wagner S, Li Y, Althammer F, Blasiak A, Melzer S, Monyer H, Charlet A, Eliava M, Grinevich V. Oxytocin facilitates social behavior of female rats via selective modulation of interneurons in the medial prefrontal cortex. bioRxiv. 2025
Sommer WH, Canals S. Alcohol-Induced Changes in Brain Microstructure: Uncovering Novel Pathophysiological Mechanisms of AUD Using Translational DTI in Humans and Rodents. Curr Top Behav Neurosci. 2025 72:595-617.
Sommer WH, Spanagel R. Behavioral Neurobiology of Alcohol Addiction: A Decade of Great Challenges, New Hopes, and Hypes. Curr Top Behav Neurosci. 2025 71:3-16. Epub 2025 Jul 12.
Stavrum AK, Zillich L, Frid LM, Frank J, Foo JC, Spindola LM, Höffler KD, Oedegaard KJ, Haavik J, Rietschel M, Witt S, Kessler U, Oltedal L, Le Hellard S. Epigenetic and blood markers associated with response to electroconvulsive therapy in patients with depressive disorders. Transl Psychiatry. 2025 16(1):32. Epub 2025 Dec 3.
Suhaimi FW, Khari NHM, Hassan Z, Müller CP. Exploring the cognitive effects of kratom: A review. Behav Brain Res. 2025 480:115387.
Trent S, Abdullah MH, Parwana K, Valdivieso MA, Hassan Z, Müller CP. Fear conditioning: Insights into learning, memory and extinction and its relevance to clinical disorders. Prog Neuropsychopharmacol Biol Psychiatry. 2025 138:111310. Epub 2025 Mar 6.
Vanes L, Rakesh D, Banaschewski T, Bodke ALW, Desrivieres S, Flor H, Garavan H, Gowland P, Grigis A, Heinz A, Lemaitre H, Martinot JL, Paillère Martinot ML, Artiges E, Nees F, Papadopoulos Orfanos D, Poustka L, Smolka MN, Hohmann S, Holz N, Vaidya N, Walter H, Whelan R, Schumann G, Barker GJ, IMAGEN Consortium . Longitudinal associations of structural and functional brain connectivity with dimensions of psychopathology in adolescence. Biol Psychiatry Cogn Neurosci Neuroimaging. 2025 Sep 24. [Epub ahead of print]
Varga L, Péntek B, Molnár B, Pérez-Cervera L, Selim MK, Díaz-Parra A, Moratal D, Sommer WH, Canals S, Mureșan RC, Moca VV, Ercsey-Ravasz M. Protocol to study brain dynamics of mammals through the hierarchy of complex correlation patterns defining a robust functional architecture. STAR Protoc. 2025 6(2):103693.
Vetter S, Schnabel S, Reichl M, Sirignano L, Grinevich V, Koopmann A, Spanagel R, Kiefer F, Sommer WH, Bach P. Intranasal oxytocin blunts amygdala response to negative affective stimuli in males and females with alcohol use disorder: a randomized controlled cross-over trial. Psychopharmacology (Berl). 2025 242(9):1995-2007. Epub 2025 Mar 31.
Wiegand A, Friske MM, Edelmann S, Bender A, Fischer L, Zill P, Koller G, Bakalkin G, Sommer WH, Hansson AC, Nieratschker V. Validation of and as Epigenetic Markers of Alcohol Use Disorder in Blood and Brain. Int J Mol Sci. 2025 26(22)
Zillich E, Artioli A, Rossetti AC, Avetyan D, Belschner H, Frank J, Stein F, Schwarz JJ, Mechawar N, Turecki G, Nöthen MM, Hansson AC, Witt CC, Rietschel M, Koch P, Spanagel R, Zillich L, Witt SH. A multi-omics and cell type-specific characterization of the ventral striatum in human cocaine use disorder. Cell Rep. 2025 44(2):115332. Epub 2025 Feb 14.
Zillich L, Artioli A, Pohorala V, Zillich E, Stertz L, Belschner H, Jabali A, Frank J, Streit F, Avetyan D, Völker MP, Müller S, Hansson AC, Meyer TD, Rietschel M, Ladewig J, Spanagel R, Oliveira A, Walss-Bass C, Bernardi R, Koch P, Witt SH. Cell type-specific multi-omics analysis of cocaine use disorder in the human caudate nucleus. Nat Commun. 2025 16(1):3381.
Zillich L, D'Augello S, Avetyan D, Delgado GE, Gizer IR, Jung J, Katrinli S, Kleber ME, Merrill N, Moissl AP, Núñez-Ríos DL, Otto JM, Zillich E, Friedel E, Hancock DB, Johnson EO, Martínez-Magaña JJ, Nagamatsu ST, Sosnowski DW, White JD, Aberg KA, Copeland WE, Diazgranados N, Fani N, Gelernter J, Goldman D, Foo JC, Kranzler HR, Levey DF, März W, Penninx BWJH, Polimanti R, Powers A, Smith AK, Spanagel R, van den Oord EJ, Wilhelmsen KC, Witt SH, Domschke K, Schiele MA, Maher BS, Montalvo Ortiz JL, Clark SL, Lohoff FW. DNA Methylation Signatures of Alcohol Use Disorder - A large-scale Meta-Analysis in the Psychiatric Genomics Consortium. medRxiv. 2025