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Huma Shaheen

PhD Student

Abteilung Neuropeptidforschung in der Psychiatrie

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About me

I hold a Master’s degree in Animal Sciences from PMAS-Arid Agriculture University, Rawalpindi, Pakistan. During my internship at the Institute of Biomedical and Genetic Engineering (IBGE), I worked on the genetics of rare neurological disorders in the Pakistani population, which inspired my interest in the neural mechanisms underlying complex behaviours.

 

Since December 2022, I have been pursuing my PhD in the Grinevich Lab, focusing on the role of central oxytocin signalling in modulating neural circuits that govern social and non-social reward processing. My research employs an integrative approach, combining operant self-administration paradigms, optogenetic circuit manipulation, and in vivo calcium imaging to investigate and modulate oxytocin-dependent neural dynamics.

 

Expertise

Operant conditioning  Stereotactic injections
Fiber photometryImmunohistochemistry     
Publikationen in peer-reviewed Zeitschriften seit 2006

TOP 5 Publikationen:

  1. Schimmer S, Kania A, Lefevre A, Afordakos K, Wang KY, Lebedeva J, Rozov A, Raftogianni A, Tiwari R, Netser S, Zovko A, Shaheen H, Schimmer J, Patwell R, Denis C, Grelot V, Petitjean H, Geng L, Hefter D, Boender A, Podpecan Y, Schommer F, Schubert T, Sanetra A, Trenk A, Gugula A, Hurlemann R, Wagner S, Li Y, Althammer F, Blasiak A, Melzer S, Monyer H, Charlet A, Eliava M, Grinevich V. Oxytocin facilitates social behavior of female rats via selective modulation of interneurons in the medial prefrontal cortex.Nat Commun. 2026 17(1).
  2. Schimmer S, Kania A, Lefevre A, Afordakos K, Wang K, Lebedeva J, Rozov A, Raftogianni A, Tiwari R, Netser S, Zovko A, Shaheen H, Schimmer J, Patwell R, Denis C, Grelot V, Petitjean H, Geng L, Hefter D, Boender A, Podpecan Y, Schommer F, Schubert I, Sanetra A, Trenk A, Gugula A, Hurlemann R, Wagner S, Li Y, Althammer F, Blasiak A, Melzer S, Monyer H, Charlet A, Eliava M, Grinevich V. Oxytocin facilitates social behavior of female rats via selective modulation of interneurons in the medial prefrontal cortexbioRxiv. 2025.

Zentralinstitut für Seelische Gesundheit (ZI) - https://www.zi-mannheim.de